Gene Review:
ABCC11 - ATP-binding cassette, sub-family C...
Homo sapiens
Synonyms:
ATP-binding cassette sub-family C member 11, EWWD, MRP8, Multidrug resistance-associated protein 8, WW
- MRP8/ABCC11 directly confers resistance to 5-fluorouracil. Oguri, T., Bessho, Y., Achiwa, H., Ozasa, H., Maeno, K., Maeda, H., Sato, S., Ueda, R. Mol. Cancer Ther. (2007)
- MRP8, a new member of ABC transporter superfamily, identified by EST database mining and gene prediction program, is highly expressed in breast cancer. Bera, T.K., Lee, S., Salvatore, G., Lee, B., Pastan, I. Mol. Med. (2001)
- MRP 8/14 and procalcitonin serum levels in organ transplantations. Stríz, I., Jaresová, M., Lácha, J., Sedlácek, J., Vítko, S. Ann. Transplant. (2001)
- The myeloic related protein MRP8/14 (27E10 antigen)--usefulness as a potential marker for disease activity in ulcerative colitis and putative biological function. Lügering, N., Stoll, R., Schmid, K.W., Kucharzik, T., Stein, H., Burmeister, G., Sorg, C., Domschke, W. Eur. J. Clin. Invest. (1995)
- Differential expression of the calcium-binding proteins MRP8 and MRP14 in granulomatous conditions: an immunohistochemical study. Delabie, J., de Wolf-Peeters, C., van den Oord, J.J., Desmet, V.J. Clin. Exp. Immunol. (1990)
- Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis. Passani, L.A., Bedford, M.T., Faber, P.W., McGinnis, K.M., Sharp, A.H., Gusella, J.F., Vonsattel, J.P., MacDonald, M.E. Hum. Mol. Genet. (2000)
- Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Nguyen, J.T., Turck, C.W., Cohen, F.E., Zuckermann, R.N., Lim, W.A. Science (1998)
- A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome. Murakami, M., Nakagawa, M., Olson, E.N., Nakagawa, O. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Myeloid-related proteins 8 and 14 induce a specific inflammatory response in human microvascular endothelial cells. Viemann, D., Strey, A., Janning, A., Jurk, K., Klimmek, K., Vogl, T., Hirono, K., Ichida, F., Foell, D., Kehrel, B., Gerke, V., Sorg, C., Roth, J. Blood (2005)
- MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes. Vogl, T., Ludwig, S., Goebeler, M., Strey, A., Thorey, I.S., Reichelt, R., Foell, D., Gerke, V., Manitz, M.P., Nacken, W., Werner, S., Sorg, C., Roth, J. Blood (2004)
- Impaired 2',3'-dideoxy-3'-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 with a possible role for ATP-binding cassette C11. Turriziani, O., Schuetz, J.D., Focher, F., Scagnolari, C., Sampath, J., Adachi, M., Bambacioni, F., Riva, E., Antonelli, G. Biochem. J. (2002)
- Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12. Tammur, J., Prades, C., Arnould, I., Rzhetsky, A., Hutchinson, A., Adachi, M., Schuetz, J.D., Swoboda, K.J., Ptácek, L.J., Rosier, M., Dean, M., Allikmets, R. Gene (2001)
- Characterization of the mouse Abcc12 gene and its transcript encoding an ATP-binding cassette transporter, an orthologue of human ABCC12. Shimizu, H., Taniguchi, H., Hippo, Y., Hayashizaki, Y., Aburatani, H., Ishikawa, T. Gene (2003)
- Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12. Yabuuchi, H., Shimizu, H., Takayanagi, S., Ishikawa, T. Biochem. Biophys. Res. Commun. (2001)
- Human multidrug resistance protein 8 (MRP8/ABCC11), an apical efflux pump for steroid sulfates, is an axonal protein of the CNS and peripheral nervous system. Bortfeld, M., Rius, M., König, J., Herold-Mende, C., Nies, A.T., Keppler, D. Neuroscience (2006)
- Increased serum levels of MRP-8/14 in type 1 diabetes induce an increased expression of CD11b and an enhanced adhesion of circulating monocytes to fibronectin. Bouma, G., Lam-Tse, W.K., Wierenga-Wolf, A.F., Drexhage, H.A., Versnel, M.A. Diabetes (2004)
- Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11). Chen, Z.S., Guo, Y., Belinsky, M.G., Kotova, E., Kruh, G.D. Mol. Pharmacol. (2005)
- MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine. Guo, Y., Kotova, E., Chen, Z.S., Lee, K., Hopper-Borge, E., Belinsky, M.G., Kruh, G.D. J. Biol. Chem. (2003)
- ABCC10, ABCC11, and ABCC12. Kruh, G.D., Guo, Y., Hopper-Borge, E., Belinsky, M.G., Chen, Z.S. Pflugers Arch. (2007)