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MeSH Review

Injections, Spinal

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  1. Increased motoneuron survival and improved neuromuscular function in transgenic ALS mice after intraspinal injection of an adeno-associated virus encoding Bcl-2. Azzouz, M., Hottinger, A., Paterna, J.C., Zurn, A.D., Aebischer, P., Büeler, H. Hum. Mol. Genet. (2000) [Pubmed]
  2. Effects of 4-aminopyridine on demyelinated axons, synapses and muscle tension. Smith, K.J., Felts, P.A., John, G.R. Brain (2000) [Pubmed]
  3. Exogenous and endogenous adenosine enhance the spinal antiallodynic effects of morphine in a rat model of neuropathic pain. Lavand'homme, P.M., Eisenach, J.C. Pain (1999) [Pubmed]
  4. Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat. Joseph, E.K., Chen, X., Khasar, S.G., Levine, J.D. Pain (2004) [Pubmed]
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  6. Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia. Yaksh, T.L., Farb, D.H., Leeman, S.E., Jessell, T.M. Science (1979) [Pubmed]
  7. Antinociceptive effect of intrathecally administered serotonin. Wang, J.K. Anesthesiology (1977) [Pubmed]
  8. Intrathecal baclofen for the treatment of dystonia in patients with reflex sympathetic dystrophy. van Hilten, B.J., van de Beek, W.J., Hoff, J.I., Voormolen, J.H., Delhaas, E.M. N. Engl. J. Med. (2000) [Pubmed]
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  12. BDNF is necessary and sufficient for spinal respiratory plasticity following intermittent hypoxia. Baker-Herman, T.L., Fuller, D.D., Bavis, R.W., Zabka, A.G., Golder, F.J., Doperalski, N.J., Johnson, R.A., Watters, J.J., Mitchell, G.S. Nat. Neurosci. (2004) [Pubmed]
  13. Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination. Woodruff, R.H., Fruttiger, M., Richardson, W.D., Franklin, R.J. Mol. Cell. Neurosci. (2004) [Pubmed]
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  15. Effects of intrathecally administered nociceptin, an opioid receptor-like1 receptor agonist, and N-methyl-D-aspartate receptor antagonists on the thermal hyperalgesia induced by partial sciatic nerve injury in the rat. Yamamoto, T., Nozaki-Taguchi, N. Anesthesiology (1997) [Pubmed]
  16. Intrathecal or dietary glycine inhibits bladder and urethral activity in rats with spinal cord injury. Miyazato, M., Sugaya, K., Nishijima, S., Kadekawa, K., Ashimine, S., Ogawa, Y. J. Urol. (2005) [Pubmed]
  17. Involvement of spinal cord nuclear factor kappaB activation in rat models of proinflammatory cytokine-mediated pain facilitation. Ledeboer, A., Gamanos, M., Lai, W., Martin, D., Maier, S.F., Watkins, L.R., Quan, N. Eur. J. Neurosci. (2005) [Pubmed]
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  19. Repeated intrathecal administration of plasmid DNA complexed with polyethylene glycol-grafted polyethylenimine led to prolonged transgene expression in the spinal cord. Shi, L., Tang, G.P., Gao, S.J., Ma, Y.X., Liu, B.H., Li, Y., Zeng, J.M., Ng, Y.K., Leong, K.W., Wang, S. Gene Ther. (2003) [Pubmed]
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  21. 5-aminocoumarans: dual inhibitors of lipid peroxidation and dopamine release with protective effects against central nervous system trauma and ischemia. Ohkawa, S., Fukatsu, K., Miki, S., Hashimoto, T., Sakamoto, J., Doi, T., Nagai, Y., Aono, T. J. Med. Chem. (1997) [Pubmed]
  22. Pharmacological characterization of spinal alpha adrenoceptors related to blood pressure control in rats. Kubo, T., Nagura, J., Misu, Y. J. Pharmacol. Exp. Ther. (1987) [Pubmed]
  23. The spinal biology in humans and animals of pain states generated by persistent small afferent input. Yaksh, T.L., Hua, X.Y., Kalcheva, I., Nozaki-Taguchi, N., Marsala, M. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  24. Restoration of normal conduction properties in demyelinated spinal cord axons in the adult rat by transplantation of exogenous Schwann cells. Honmou, O., Felts, P.A., Waxman, S.G., Kocsis, J.D. J. Neurosci. (1996) [Pubmed]
