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MeSH Review

Body Temperature Regulation

 
 
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Disease relevance of Body Temperature Regulation

 

Psychiatry related information on Body Temperature Regulation

 

High impact information on Body Temperature Regulation

  • Targeted disruption of the MC5-R produced mice with a severe defect in water repulsion and thermoregulation due to decreased production of sebaceous lipids [11].
  • Our findings strongly suggest that defects in TRKA cause CIPA and that the NGF-TRKA system has a crucial role in the development and function of the nociceptive reception as well as establishment of thermoregulation via sweating in humans [12].
  • We find that UCP-deficient mice consume less oxygen after treatment with a beta3-adrenergic-receptor agonist and that they are sensitive to cold, indicating that their thermoregulation is defective [13].
  • We have now identified and characterized a new regulatory locus (drdX) and show that a histone-like bacterial protein has an important role in this novel example of thermoregulation of transcription [14].
  • The fimbrial structures (pili) on the bacterial surface carry the adhesin and are present during growth at 37 degrees C but are not produced by cells at lower temperatures, such as 25 degrees C. Thermoregulation of expression is due to temperature-dependent transcription of a regulatory cistron in the pilus-adhesin gene cluster [14].
 

Chemical compound and disease context of Body Temperature Regulation

 

Biological context of Body Temperature Regulation

 

Anatomical context of Body Temperature Regulation

 

Associations of Body Temperature Regulation with chemical compounds

  • The fever may arise from the drug's pharmacologic action, its effects on thermoregulation, a local complication following parenteral administration, or an idiosyncratic response [29].
  • Expression of melatonin receptors in arteries involved in thermoregulation [30].
  • Studies in animals suggest that medullary raphé neurons are essential for cold-defense, mediating both the cutaneous vasoconstrictor and thermogenic responses to ambient cooling; however, the involvement of raphé neurons in human thermoregulation has not been investigated [31].
  • Previous data from our laboratory have indicated that 5-HT neuronal activity is unaffected by this manipulation, though 5-HT has been implicated specifically in thermoregulation [32].
  • These data indicate that ambient temperature has a significant affect on MDMA neurotoxicity, core temperature, and thermoregulation in rats [33].
 

Gene context of Body Temperature Regulation

  • As a result, Dgat(-/-) mice had impaired water repulsion and defective thermoregulation after water immersion [34].
  • These findings are consistent with the notion that UCP4 and UCP5 may be involved in tissue-specific thermoregulation and metabolic changes associated with nutritional status [35].
  • Starvation caused increased muscle and decreased BAT UCP3, suggesting that muscle assumes a larger role in thermoregulation during starvation [36].
  • We have obtained Elovl3-ablated mice and report here that, although cold-acclimated Elovl3-ablated mice experienced an increased heat loss due to impaired skin barrier, they were unable to hyperrecruit their brown adipose tissue [37].
  • These results suggest differential roles of BMCP1 and UCP2 in thermoregulation and aging [38].
 

Analytical, diagnostic and therapeutic context of Body Temperature Regulation

References

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