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MeSH Review


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Disease relevance of Sarcocystis


High impact information on Sarcocystis

  • Two monoclonal antibodies directed against a microneme antigen of Sarcocystis muris cyst merozoites (16/17 kDa band doublet) were used to isolate cDNA clones from a lambda ZAP expression library [6].
  • Partial sequences of the small subunit ribosomal RNA of four species of Sarcocystis were obtained by reverse transcription of total cellular RNA [7].
  • Based on electrophoresis, there appeared to be modification of at least some Sarcocystis polypeptides in the mol. wt range 17,000-30,000 [8].
  • Association with Sarcocystis suggests a new role for bFGF in the context of parasitic invasion and establishment [9].
  • A hydrophobic, galactose-specific lectin was isolated by means of affinity chromatography from Sarcocystis gigantea [10].

Chemical compound and disease context of Sarcocystis


Anatomical context of Sarcocystis


Associations of Sarcocystis with chemical compounds


Gene context of Sarcocystis

  • Detection of Sarcocystis antigens in the sera of experimentally-infected pigs and mice by an immunoenzymatic assay [21].
  • Similar studies were done in laboratory rabbits inoculated with N caninum, T gondii, Hammondia hammondi, and Sarcocystis sp. Additionally, sera were obtained from ewes, lambs, goats, sows, cats, rats, and mice inoculated with N caninum tachyzoites [22].
  • Interferon-gamma knockout (IFN-gamma KO) mice were infected with Sarcocystis neurona merozoites to characterize the immunopathology associated with infection [23].
  • Plasma and tissue concentrations and molecular forms of somatostatin in calves infected with Sarcocystis cruzi [24].
  • Sarcocystis zoites were found in pepsin digests of 68.8% of 157 pigs from Hissar, Haryana [25].

