Gene Review:
Asip - agouti signaling protein
Rattus norvegicus
Synonyms:
ASP, Agouti switch protein, Agouti-signaling protein
Sihvola,
Pulkkinen,
Koskinen,
Lemström,
Leibowitz,
Sepiashvili,
Akabayashi,
Karatayev,
Davydova,
Alexander,
Wang,
Chang,
O'Shea,
Easton,
Fry,
Green,
Marsden,
Harrold,
Williams,
Widdowson,
Korotkova,
Brown,
Sergeeva,
Ponomarenko,
Haas,
Lu,
Shieh,
Kabbaj,
Barsh,
Akil,
Watson,
Kas,
Bruijnzeel,
Haanstra,
Wiegant,
Adan,
Grove,
Allen,
Grayson,
Smith,
Dube,
Pu,
Kalra,
Kalra,
Romas,
Sims,
Hards,
Lindsay,
Quinn,
Ryan,
Dunstan,
Martin,
Gillespie,
Palmblad,
Erlandsson-Harris,
Tracey,
Andersson,
Vorhees,
Morford,
Inman,
Reed,
Schilling,
Cappon,
Moran,
Nebert,
- Thyroid hormone administration enhances remyelination in chronic demyelinating inflammatory disease. Fernandez, M., Giuliani, A., Pirondi, S., D'Intino, G., Giardino, L., Aloe, L., Levi-Montalcini, R., Calzà, L. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Decreased expression of liver glutathione peroxidase in Long-Evans cinnamon mutant rats predisposed to hepatitis and hepatoma. Suemizu, H., Yoshimura, S., Takeichi, N., Moriuchi, T. Hepatology (1994)
- Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and Agouti-related protein mRNA levels and body weight in rats. Kamegai, J., Tamura, H., Shimizu, T., Ishii, S., Sugihara, H., Wakabayashi, I. Diabetes (2001)
- Dynamics of early synovial cytokine expression in rodent collagen-induced arthritis : a therapeutic study using a macrophage-deactivating compound. Palmblad, K., Erlandsson-Harris, H., Tracey, K.J., Andersson, U. Am. J. Pathol. (2001)
- A possible role of neuropeptide Y, agouti-related protein and leptin receptor isoforms in hypothalamic programming by perinatal feeding in the rat. López, M., Seoane, L.M., Tovar, S., García, M.C., Nogueiras, R., Diéguez, C., Señarís, R.M. Diabetologia (2005)
- Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats. Tang-Christensen, M., Vrang, N., Ortmann, S., Bidlingmaier, M., Horvath, T.L., Tschöp, M. Endocrinology (2004)
- Dextrorotatory opioids induce stereotyped behavior in Sprague-Dawley and Dark Agouti rats. Ishmael, J.E., Franklin, P.H., Murray, T.F. Psychopharmacology (Berl.) (1998)
- Functional analysis of the Ala67Thr polymorphism in agouti related protein associated with anorexia nervosa and leanness. de Rijke, C.E., Jackson, P.J., Garner, K.M., van Rozen, R.J., Douglas, N.R., Kas, M.J., Millhauser, G.L., Adan, R.A. Biochem. Pharmacol. (2005)
- Differential regulation of agouti-related protein and neuropeptide Y in hypothalamic neurons following a stressful event. Kas, M.J., Bruijnzeel, A.W., Haanstra, J.R., Wiegant, V.M., Adan, R.A. J. Mol. Endocrinol. (2005)
- Glucose injection reduces neuropeptide Y and agouti-related protein expression in the arcuate nucleus: a possible physiological role in eating behavior. Chang, G.Q., Karatayev, O., Davydova, Z., Wortley, K., Leibowitz, S.F. Brain Res. Mol. Brain Res. (2005)
- The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis. Kawakami, N., Lassmann, S., Li, Z., Odoardi, F., Ritter, T., Ziemssen, T., Klinkert, W.E., Ellwart, J.W., Bradl, M., Krivacic, K., Lassmann, H., Ransohoff, R.M., Volk, H.D., Wekerle, H., Linington, C., Flügel, A. J. Exp. Med. (2004)
- N-acetylglucosaminyltransferase III and V messenger RNA levels in LEC rats during hepatocarcinogenesis. Miyoshi, E., Nishikawa, A., Ihara, Y., Gu, J., Sugiyama, T., Hayashi, N., Fusamoto, H., Kamada, T., Taniguchi, N. Cancer Res. (1993)
- Cytochrome P450 isozymes catalyzing 4-hydroxylation of parkinsonism-related compound 1,2,3,4-tetrahydroisoquinoline in rat liver microsomes. Suzuki, T., Fujita, S., Narimatsu, S., Masubuchi, Y., Tachibana, M., Ohta, S., Hirobe, M. FASEB J. (1992)
- Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis. Romas, E., Sims, N.A., Hards, D.K., Lindsay, M., Quinn, J.W., Ryan, P.F., Dunstan, C.R., Martin, T.J., Gillespie, M.T. Am. J. Pathol. (2002)
- Effects of chronic central nervous system administration of agouti-related protein in pair-fed animals. Small, C.J., Kim, M.S., Stanley, S.A., Mitchell, J.R., Murphy, K., Morgan, D.G., Ghatei, M.A., Bloom, S.R. Diabetes (2001)
- Ribavirin reduces clinical signs and pathological changes of experimental autoimmune encephalomyelitis in Dark Agouti rats. Milicevic, I., Pekovic, S., Subasic, S., Mostarica-Stojkovic, M., Stosic-Grujicic, S., Medic-Mijacevic, L., Pejanovic, V., Rakic, L., Stojiljkovic, M. J. Neurosci. Res. (2003)
- Glutamate ameliorates experimental vincristine neuropathy. Boyle, F.M., Wheeler, H.R., Shenfield, G.M. J. Pharmacol. Exp. Ther. (1996)
- Thyroid status regulates CART but not AgRP mRNA levels in the rat hypothalamus. López, M., Seoane, L., Tovar, S., Señarís, R.M., Diéguez, C. Neuroreport (2002)
- Function of neuropeptide Y and agouti-related protein at weaning: relation to corticosterone, dietary carbohydrate and body weight. Leibowitz, S.F., Sepiashvili, K., Akabayashi, A., Karatayev, O., Davydova, Z., Alexander, J.T., Wang, J., Chang, G.Q. Brain Res. (2005)
- Acute toxicity of 3,4-methylenedioxymethamphetamine (MDMA) in Sprague-Dawley and Dark Agouti rats. Malpass, A., White, J.M., Irvine, R.J., Somogyi, A.A., Bochner, F. Pharmacol. Biochem. Behav. (1999)
- Effects of arousal- and feeding-related neuropeptides on dopaminergic and GABAergic neurons in the ventral tegmental area of the rat. Korotkova, T.M., Brown, R.E., Sergeeva, O.A., Ponomarenko, A.A., Haas, H.L. Eur. J. Neurosci. (2006)
- Perhexiline-induced lipidosis in the dark Agouti (DA) rat. An animal model of genetically determined neurotoxicity. Meier, C., Wahllaender, A., Hess, C.W., Preisig, R. Brain (1986)
- Methoxyphenamine O-demethylase and 5-hydroxylase: a GLC-ECD assay to study their activities and their inhibition by debrisoquine and sparteine. Hawes, E.M., Roy, S.D., McKay, G., Midha, K.K. Pharmacol. Ther. (1987)
- Recombinant dimeric MHC antigens protect cardiac allografts from rejection and visualize alloreactive T cells. Fried, A., Berg, M., Sharma, B., Bonde, S., Zavazava, N. J. Leukoc. Biol. (2005)
- Altered expression of agouti-related protein and its colocalization with neuropeptide Y in the arcuate nucleus of the hypothalamus during lactation. Chen, P., Li, C., Haskell-Luevano, C., Cone, R.D., Smith, M.S. Endocrinology (1999)
- Butyrophilin, a milk protein, modulates the encephalitogenic T cell response to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis. Stefferl, A., Schubart, A., Storch2, M., Amini, A., Mather, I., Lassmann, H., Linington, C. J. Immunol. (2000)
- A C-terminal fragment of Agouti-related protein increases feeding and antagonizes the effect of alpha-melanocyte stimulating hormone in vivo. Rossi, M., Kim, M.S., Morgan, D.G., Small, C.J., Edwards, C.M., Sunter, D., Abusnana, S., Goldstone, A.P., Russell, S.H., Stanley, S.A., Smith, D.M., Yagaloff, K., Ghatei, M.A., Bloom, S.R. Endocrinology (1998)
- Distribution of galanin-like peptide in the rat brain. Takatsu, Y., Matsumoto, H., Ohtaki, T., Kumano, S., Kitada, C., Onda, H., Nishimura, O., Fujino, M. Endocrinology (2001)
- Abrogation of the immunosuppressive effect of donor spleen cells on renal allografts in the rat by irradiation or heat treatment. Cranston, D., Wood, K.J., Morris, P.J. Transplantation (1986)
- Protection against 3,4-methylenedioxymethamphetamine-induced neurodegeneration produced by glutathione depletion in rats is mediated by attenuation of hyperthermia. O'Shea, E., Easton, N., Fry, J.R., Green, A.R., Marsden, C.A. J. Neurochem. (2002)
