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MeSH Review

Hepatitis B Virus, Duck

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Disease relevance of Hepatitis B Virus, Duck


High impact information on Hepatitis B Virus, Duck


Chemical compound and disease context of Hepatitis B Virus, Duck

  • Duck hepatitis B virus deoxyribonucleic acid, which was measured in total cellular deoxyribonucleic acid extracted from liver biopsy specimens obtained before and on the last day of treatment with dideoxycytidine, showed an average inhibition of 96% in 3 ducks treated with dideoxycytidine, but showed no decrease in the remaining 5 ducks [6].
  • Furthermore, in vivo, penciclovir and its orally administered prodrug famciclovir strongly inhibited DHBV replication [9].
  • The antiviral effect of these inhibitors was also evaluated against 3TC-resistant mutants of the DHBV and HBV polymerases [10].
  • Long-term ganciclovir chemotherapy for congenital duck hepatitis B virus infection in vivo: effect on intrahepatic-viral DNA, RNA, and protein expression [11].
  • Moreover, both purine analogs remained active against DHBV and HBV 3TC-resistant mutants in transfected LMH and HepG2 cells, respectively [10].

Biological context of Hepatitis B Virus, Duck


Anatomical context of Hepatitis B Virus, Duck


Gene context of Hepatitis B Virus, Duck


Analytical, diagnostic and therapeutic context of Hepatitis B Virus, Duck


  1. Hepadnavirus assembly and reverse transcription require a multi-component chaperone complex which is incorporated into nucleocapsids. Hu, J., Toft, D.O., Seeger, C. EMBO J. (1997) [Pubmed]
  2. X gene-related sequences in the core gene of duck and heron hepatitis B viruses. Feitelson, M.A., Miller, R.H. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  3. Spectrum of liver disease and duck hepatitis B virus infection in a large series of Chinese ducks with hepatocellular carcinoma. Duflot, A., Mehrotra, R., Yu, S.Z., Barraud, L., Trepo, C., Cova, L. Hepatology (1995) [Pubmed]
  4. Central role of a serine phosphorylation site within duck hepatitis B virus core protein for capsid trafficking and genome release. Kock, J., Kann, M., Putz, G., Blum, H.E., Von Weizsacker, F. J. Biol. Chem. (2003) [Pubmed]
  5. Human DNA topoisomerase I-mediated cleavage and recombination of duck hepatitis B virus DNA in vitro. Pourquier, P., Jensen, A.D., Gong, S.S., Pommier, Y., Rogler, C.E. Nucleic Acids Res. (1999) [Pubmed]
  6. Inhibition of duck hepatitis B virus replication by 2',3'-dideoxycytidine. A potent inhibitor of reverse transcriptase. Kassianides, C., Hoofnagle, J.H., Miller, R.H., Doo, E., Ford, H., Broder, S., Mitsuya, H. Gastroenterology (1989) [Pubmed]
  7. Foscarnet decreases serum and liver duck hepatitis B virus DNA in chronically infected ducks. Sherker, A.H., Hirota, K., Omata, M., Okuda, K. Gastroenterology (1986) [Pubmed]
  8. Mechanism of translation of the hepadnaviral polymerase (P) gene. Chang, L.J., Ganem, D., Varmus, H.E. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  9. Antiviral activities of penciclovir and famciclovir on duck hepatitis B virus in vitro and in vivo. Offensperger, W.B., Offensperger, S., Keppler-Hafkemeyer, A., Hafkemeyer, P., Blum, H.E. Antivir. Ther. (Lond.) (1996) [Pubmed]
  10. Inhibitory activity of dioxolane purine analogs on wild-type and lamivudine-resistant mutants of hepadnaviruses. Seignères, B., Pichoud, C., Martin, P., Furman, P., Trépo, C., Zoulim, F. Hepatology (2002) [Pubmed]
  11. Long-term ganciclovir chemotherapy for congenital duck hepatitis B virus infection in vivo: effect on intrahepatic-viral DNA, RNA, and protein expression. Luscombe, C., Pedersen, J., Uren, E., Locarnini, S. Hepatology (1996) [Pubmed]