Analytical, diagnostic and therapeutic context of Sarcocystis


  1. Amprolium for prophylaxis of ovine Sarcocystis. Leek, R.G., Fayer, R. J. Parasitol. (1980) [Pubmed]
  2. The effects of Sarcocystis miescheriana infections on blood enzymes and weight gain of stress-sensitive and stress-insensitive pigs. Daugschies, A., Schnieder, T., Rommel, M., Bickhardt, K. Vet. Parasitol. (1988) [Pubmed]
  3. Multifocal myositis associated with Sarcocystis sp in a horse. Traub-Dargatz, J.L., Schlipf, J.W., Granstrom, D.E., Ingram, J.T., Shelton, G.D., Getzy, D.M., Lappin, M.R., Baker, D.C. J. Am. Vet. Med. Assoc. (1994) [Pubmed]
  4. Encephalomyelitis associated with a Sarcocystis neurona-like organism in a sea otter. Rosonke, B.J., Brown, S.R., Tornquist, S.J., Snyder, S.P., Garner, M.M., Blythe, L.L. J. Am. Vet. Med. Assoc. (1999) [Pubmed]
  5. Investigation of Sarcocystis as a causative agent in cardiac disease. Azab, M.E., el-Shennawy, S.F. Journal of the Egyptian Society of Parasitology. (1992) [Pubmed]
  6. Characterization of cDNA clones encoding a major microneme antigen of Sarcocystis muris (Apicomplexa) cyst merozoites. Eschenbacher, K.H., Klein, H., Sommer, I., Meyer, H.E., Entzeroth, R., Mehlhorn, H., Rüger, W. Mol. Biochem. Parasitol. (1993) [Pubmed]
  7. Phylogenetic relationships of Sarcocystis species from sheep, goats, cattle and mice based on ribosomal RNA sequences. Tenter, A.M., Baverstock, P.R., Johnson, A.M. Int. J. Parasitol. (1992) [Pubmed]
  8. Comparison of in vitro translation products of Sarcocystis gigantea and Sarcocystis tenella. Tenter, A.M., Johnson, A.M. Int. J. Parasitol. (1992) [Pubmed]
  9. A potential new role for bFGF in host-parasite interactions. Kardami, E. Growth Factors (1990) [Pubmed]
  10. Isolation and characterization of a lectin from Sarcocystis gigantea. Mácha, J., Procházková, Z., Cerva, L., Gut, J. Mol. Biochem. Parasitol. (1985) [Pubmed]
  11. Evaluation of decoquinate, lasalocid, and monensin against experimentally induced sarcocystosis in calves. Foreyt, W.J. Am. J. Vet. Res. (1986) [Pubmed]
  12. The outdoor survival of Sarcocystis gigantea sporocysts. McKenna, P.B., Charleston, W.A. Vet. Parasitol. (1994) [Pubmed]
  13. In vitro excystation of Sarcocystis capracanis, Sarcocystis cruzi and Sarcocystis tenella (Apicomplexa). Cawthorn, R.J., Reduker, D.W., Speer, C.A., Dubey, J.P. J. Parasitol. (1986) [Pubmed]
  14. Neospora-like protozoal infections associated with bovine abortions. Barr, B.C., Anderson, M.L., Dubey, J.P., Conrad, P.A. Vet. Pathol. (1991) [Pubmed]
  15. Prostanoids during acute sarcocystiosis in growing pigs. Daugschies, A., Rommel, M., Hoppen, H.O. Parasitol. Res. (1989) [Pubmed]
  16. Lysates of Sarcocystis cruzi bradyzoites stimulate RAW 264.7 macrophages to produce tumor necrosis factor (cachectin). Fayer, R., Andrews, C., Dubey, J.P. J. Parasitol. (1988) [Pubmed]
  17. Effects of Sarcocystis miescheriana infection on carcass weight and meat quality of halothane-tested fattening pigs. Daugschies, A., Rommel, M., Schnieder, T., Henning, M., Kallweit, E. Vet. Parasitol. (1987) [Pubmed]
  18. Effect of daily administration of pyrantel tartrate in preventing infection in horses experimentally challenged with Sarcocystis neurona. Rossano, M.G., Schott, H.C., Kaneene, J.B., Murphy, A.J., Kruttlin, E.A., Hines, M.T., Sellon, D.C., Patterson, J.S., Elsheikha, H.M., Dubey, J.P., Mansfield, L.S. Am. J. Vet. Res. (2005) [Pubmed]
  19. Determination of the activity of diclazuril against Sarcocystis neurona and Sarcocystis falcatula in cell cultures. Lindsay, D.S., Dubey, J.P. J. Parasitol. (2000) [Pubmed]
  20. Determination of the activity of ponazuril against Sarcocystis neurona in cell cultures. Lindsay, D.S., Dubey, J.P., Kennedy, T.J. Vet. Parasitol. (2000) [Pubmed]
  21. Detection of Sarcocystis antigens in the sera of experimentally-infected pigs and mice by an immunoenzymatic assay. O'Donoghue, P.J., Weyreter, H. Vet. Parasitol. (1983) [Pubmed]
  22. Serologic responses of cattle and other animals infected with Neospora caninum. Dubey, J.P., Lindsay, D.S., Adams, D.S., Gay, J.M., Baszler, T.V., Blagburn, B.L., Thulliez, P. Am. J. Vet. Res. (1996) [Pubmed]
  23. Immunopathologic effects associated with Sarcocystis neurona-infected interferon-gamma knockout mice. Witonsky, S.G., Gogal, R.M., Duncan, R.B., Lindsay, D.S. J. Parasitol. (2003) [Pubmed]
  24. Plasma and tissue concentrations and molecular forms of somatostatin in calves infected with Sarcocystis cruzi. Elsasser, T.H., Fayer, R., Rumsey, T.S., Hammond, A.C. Domest. Anim. Endocrinol. (1990) [Pubmed]
  25. Sarcocystis infection in pigs of Hissar, Haryana, India and its transmission to dogs. Gupta, S.L., Gautam, O.P. Vet. Parasitol. (1984) [Pubmed]
  26. Antibodies to Sarcocystis in Malaysians. Thomas, V., Dissanaike, A.S. Trans. R. Soc. Trop. Med. Hyg. (1978) [Pubmed]
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