Gene Review:
HBVgp1 - Polymerase
Hepatitis B virus
- Mutations in the precore region of hepatitis B virus DNA in patients with fulminant and severe hepatitis. Omata, M., Ehata, T., Yokosuka, O., Hosoda, K., Ohto, M. N. Engl. J. Med. (1991)
- Occult hepatitis B virus infection in patients with chronic hepatitis C liver disease. Cacciola, I., Pollicino, T., Squadrito, G., Cerenzia, G., Orlando, M.E., Raimondo, G. N. Engl. J. Med. (1999)
- The reverse transcriptase of hepatitis B virus acts as a protein primer for viral DNA synthesis. Wang, G.H., Seeger, C. Cell (1992)
- Biosynthesis of the reverse transcriptase of hepatitis B viruses involves de novo translational initiation not ribosomal frameshifting. Chang, L.J., Pryciak, P., Ganem, D., Varmus, H.E. Nature (1989)
- The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance. Ono, S.K., Kato, N., Shiratori, Y., Kato, J., Goto, T., Schinazi, R.F., Carrilho, F.J., Omata, M. J. Clin. Invest. (2001)
- Polymerase chain reaction analysis of hepatitis B virus DNA in formalin-fixed, paraffin-embedded liver biopsies from alcoholics using a simplified and standardized amplification protocol. von Weizsäcker, F., Blum, H.E., Wands, J.R. J. Hepatol. (1994)
- The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis. Rehermann, B., Fowler, P., Sidney, J., Person, J., Redeker, A., Brown, M., Moss, B., Sette, A., Chisari, F.V. J. Exp. Med. (1995)
- In vivo expression of a new hepatitis B virus protein encoded by a spliced RNA. Soussan, P., Garreau, F., Zylberberg, H., Ferray, C., Brechot, C., Kremsdorf, D. J. Clin. Invest. (2000)
- Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase. Angus, P., Vaughan, R., Xiong, S., Yang, H., Delaney, W., Gibbs, C., Brosgart, C., Colledge, D., Edwards, R., Ayres, A., Bartholomeusz, A., Locarnini, S. Gastroenterology (2003)
- Effects of immunosuppressive therapy on viral markers in chronic active hepatitis B. Scullard, G.H., Smith, C.I., Merigan, T.C., Robinson, W.S., Gregory, P.B. Gastroenterology (1981)
- Inhibition of duck hepatitis B virus replication by 2',3'-dideoxycytidine. A potent inhibitor of reverse transcriptase. Kassianides, C., Hoofnagle, J.H., Miller, R.H., Doo, E., Ford, H., Broder, S., Mitsuya, H. Gastroenterology (1989)
- Selection of hepatitis B virus polymerase mutations in HIV-coinfected patients treated with tenofovir. Sheldon, J., Camino, N., Rodés, B., Bartholomeusz, A., Kuiper, M., Tacke, F., Núñez, M., Mauss, S., Lutz, T., Klausen, G., Locarnini, S., Soriano, V. Antivir. Ther. (Lond.) (2005)
- Transient selection of a hepatitis B virus polymerase gene mutant associated with a decreased replication capacity and famciclovir resistance. Pichoud, C., Seignères, B., Wang, Z., Trépo, C., Zoulim, F. Hepatology (1999)
- Mutation in HBV RNA-dependent DNA polymerase confers resistance to lamivudine in vivo. Tipples, G.A., Ma, M.M., Fischer, K.P., Bain, V.G., Kneteman, N.M., Tyrrell, D.L. Hepatology (1996)
- Uncommon mutation pattern of a hepatitis B virus isolate from genotype F infecting a patient with AIDS. Gomes, S.A., de Castro, L., Niel, C., Santos, E.A. J. Infect. (2004)
- Integrator enzyme hypothesis for replication of hepatitis-B virus. Hirschman, S.Z. Lancet (1975)