  25. Prolongation of drug exposure in cerebrospinal fluid by encapsulation into DepoFoam. Kim, S., Khatibi, S., Howell, S.B., McCully, C., Balis, F.M., Poplack, D.G. Cancer Res. (1993) [Pubmed]
  26. Physiological effects of 4-aminopyridine on demyelinated mammalian motor and sensory fibers. Bowe, C.M., Kocsis, J.D., Targ, E.F., Waxman, S.G. Ann. Neurol. (1987) [Pubmed]
  27. Identification of post-mitotic oligodendrocytes incapable of remyelination within the demyelinated adult spinal cord. Keirstead, H.S., Blakemore, W.F. J. Neuropathol. Exp. Neurol. (1997) [Pubmed]
  28. Noxious thermal and chemical stimulation induce increases in 3H-phorbol 12,13-dibutyrate binding in spinal cord dorsal horn as well as persistent pain and hyperalgesia, which is reduced by inhibition of protein kinase C. Yashpal, K., Pitcher, G.M., Parent, A., Quirion, R., Coderre, T.J. J. Neurosci. (1995) [Pubmed]
  29. Behavioral sensitization to kainic acid and quisqualic acid in mice: comparison to NMDA and substance P responses. Sun, X.F., Larson, A.A. J. Neurosci. (1991) [Pubmed]
  30. High-dose methotrexate-based chemotherapy followed by consolidating radiotherapy in non-AIDS-related primary central nervous system lymphoma: European Organization for Research and Treatment of Cancer Lymphoma Group Phase II Trial 20962. Poortmans, P.M., Kluin-Nelemans, H.C., Haaxma-Reiche, H., Van't Veer, M., Hansen, M., Soubeyran, P., Taphoorn, M., Thomas, J., Van den Bent, M., Fickers, M., Van Imhoff, G., Rozewicz, C., Teodorovic, I., van Glabbeke, M. J. Clin. Oncol. (2003) [Pubmed]
  31. Prostaglandins inhibit endogenous pain control mechanisms by blocking transmission at spinal noradrenergic synapses. Taiwo, Y.O., Levine, J.D. J. Neurosci. (1988) [Pubmed]
  32. Intrathecal gene therapy for malignant leptomeningeal neoplasia. Ram, Z., Walbridge, S., Oshiro, E.M., Viola, J.J., Chiang, Y., Mueller, S.N., Blaese, R.M., Oldfield, E.H. Cancer Res. (1994) [Pubmed]
  33. Suppressed injury-induced rise in spinal prostaglandin E2 production and reduced early thermal hyperalgesia in iNOS-deficient mice. Gühring, H., Görig, M., Ates, M., Coste, O., Zeilhofer, H.U., Pahl, A., Rehse, K., Brune, K. J. Neurosci. (2000) [Pubmed]
  34. ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model. Zhuang, Z.Y., Gerner, P., Woolf, C.J., Ji, R.R. Pain (2005) [Pubmed]
  35. Analysis of the role of endothelin-A and endothelin-B receptors on nociceptive information transmission in the spinal cord with FR139317, an endothelin-A receptor antagonist, and sarafotoxin S6c, an endothelin-B receptor agonist. Yamamoto, T., Shimoyama, N., Asano, H., Mizuguchi, T. J. Pharmacol. Exp. Ther. (1994) [Pubmed]
  36. Nociceptive behavior after intrathecal injections of substance P, neurokinin A and calcitonin gene-related peptide in mice. Gamse, R., Saria, A. Neurosci. Lett. (1986) [Pubmed]
  37. Analgesic effect of vitamin E is mediated by reducing central sensitization in neuropathic pain. Kim, H.K., Kim, J.H., Gao, X., Zhou, J.L., Lee, I., Chung, K., Chung, J.M. Pain (2006) [Pubmed]
  38. Synergy between the antinociceptive effects of intrathecal clonidine and systemic morphine in the rat. Drasner, K., Fields, H.L. Pain (1988) [Pubmed]
  39. Action of peptidase inhibitors on methionine5-enkephalin-arginine6-phenylalanine7 (YGGFMRF) and methionine5-enkephalin (YGGFM) metabolism and on electroacupuncture antinociception. Chou, J., Tang, J., Del Rio, J., Yang, H.Y., Costa, E. J. Pharmacol. Exp. Ther. (1984) [Pubmed]
  40. Spinal carbonic anhydrase contributes to nociceptive reflex enhancement by midazolam, pentobarbital, and propofol. Wang, B., Samanani, N., Roth, S.H., Archer, D.P. Anesthesiology (2003) [Pubmed]
  41. Ultrastructural evidence that substance P neurons form synapses with noradrenergic neurons in the A7 catecholamine cell group that modulate nociception. Proudfit, H.K., Monsen, M. Neuroscience (1999) [Pubmed]
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