  12. Selective inhibition of the reverse transcription of duck hepatitis B virus by binding of 2',3'-dideoxyguanosine 5'-triphosphate to the viral polymerase. Howe, A.Y., Robins, M.J., Wilson, J.S., Tyrrell, D.L. Hepatology (1996) [Pubmed]
  13. Transmission of duck hepatitis B virus from Chinese carrier ducks to Japanese ducklings: a study of viral DNA in serum and tissue. Omata, M., Yokosuka, O., Imazeki, F., Matsuyama, Y., Uchiumi, K., Ito, Y., Mori, J., Okuda, K. Hepatology (1984) [Pubmed]
  14. The GDPAL region of the pre-S1 envelope protein is important for morphogenesis of woodchuck hepatitis virus. Yu, M., Emerson, S.U., Cote, P., Shapiro, M., Purcell, R.H. Hepatology (1998) [Pubmed]
  15. A sensitive procedure for mapping the boundaries of RNA elements binding in vitro translated proteins defines a minimal hepatitis B virus encapsidation signal. Beck, J., Nassal, M. Nucleic Acids Res. (1996) [Pubmed]
  16. In vitro transmission of duck hepatitis B virus to primary duck hepatocyte cultures. Uchida, T., Suzuki, K., Okuda, Y., Shikata, T. Hepatology (1988) [Pubmed]
  17. Replication of duck hepatitis B virus in primary duck hepatocytes and its dependence on the state of differentiation of the host cell. Galle, P.R., Schlicht, H.J., Kuhn, C., Schaller, H. Hepatology (1989) [Pubmed]
  18. Identification and expression of glycine decarboxylase (p120) as a duck hepatitis B virus pre-S envelope-binding protein. Li, J., Tong, S., Wands, J.R. J. Biol. Chem. (1999) [Pubmed]
  19. A cell surface protein that binds avian hepatitis B virus particles. Kuroki, K., Cheung, R., Marion, P.L., Ganem, D. J. Virol. (1994) [Pubmed]
  20. Characterization of the antiviral effect of 2',3'-dideoxy-2', 3'-didehydro-beta-L-5-fluorocytidine in the duck hepatitis B virus infection model. Le Guerhier, F., Pichoud, C., Guerret, S., Chevallier, M., Jamard, C., Hantz, O., Li, X.Y., Chen, S.H., King, I., Trépo, C., Cheng, Y.C., Zoulim, F. Antimicrob. Agents Chemother. (2000) [Pubmed]
  21. Recombinant duck interferon gamma inhibits duck hepatitis B virus replication in primary hepatocytes. Schultz, U., Chisari, F.V. J. Virol. (1999) [Pubmed]
  22. Role of p50/CDC37 in hepadnavirus assembly and replication. Wang, X., Grammatikakis, N., Hu, J. J. Biol. Chem. (2002) [Pubmed]
  23. Avian and Mammalian hepadnaviruses have distinct transcription factor requirements for viral replication. Tang, H., McLachlan, A. J. Virol. (2002) [Pubmed]
  24. Duck hepatitis B virus DNA in liver and serum of Chinese ducks: integration of viral DNA in a hepatocellular carcinoma. Yokosuka, O., Omata, M., Zhou, Y.Z., Imazeki, F., Okuda, K. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  25. Formation of a functional hepatitis B virus replication initiation complex involves a major structural alteration in the RNA template. Beck, J., Nassal, M. Mol. Cell. Biol. (1998) [Pubmed]
  26. Characterization of a pre-S polypeptide on the surfaces of infectious avian hepadnavirus particles. Pugh, J.C., Sninsky, J.J., Summers, J.W., Schaeffer, E. J. Virol. (1987) [Pubmed]
  27. Identification of an essential molecular contact point on the duck hepatitis B virus reverse transcriptase. Cao, F., Badtke, M.P., Metzger, L.M., Yao, E., Adeyemo, B., Gong, Y., Tavis, J.E. J. Virol. (2005) [Pubmed]
  28. Peptide mapping of neutralizing and nonneutralizing epitopes of duck hepatitis B virus pre-S polypeptide. Yuasa, S., Cheung, R.C., Pham, Q., Robinson, W.S., Marion, P.L. Virology (1991) [Pubmed]
  29. Minor envelope proteins of duck hepatitis B virus are initiated at internal pre-S AUG codons but are not essential for infectivity. Fernholz, D., Wildner, G., Will, H. Virology (1993) [Pubmed]
  30. Duck hepatitis B virus infection, aflatoxin B1 and liver cancer in domestic Chinese ducks. Cova, L., Mehrotra, R., Wild, C.P., Chutimataewin, S., Cao, S.F., Duflot, A., Prave, M., Yu, S.Z., Montesano, R., Trepo, C. Br. J. Cancer (1994) [Pubmed]
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