Disease relevance of Masticatory Muscles

• The findings of this study suggest that the soft splint is an effective short-term treatment for reducing the signs and symptoms of masticatory muscle pain in patients, and the soft splint does not cause occlusal changes [1].
• Both patients had parafunctional habits (bruxism), hypertrophic masticatory muscles, and wear of occlusal surfaces [2].
• AIM: To highlight the effectiveness of orthodontic treatment and bilateral equalization of the vertical occlusal dimension, along with the correction of asymmetric cervical and masticatory muscle activities in patients with Class III malocclusion with lateral deviation of the mandible and severely asymmetric condyle and ramus [3].
• Materials and Methods: In an randomized blinded placebo-controlled study, 90 patients (60 verum and 30 placebo) with chronic facial pain were treated with botulinum toxin type A (Botox; Allergan, Ettlingen, Germany) injections into masticatory muscles [4].
• There were 84 patients with clicking, 45 with headaches, 13 with neckaches, 39 with tenderness in the TMJ bilaterally and masticatory muscles and 12 with uncomfortable occlusal relationships [5].

Psychiatry related information on Masticatory Muscles

• The clinical dysfunction index of Helkimo and tenderness of the masticatory muscles on palpation were explainable, although to a minor degree, by the influence of a combination of age, occlusal interference, motor activity, and psychological factors [6].

High impact information on Masticatory Muscles

• It is conceivable that activation of peripheral NMDA receptors may contribute to masticatory muscle pain and that peripherally acting NMDA receptor antagonists could prove to be effective analgesics for this type of pain [7].
• The extent of proprioceptive deficiencies differed among different masticatory muscles, particularly in NT3 null mice [8].
• Complements of TMN neurons and masticatory muscle spindles were decreased by 62% in NT3 null mutants, 33% in BDNF null mutants, and 10% in NT4 null mutant mice at birth [8].
• Occlusal alterations may result in changes in the functional performance of masticatory muscles [9].
• In each treatment group, masticatory muscle injury was evaluated by contractile tension, plasma creatine kinase, and muscle glycogen [10].

Biological context of Masticatory Muscles

• Influence of stress and occlusal interference on the EMG activity of some masticatory muscles during a single mastication cycle [11].
• The aims of this study were (1) to investigate the relationship between occlusal factors and masticatory muscle tenderness among 10- to 19-year-old (mean 14 years eight months) Turkish subjects and (2) to identify possible sex differences between them [12].
• Based on the result, early occlusal improvement, combined with orthopedic surgery of the neck muscles or physiotherapy to achieve muscular balance of the neck and masticatory muscles, was found to be effective [13].
• Functional appliance therapy was instituted in an 11 year, 7 month old boy with hemifacial microsomia in order to determine if symmetry could be re-established by promoting masticatory muscle function on the affected side, thereby stimulating bone growth in the affected condyle over and above what would occur without any treatment intervention [14].
• The asymmetric condylar movements are reflected in the asymmetry of the muscular contractions, put into evidence through the insufficient response to AROM (78%), PROM (62%), resistive muscle tests (8%) for the masticatory muscles and cervical spine (22%) [15].

Anatomical context of Masticatory Muscles

• Characteristics of the muscle spindle endings of the masticatory muscles in the rabbit under halothane anesthesia [16].
• The phosphorylated Extracellular Signal-regulated Kinase (pERK) and Fos expression and masticatory muscle activity were analyzed in rats with capsaicin-induced acute inflammation of the tooth pulp in order to clarify the role of the spinal trigeminal nucleus and upper cervical spinal cord in tooth pulp pain [17].
• Contrary to the limb skeleton no causal relationship between the histological structure of the tendon entheses and the osteogenic mode of the bone areas involved was observed in the masticatory muscles that were studied [18].
• A comprehensive set of clinical examinations was performed, including occlusal analysis and examination of masticatory muscle and TMJ [19].
• Dopamine neurons in the nigrostriatal subgroup of the basal ganglia are involved in the higher control of muscle tone and repetitive movements, possibly also in the masticatory muscles [20].

Associations of Masticatory Muscles with chemical compounds

• Effects of NK433, a new centrally acting muscle relaxant, on masticatory muscle reflexes in rats [21].
• MRS assessment of glutamate clearance in a novel masticatory muscle pain model [22].
• These findings indicate that histamine is involved in the sensory regulation of movement of the masticatory muscles at the level of the trigeminal mesencephalic nucleus [23].
• To elucidate the effects of succinylcholine on masticatory muscle function, mouth opening in the cat, produced by a constant test force, was measured during steady state halothane anesthesia [24].
• Salivary cortisol level, salivary flow rate, and masticatory muscle activity in response to acute mental stress: a comparison between aged and young women [25].

Gene context of Masticatory Muscles

• Intermuscular and intramuscular differences in myosin heavy chain composition of the human masticatory muscles [26].
• The fact that some subjects did develop masticatory muscle pain is indicative that muscle exercise and fatigue may lead to TMD-like symptoms [27].
• Innervation of facial skin but not masticatory muscles or the tongue by trigeminal primary afferents containing somatostatin in the rat [28].
• However, the interleukin-6 level was less than 100 U/mL (range, 20 to 75 U/mL) in all patients with masticatory muscle disorder [29].
• The Krox-20 null mutation differentially affects the development of masticatory muscles [30].

Analytical, diagnostic and therapeutic context of Masticatory Muscles

• Histologic changes in rat masticatory muscles subsequent to experimental increase of the occlusal vertical dimension [31].
• The diclofenac group also showed a significant decrease in tenderness to palpation of the masticatory muscles in comparison with the placebo group [32].
• Electromyography of masticatory muscles has proved useful for the functional study of occlusal dysfunctions [33].
• Transcutaneous electrical nerve stimulation therapy relaxed masticatory muscles and aided in the determination of a therapeutic occlusal position [34].
• The purpose of this study was to investigate occlusal schemes (canine guidance and group function) in relation to masticatory muscle activity [35].

References