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Gene Review

dinD  -  DNA damage-inducible protein

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK3635, JW3620, orfY, pcsA, yicD
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Disease relevance of dinD


High impact information on dinD


Biological context of dinD


Associations of dinD with chemical compounds


Other interactions of dinD


Analytical, diagnostic and therapeutic context of dinD

  • Insertion of the element was site specific, as PCR and Southern blotting analysis revealed that the erm(B) element was inserted into orfY, a gene of unknown function [21].


  1. Bile salt activation of stress response promoters in Escherichia coli. Bernstein, C., Bernstein, H., Payne, C.M., Beard, S.E., Schneider, J. Curr. Microbiol. (1999) [Pubmed]
  2. Lex marks the spot: the virulent side of SOS and a closer look at the LexA regulon. Kelley, W.L. Mol. Microbiol. (2006) [Pubmed]
  3. LexA-independent DNA damage-mediated induction of gene expression in Myxococcus xanthus. Campoy, S., Fontes, M., Padmanabhan, S., Cortés, P., Llagostera, M., Barbé, J. Mol. Microbiol. (2003) [Pubmed]
  4. Cloning and characterization of DNA damage-inducible promoter regions from Bacillus subtilis. Cheo, D.L., Bayles, K.W., Yasbin, R.E. J. Bacteriol. (1991) [Pubmed]
  5. Identification of some DNA damage-inducible genes of Mycobacterium tuberculosis: apparent lack of correlation with LexA binding. Brooks, P.C., Movahedzadeh, F., Davis, E.O. J. Bacteriol. (2001) [Pubmed]
  6. Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma. Crozat, A., Aman, P., Mandahl, N., Ron, D. Nature (1993) [Pubmed]
  7. Homologous recombination-dependent initiation of DNA replication from DNA damage-inducible origins in Escherichia coli. Asai, T., Sommer, S., Bailone, A., Kogoma, T. EMBO J. (1993) [Pubmed]
  8. DNA polymerase II is encoded by the DNA damage-inducible dinA gene of Escherichia coli. Bonner, C.A., Hays, S., McEntee, K., Goodman, M.F. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  9. Why OrfY? Characterization of MMOD, a long overlooked component of the soluble methane monooxygenase from Methylococcus capsulatus (Bath). Merkx, M., Lippard, S.J. J. Biol. Chem. (2002) [Pubmed]
  10. Escherichia coli cells defective for the recN gene display constitutive elevation of mutagenesis at 3,N(4)-ethenocytosine via an SOS-induced mechanism. Dunman, P.M., Ren, L., Rahman, M.S., Palejwala, V.A., Murphy, H.S., Volkert, M.R., Humayun, M.Z. Mol. Microbiol. (2000) [Pubmed]
  11. Identification of high affinity binding sites for LexA which define new DNA damage-inducible genes in Escherichia coli. Lewis, L.K., Harlow, G.R., Gregg-Jolly, L.A., Mount, D.W. J. Mol. Biol. (1994) [Pubmed]
  12. Molecular and mutational analysis of three genes preceding pyrE on the Escherichia coli chromosome. Poulsen, P., Andersen, J.T., Jensen, K.F. Mol. Microbiol. (1989) [Pubmed]
  13. Three genes preceding pyrE on the Escherichia coli chromosome are essential for survival and normal cell morphology in stationary culture and at high temperature. Poulsen, P., Jensen, K.F. Res. Microbiol. (1991) [Pubmed]
  14. Inducible UV repair potential of Pseudomonas aeruginosa PAO. Simonson, C.S., Kokjohn, T.A., Miller, R.V. J. Gen. Microbiol. (1990) [Pubmed]
  15. The damage-inducible (din) genes of Escherichia coli are induced by various genotoxins in a different way. Oh, T.J., Lee, C.W., Kim, I.G. Microbiol. Res. (1999) [Pubmed]
  16. Cloning and genetic analysis of the UV resistance determinant (uvr) encoded on the Enterococcus faecalis pheromone-responsive conjugative plasmid pAD1. Ozawa, Y., Tanimoto, K., Fujimoto, S., Tomita, H., Ike, Y. J. Bacteriol. (1997) [Pubmed]
  17. An inducible pathway is required for mutagenesis in Salmonella typhimurium LT2. Orrego, C., Eisenstadt, E. J. Bacteriol. (1987) [Pubmed]
  18. The uvrB gene of Pseudomonas aeruginosa is not DNA damage inducible. Rivera, E., Vila, L., Barbé, J. J. Bacteriol. (1996) [Pubmed]
  19. A putative SOS repair gene (dinF-like) in a hyperthermophilic archaeon. Bouyoub, A., Barbier, G., Querellou, J., Forterre, P. Gene (1995) [Pubmed]
  20. Expression of the Pseudomonas aeruginosa uvrA gene is constitutive. Rivera, E., Vila, L., Barbé, J. Mutat. Res. (1997) [Pubmed]
  21. A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes. Jost, B.H., Trinh, H.T., Songer, J.G., Billington, S.J. Antimicrob. Agents Chemother. (2004) [Pubmed]
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