Gene Review:
Z1051m - L-asparaginase
Escherichia coli O157:H7 str. EDL933
Avramis,
Panosyan,
Hawkins,
Park,
Thomson,
Felgenhauer,
Holcenberg,
Panosyan,
Avramis,
Moghrabi,
Levy,
Asselin,
Barr,
Clavell,
Hurwitz,
Samson,
Schorin,
Dalton,
Lipshultz,
Neuberg,
Gelber,
Cohen,
Sallan,
Silverman,
Avramis,
Sencer,
Periclou,
Sather,
Bostrom,
Cohen,
Ettinger,
Ettinger,
Franklin,
Gaynon,
Hilden,
Lange,
Majlessipour,
Mathew,
Needle,
Neglia,
Reaman,
Holcenberg,
Stork,
Duval,
Suciu,
Ferster,
Rialland,
Nelken,
Lutz,
Benoit,
Robert,
Manel,
Vilmer,
Otten,
Philippe,
- Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy. Swain, A.L., Jaskólski, M., Housset, D., Rao, J.K., Wlodawer, A. Proc. Natl. Acad. Sci. U.S.A. (1993)
- A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children's Cancer Group study. Avramis, V.I., Sencer, S., Periclou, A.P., Sather, H., Bostrom, B.C., Cohen, L.J., Ettinger, A.G., Ettinger, L.J., Franklin, J., Gaynon, P.S., Hilden, J.M., Lange, B., Majlessipour, F., Mathew, P., Needle, M., Neglia, J., Reaman, G., Holcenberg, J.S., Stork, L. Blood (2002)
- Results of the Dana-Farber Cancer Institute ALL Consortium Protocol 95-01 for children with acute lymphoblastic leukemia. Moghrabi, A., Levy, D.E., Asselin, B., Barr, R., Clavell, L., Hurwitz, C., Samson, Y., Schorin, M., Dalton, V.K., Lipshultz, S.E., Neuberg, D.S., Gelber, R.D., Cohen, H.J., Sallan, S.E., Silverman, L.B. Blood (2007)
- Comparison of Escherichia coli-asparaginase with Erwinia-asparaginase in the treatment of childhood lymphoid malignancies: results of a randomized European Organisation for Research and Treatment of Cancer-Children's Leukemia Group phase 3 trial. Duval, M., Suciu, S., Ferster, A., Rialland, X., Nelken, B., Lutz, P., Benoit, Y., Robert, A., Manel, A.M., Vilmer, E., Otten, J., Philippe, N. Blood (2002)
- Hypersensitivity or development of antibodies to asparaginase does not impact treatment outcome of childhood acute lymphoblastic leukemia. Woo, M.H., Hak, L.J., Storm, M.C., Sandlund, J.T., Ribeiro, R.C., Rivera, G.K., Rubnitz, J.E., Harrison, P.L., Wang, B., Evans, W.E., Pui, C.H., Relling, M.V. J. Clin. Oncol. (2000)
- Prevention of methotrexate cytotoxicity by asparaginase inhibition of methotrexate polyglutamate formation. Jolivet, J., Cole, D.E., Holcenberg, J.S., Poplack, D.G. Cancer Res. (1985)
- Role of Glutamine Depletion in Directing Tissue-specific Nutrient Stress Responses to L-Asparaginase. Reinert, R.B., Oberle, L.M., Wek, S.A., Bunpo, P., Wang, X.P., Mileva, I., Goodwin, L.O., Aldrich, C.J., Durden, D.L., McNurlan, M.A., Wek, R.C., Anthony, T.G. J. Biol. Chem. (2006)
- Weekly polyethylene glycol conjugated L-asparaginase compared with biweekly dosing produces superior induction remission rates in childhood relapsed acute lymphoblastic leukemia: a Pediatric Oncology Group Study. Abshire, T.C., Pollock, B.H., Billett, A.L., Bradley, P., Buchanan, G.R. Blood (2000)
- L-asparaginase pharmacokinetics and asparagine levels in cerebrospinal fluid of rhesus monkeys and humans. Riccardi, R., Holcenberg, J.S., Glaubiger, D.L., Wood, J.H., Poplack, D.G. Cancer Res. (1981)