- Precore/core mutations of hepatitis B virus in hepatocellular carcinomas developed on noncirrhotic livers. Minami, M., Poussin, K., Kew, M., Okanoue, T., Bréchot, C., Paterlini, P. Gastroenterology (1996)
- Posttransfusion hepatitis revisited by hepatitis C antibody assays and polymerase chain reaction. Wang, J.T., Wang, T.H., Sheu, J.C., Lin, J.T., Wang, C.Y., Chen, D.S. Gastroenterology (1992)
- Hepatitis B virus core promoter sequence analysis in fulminant and chronic hepatitis B. Laskus, T., Rakela, J., Nowicki, M.J., Persing, D.H. Gastroenterology (1995)
- Resolution of chronic hepatitis B and anti-HBs seroconversion in humans by adoptive transfer of immunity to hepatitis B core antigen. Lau, G.K., Suri, D., Liang, R., Rigopoulou, E.I., Thomas, M.G., Mullerova, I., Nanji, A., Yuen, S.T., Williams, R., Naoumov, N.V. Gastroenterology (2002)
- Regulation of RNA polymerase I-dependent promoters by the hepatitis B virus X protein via activated Ras and TATA-binding protein. Wang, H.D., Trivedi, A., Johnson, D.L. Mol. Cell. Biol. (1998)
- Transcription of hepatitis B virus by RNA polymerase II. Rall, L.B., Standring, D.N., Laub, O., Rutter, W.J. Mol. Cell. Biol. (1983)
- The influence of a maternal chronic hepatitis B virus infection on the repertoire of transcribed T-cell receptor beta chain variable region genes in human cord blood. Abbott, W.G., Geursen, A., Fraser, J.D., Marbrook, J., Skinner, M.A., Tan, P.L. Hepatology (1995)
- Mimicry between the hepatitis B virus DNA polymerase and the antigenic targets of nuclear and smooth muscle antibodies in chronic hepatitis B virus infection. Gregorio, G.V., Choudhuri, K., Ma, Y., Vegnente, A., Mieli-Vergani, G., Vergani, D. J. Immunol. (1999)
- Hepatitis-B-virus resistance to lamivudine given for recurrent infection after orthotopic liver transplantation. Bartholomew, M.M., Jansen, R.W., Jeffers, L.J., Reddy, K.R., Johnson, L.C., Bunzendahl, H., Condreay, L.D., Tzakis, A.G., Schiff, E.R., Brown, N.A. Lancet (1997)
- Hepadnavirus assembly and reverse transcription require a multi-component chaperone complex which is incorporated into nucleocapsids. Hu, J., Toft, D.O., Seeger, C. EMBO J. (1997)
- Mutations in hepatitis B DNA polymerase associated with resistance to lamivudine do not confer resistance to adefovir in vitro. Xiong, X., Flores, C., Yang, H., Toole, J.J., Gibbs, C.S. Hepatology (1998)
- Selection of hepatitis B virus polymerase mutants with enhanced replication by lamivudine treatment after liver transplantation. Bock, C.T., Tillmann, H.L., Torresi, J., Klempnauer, J., Locarnini, S., Manns, M.P., Trautwein, C. Gastroenterology (2002)
- Redevelopment of hepatitis B surface antigen after renal transplantation. Marcellin, P., Giostra, E., Martinot-Peignoux, M., Loriot, M.A., Jaegle, M.L., Wolf, P., Degott, C., Degos, F., Benhamou, J.P. Gastroenterology (1991)
- Markedly prolonged incubation period of hepatitis B in a chimpanzee passively immunized with a human monoclonal antibody to the a determinant of hepatitis B surface antigen. Ogata, N., Ostberg, L., Ehrlich, P.H., Wong, D.C., Miller, R.H., Purcell, R.H. Proc. Natl. Acad. Sci. U.S.A. (1993)
- The natural course of chronic hepatitis C. Iwarson, S. FEMS Microbiol. Rev. (1994)