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Gene Review

ECs0084  -  DNA-binding transcriptional regulator FruR

Escherichia coli O157:H7 str. Sakai

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Disease relevance of ECs0084


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Chemical compound and disease context of ECs0084


Biological context of ECs0084


Anatomical context of ECs0084


Associations of ECs0084 with chemical compounds


Analytical, diagnostic and therapeutic context of ECs0084


  1. Genomic analysis of LexA binding reveals the permissive nature of the Escherichia coli genome and identifies unconventional target sites. Wade, J.T., Reppas, N.B., Church, G.M., Struhl, K. Genes Dev. (2005) [Pubmed]
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  3. The Treponema pallidum tro operon encodes a multiple metal transporter, a zinc-dependent transcriptional repressor, and a semi-autonomously expressed phosphoglycerate mutase. Hazlett, K.R., Rusnak, F., Kehres, D.G., Bearden, S.W., La Vake, C.J., La Vake, M.E., Maguire, M.E., Perry, R.D., Radolf, J.D. J. Biol. Chem. (2003) [Pubmed]
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  6. Thermoregulation of Shigella and Escherichia coli EIEC pathogenicity. A temperature-dependent structural transition of DNA modulates accessibility of virF promoter to transcriptional repressor H-NS. Falconi, M., Colonna, B., Prosseda, G., Micheli, G., Gualerzi, C.O. EMBO J. (1998) [Pubmed]
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  8. BzdR, a repressor that controls the anaerobic catabolism of benzoate in Azoarcus sp. CIB, is the first member of a new subfamily of transcriptional regulators. Barragán, M.J., Blázquez, B., Zamarro, M.T., Mancheño, J.M., García, J.L., Díaz, E., Carmona, M. J. Biol. Chem. (2005) [Pubmed]
  9. Effect of the FruR regulator on transcription of the pts operon in Escherichia coli. Ryu, S., Ramseier, T.M., Michotey, V., Saier, M.H., Garges, S. J. Biol. Chem. (1995) [Pubmed]
  10. Application of AgaR repressor and dominant repressor variants for verification of a gene cluster involved in N-acetylgalactosamine metabolism in Escherichia coli K-12. Ray, W.K., Larson, T.J. Mol. Microbiol. (2004) [Pubmed]
  11. Osmoregulation in Lactococcus lactis: BusR, a transcriptional repressor of the glycine betaine uptake system BusA. Romeo, Y., Obis, D., Bouvier, J., Guillot, A., Fourçans, A., Bouvier, I., Gutierrez, C., Mistou, M.Y. Mol. Microbiol. (2003) [Pubmed]
  12. Regulation of expression of the ethanol dehydrogenase gene (adhE) in Escherichia coli by catabolite repressor activator protein Cra. Mikulskis, A., Aristarkhov, A., Lin, E.C. J. Bacteriol. (1997) [Pubmed]
  13. Catabolite regulation of two Escherichia coli operons encoding nitrite reductases: role of the Cra protein. Tyson, K., Busby, S., Cole, J. Arch. Microbiol. (1997) [Pubmed]
  14. Study of adaptive mutations in Salmonella typhimurium by using a super-repressing mutant of a trans regulatory gene purR. Yang, Z., Lu, Z., Wang, A. Mutat. Res. (2001) [Pubmed]
  15. Regulation of flavin dehydrogenase compartmentalization: requirements for PutA-membrane association in Salmonella typhimurium. Surber, M.W., Maloy, S. Biochim. Biophys. Acta (1999) [Pubmed]
  16. Plasmid pIP501 encoded transcriptional repressor CopR binds asymmetrically at two consecutive major grooves of the DNA. Steinmetzer, K., Brantl, S. J. Mol. Biol. (1997) [Pubmed]
  17. Fur-DNA interactions at the bidirectional fepDGC-entS promoter region in Escherichia coli. Lavrrar, J.L., Christoffersen, C.A., McIntosh, M.A. J. Mol. Biol. (2002) [Pubmed]
  18. Exploring the proline-dependent conformational change in the multifunctional PutA flavoprotein by tryptophan fluorescence spectroscopy. Zhu, W., Becker, D.F. Biochemistry (2005) [Pubmed]
  19. Genetic and biochemical characterization of a novel umuD mutation: insights into a mechanism for UmuD self-cleavage. Sutton, M.D., Kim, M., Walker, G.C. J. Bacteriol. (2001) [Pubmed]
  20. Host-specific incompatibility by 9-bp direct repeats indicates a role in the maintenance of broad-host-range plasmid RK2. Wilson, J.W., Figurski, D.H. Plasmid (2002) [Pubmed]
  21. The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1. Iype, T., Taylor, D.G., Ziesmann, S.M., Garmey, J.C., Watada, H., Mirmira, R.G. Mol. Endocrinol. (2004) [Pubmed]
  22. Membrane localization itself but not binding to IICB is directly responsible for the inactivation of the global repressor Mlc in Escherichia coli. Tanaka, Y., Itoh, F., Kimata, K., Aiba, H. Mol. Microbiol. (2004) [Pubmed]
  23. Redox properties of the PutA protein from Escherichia coli and the influence of the flavin redox state on PutA-DNA interactions. Becker, D.F., Thomas, E.A. Biochemistry (2001) [Pubmed]
  24. PerR controls oxidative stress resistance and iron storage proteins and is required for virulence in Staphylococcus aureus. Horsburgh, M.J., Clements, M.O., Crossley, H., Ingham, E., Foster, S.J. Infect. Immun. (2001) [Pubmed]
  25. Thermodynamic analysis of small ligand binding to the Escherichia coli repressor of biotin biosynthesis. Xu, Y., Johnson, C.R., Beckett, D. Biochemistry (1996) [Pubmed]
  26. Transcriptional control mediated by the ArcA two-component response regulator protein of Escherichia coli: characterization of DNA binding at target promoters. Lynch, A.S., Lin, E.C. J. Bacteriol. (1996) [Pubmed]
  27. Overexpression, purification, crystallization and preliminary X-ray diffraction analysis of the pMV158-encoded plasmid transcriptional repressor protein CopG. Gomis-Rüth, F.X., Solà, M., Pérez-Luque, R., Acebo, P., Alda, M.T., González, A., Espinosa, M., del Solar, G., Coll, M. FEBS Lett. (1998) [Pubmed]
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