- Crystal structure of isoaspartyl aminopeptidase in complex with L-aspartate. Michalska, K., Brzezinski, K., Jaskolski, M. J. Biol. Chem. (2005)
- Enzyme-induced asparagine and glutamine depletion and immune system function. Kafkewitz, D., Bendich, A. Am. J. Clin. Nutr. (1983)
- Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia. Hawkins, D.S., Park, J.R., Thomson, B.G., Felgenhauer, J.L., Holcenberg, J.S., Panosyan, E.H., Avramis, V.I. Clin. Cancer Res. (2004)
- Pharmacokinetic/pharmacodynamic relationships of asparaginase formulations: the past, the present and recommendations for the future. Avramis, V.I., Panosyan, E.H. Clinical pharmacokinetics. (2005)
- Cerebrospinal fluid asparagine concentrations after Escherichia coli asparaginase in children with acute lymphoblastic leukemia. Woo, M.H., Hak, L.J., Storm, M.C., Gajjar, A.J., Sandlund, J.T., Harrison, P.L., Wang, B., Pui, C.H., Relling, M.V. J. Clin. Oncol. (1999)
- Mapping of B-cell epitopes in E. coli asparaginase II, an enzyme used in leukemia treatment. Werner, A., Röhm, K.H., Müller, H.J. Biol. Chem. (2005)
- Asparaginase display of polypeptides in the periplasm of Escherichia coli: potential rapid pepscan technique for antigen epitope mapping. Gaofu, Q., Jie, L., Rongyue, C., Xin, Y., Dan, M., Jie, W., Xiangchun, S., Qunwei, X., Roque, R.S., Xiuyun, Z., Jingjing, L. J. Immunol. Methods (2005)
- Glycosylation of Escherichia coli L-asparaginase. Marsh, J.W., Denis, J., Wriston, J.C. J. Biol. Chem. (1977)
- L-asparaginase genes in Escherichia coli: isolation of mutants and characterization of the ansA gene and its protein product. Spring, K.J., Jerlström, P.G., Burns, D.M., Beacham, I.R. J. Bacteriol. (1986)
- Modification of cystine or tryptophan residues in the asparaginase molecule and their role in conformation and antigenicity. Saito, T., Obata, M., Todokora, K., Okubo, M., Minowa, M. FEBS Lett. (1976)
- Effect of culture conditions on synthesis of L-asparaginase by Escherichia coli A-1. Barnes, W.R., Dorn, G.L., Vela, G.R. Appl. Environ. Microbiol. (1977)
- Site-specific mutagenesis of Escherichia coli asparaginase II. None of the three histidine residues is required for catalysis. Wehner, A., Harms, E., Jennings, M.P., Beacham, I.R., Derst, C., Bast, P., Röhm, K.H. Eur. J. Biochem. (1992)
- Comparative pharmacokinetic studies of three asparaginase preparations. Asselin, B.L., Whitin, J.C., Coppola, D.J., Rupp, I.P., Sallan, S.E., Cohen, H.J. J. Clin. Oncol. (1993)
- Biosensor for asparagine using a thermostable recombinant asparaginase from Archaeoglobus fulgidus. Li, J., Wang, J., Bachas, L.G. Anal. Chem. (2002)
- Anti-asparaginase antibodies following E. coli asparaginase therapy in pediatric acute lymphoblastic leukemia. Woo, M.H., Hak, L.J., Storm, M.C., Evans, W.E., Sandlund, J.T., Rivera, G.K., Wang, B., Pui, C.H., Relling, M.V. Leukemia (1998)
- A catalytic role for threonine-12 of E. coli asparaginase II as established by site-directed mutagenesis. Harms, E., Wehner, A., Aung, H.P., Röhm, K.H. FEBS Lett. (1991)