- Genetic differences in spatial learning between Dark Agouti and Sprague-Dawley strains: possible correlation with the CYP2D2 polymorphism in rats treated neonatally with methamphetamine. Vorhees, C.V., Morford, L.L., Inman, S.L., Reed, T.M., Schilling, M.A., Cappon, G.D., Moran, M.S., Nebert, D.W. Pharmacogenetics (1999)
- Diurnal rhythm of agouti-related protein and its relation to corticosterone and food intake. Lu, X.Y., Shieh, K.R., Kabbaj, M., Barsh, G.S., Akil, H., Watson, S.J. Endocrinology (2002)
- Molecular basis of the Dark Agouti rat drug oxidation polymorphism: importance of CYP2D1 and CYP2D2. Yamamoto, Y., Tasaki, T., Nakamura, A., Iwata, H., Kazusaka, A., Gonzalez, F.J., Fujita, S. Pharmacogenetics (1998)
- Neuromedin s is a novel anorexigenic hormone. Ida, T., Mori, K., Miyazato, M., Egi, Y., Abe, S., Nakahara, K., Nishihara, M., Kangawa, K., Murakami, N. Endocrinology (2005)
- Postnatal development of the hypothalamic neuropeptide Y system. Grove, K.L., Allen, S., Grayson, B.E., Smith, M.S. Neuroscience (2003)
- Possible involvement of c-myc but not ras genes in hepatocellular carcinomas developing after spontaneous hepatitis in LEC rats. Fujimoto, Y., Ishizaka, Y., Tahira, T., Sone, H., Takahashi, H., Enomoto, K., Mori, M., Sugimura, T., Nagao, M. Mol. Carcinog. (1991)
- Agouti-related peptide prevents steroid-induced luteinizing hormone and prolactin surges in female rats. Schioth, H.B., Kakizaki, Y., Kohsaka, A., Suda, T., Watanobe, H. Neuroreport (2001)
- Changes in hypothalamic agouti-related protein (AGRP), but not alpha-MSH or pro-opiomelanocortin concentrations in dietary-obese and food-restricted rats. Harrold, J.A., Williams, G., Widdowson, P.S. Biochem. Biophys. Res. Commun. (1999)
- Ghrelin stimulates GH but not food intake in arcuate nucleus ablated rats. Tamura, H., Kamegai, J., Shimizu, T., Ishii, S., Sugihara, H., Oikawa, S. Endocrinology (2002)
- Agouti-related peptide, neuropeptide Y, and somatostatin-producing neurons are targets for ghrelin actions in the rat hypothalamus. Seoane, L.M., López, M., Tovar, S., Casanueva, F.F., Señarís, R., Diéguez, C. Endocrinology (2003)
- Damage of serotonergic axons and immunolocalization of Hsp27, Hsp72, and Hsp90 molecular chaperones after a single dose of MDMA administration in Dark Agouti rat: temporal, spatial, and cellular patterns. Adori, C., Andó, R.D., Kovács, G.G., Bagdy, G. J. Comp. Neurol. (2006)
- Melanocortin signaling is decreased during neurotoxin-induced transient hyperphagia and increased body-weight gain. Dube, M.G., Pu, S., Kalra, S.P., Kalra, P.S. Peptides (2000)
- Nitric oxide production during adjuvant-induced and collagen-induced arthritis. Cannon, G.W., Openshaw, S.J., Hibbs, J.B., Hoidal, J.R., Huecksteadt, T.P., Griffiths, M.M. Arthritis Rheum. (1996)
- Crosstalk of endothelin-1 and platelet-derived growth factor in cardiac allograft arteriosclerosis. Sihvola, R.K., Pulkkinen, V.P., Koskinen, P.K., Lemström, K.B. J. Am. Coll. Cardiol. (2002)
- Potential of allospecific gene-engineered T cells in transplantation gene therapy: specific T cell activation determines transgene expression in vitro and in vivo. Hammer, M.H., Flügel, A., Seifert, M., Lehmann, M., Brandt, C., Volk, H.D., Ritter, T. Hum. Gene Ther. (2000)
- Specific suppression of interleukin 2 biosynthesis by synthetic antisense oligodeoxynucleotides does not influence allograft rejection. Yun, S., Sawyer, G.J., Zhang, X., Gustafsson, K., Fabre, J.W. Transplantation (2000)
- A short course of cyclosporine immunosuppression inhibits rejection but not tolerance of rat liver allografts. Huang, W.H., Yan, Y., De Boer, B., Bishop, G.A., House, A.K. Transplantation (2003)