MeSH Review:
Acantholysis
- Anti-cell surface pemphigus autoantibody stimulates plasminogen activator activity of human epidermal cells. A mechanism for the loss of epidermal cohesion and blister formation. Hashimoto, K., Shafran, K.M., Webber, P.S., Lazarus, G.S., Singer, K.H. J. Exp. Med. (1983)
- Spectrum of novel ATP2A2 mutations in patients with Darier's disease. Sakuntabhai, A., Burge, S., Monk, S., Hovnanian, A. Hum. Mol. Genet. (1999)
- Preferential activation of the complement system in the lower epidermis of patients with pemphigus vulgaris. Lapiere, J.C., Guitart, J., Ettlin, D.A., Chen, D.M., Amagai, M., Chan, L.S. Br. J. Dermatol. (1998)
- In vitro acantholysis by captopril and thiopronine. Ruocco, V., de Angelis, E., Lombardi, M.L., Pisani, M. Dermatologica (1988)
- Phosphatidylinositol-specific-phospholipase C cleaves urokinase plasminogen activator receptor from the cell surface and leads to inhibition of pemphigus-IgG-induced acantholysis in DJM-1 cells, a squamous cell carcinoma line. Asano, S., Seishima, M., Kitajima, Y. Clin. Exp. Dermatol. (2001)
- Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic. Amagai, M., Karpati, S., Prussick, R., Klaus-Kovtun, V., Stanley, J.R. J. Clin. Invest. (1992)
- Correlation of peptide specificity and IgG subclass with pathogenic and nonpathogenic autoantibodies in pemphigus vulgaris: a model for autoimmunity. Bhol, K., Natarajan, K., Nagarwalla, N., Mohimen, A., Aoki, V., Ahmed, A.R. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Novel mechanisms of target cell death and survival and of therapeutic action of IVIg in Pemphigus. Arredondo, J., Chernyavsky, A.I., Karaouni, A., Grando, S.A. Am. J. Pathol. (2005)
- Desmosome signaling. Inhibition of p38MAPK prevents pemphigus vulgaris IgG-induced cytoskeleton reorganization. Berkowitz, P., Hu, P., Liu, Z., Diaz, L.A., Enghild, J.J., Chua, M.P., Rubenstein, D.S. J. Biol. Chem. (2005)
- BALB/c mice produce blister-causing antibodies upon immunization with a recombinant human desmoglein 3. Fan, J.L., Memar, O., McCormick, D.J., Prabhakar, B.S. J. Immunol. (1999)
- Dexamethasone inhibits plasminogen activator activity in experimental pemphigus in vivo but does not block acantholysis. Anhalt, G.J., Patel, H.P., Labib, R.S., Diaz, L.A., Proud, D. J. Immunol. (1986)
- Effects of steroid, retinoid, and protease inhibitors on the formation of acantholysis induced in organ culture of skins from patients with benign familial chronic pemphigus. Ikeda, S., Ogawa, H. J. Invest. Dermatol. (1991)
- Methylprednisolone inhibits pemphigus acantholysis in skin cultures. Swanson, D.L., Dahl, M.V. J. Invest. Dermatol. (1983)
- Differential coupling of M1 muscarinic and alpha7 nicotinic receptors to inhibition of pemphigus acantholysis. Chernyavsky, A.I., Arredondo, J., Piser, T., Karlsson, E., Grando, S.A. J. Biol. Chem. (2008)
- Immunomorphologic and biochemical identification of the pemphigus foliaceous autoantigen within desmosomes. Rappersberger, K., Roos, N., Stanley, J.R. J. Invest. Dermatol. (1992)
- Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis. Schuh, T., Besch, R., Braungart, E., Flaig, M.J., Douwes, K., Sander, C.A., Magdolen, V., Probst, C., Wosikowski, K., Degitz, K. Biol. Chem. (2003)
- A mouse model of pemphigus vulgaris by adoptive transfer of naive splenocytes from desmoglein 3 knockout mice. Aoki-Ota, M., Tsunoda, K., Ota, T., Iwasaki, T., Koyasu, S., Amagai, M., Nishikawa, T. Br. J. Dermatol. (2004)
- Upregulation of P-cadherin expression in the lesional skin of pemphigus, Hailey-Hailey disease and Darier's disease. Hakuno, M., Akiyama, M., Shimizu, H., Wheelock, M.J., Nishikawa, T. J. Cutan. Pathol. (2001)
- Erythema multiforme associated human autoantibodies against desmoplakin I and II: biochemical characterization and passive transfer studies into newborn mice. Foedinger, D., Elbe-Bürger, A., Sterniczky, B., Lackner, M., Horvat, R., Wolff, K., Rappersberger, K. J. Invest. Dermatol. (1998)
- IgG binds to desmoglein 3 in desmosomes and causes a desmosomal split without keratin retraction in a pemphigus mouse model. Shimizu, A., Ishiko, A., Ota, T., Tsunoda, K., Amagai, M., Nishikawa, T. J. Invest. Dermatol. (2004)
- UVB-induced acantholysis in endemic Pemphigus foliaceus (Fogo selvagem) and Pemphigus vulgaris. Reis, V.M., Toledo, R.P., Lopez, A., Diaz, L.A., Martins, J.E. J. Am. Acad. Dermatol. (2000)
- Internalization of gap junctions in benign familial pemphigus (Hailey-Hailey disease) and keratosis follicularis (Darier's disease). Haftek, M., Kowalewski, C., Mesnil, M., Blaszczyk, M., Schmitt, D. Br. J. Dermatol. (1999)
- In vitro acantholysis induced by D-penicillamine, captopril, and piroxicam on dead de-epidermized dermis. De Dobbeleer, G., Godfrine, S., Gourdain, J.M., De Graef, C., Heenen, M. J. Cutan. Pathol. (1992)
- Differences in the expression of pemphigus antigens during epidermal differentiation. Iwatsuki, K., Harada, H., Yokote, R., Kaneko, F. Br. J. Dermatol. (1995)
- Internalization of constitutive desmogleins with the subsequent induction of desmoglein 2 in pemphigus lesions. Iwatsuki, K., Han, G.W., Fukuti, R., Ohtsuka, M., Kikuchi, S., Akiba, H., Kaneko, F. Br. J. Dermatol. (1999)
- Urokinase plasminogen activator mRNA is induced by IL-1alpha and TNF-alpha in in vitro acantholysis. Feliciani, C., Toto, P., Wang, B., Sauder, D.N., Amerio, P., Tulli, A. Exp. Dermatol. (2003)
- Induction of keratinocyte IL-8 expression and secretion by IgG autoantibodies as a novel mechanism of epidermal neutrophil recruitment in a pemphigus variant. O'Toole, E.A., Mak, L.L., Guitart, J., Woodley, D.T., Hashimoto, T., Amagai, M., Chan, L.S. Clin. Exp. Immunol. (2000)
- Fibronectin in pemphigus. Hunziker, T., Morgenthaler, J.J., Gerber, H.A. Dermatologica (1987)