Disease relevance of Priapism

• Acute priapism associated with the use of sildenafil in a patient with sickle cell trait [1].
• Available data also suggest that nefazodone is not associated with abnormal weight gain, seizures, priapism or significant sleep disruption, and appears to be relatively safe in overdosage [2].
• Stuttering priapism associated with withdrawal from sustained-release methylphenidate [3].
• Papaverine in combination with phentolamine is effective, but penile fibrosis and priapism occur more often than with the use of alprostadil [4].
• Testosterone induced priapism in Kallmann's syndrome [5].

Psychiatry related information on Priapism

• Prostaglandin E1 in erectile dysfunction. Efficiency and incidence of priapism [6].

High impact information on Priapism

• Priapism related to phenelzine therapy [7].
• Treatment of partial priapism with an intracavernous injection of etilefrine [8].
• Priapism in patient on tamoxifen [9].
• Metaraminol for haemodialysis-associated priapism [10].
• Trazodone associated with priapism [11].

Chemical compound and disease context of Priapism

• Metaraminol for priapism [12].
• Thus, aspiration of the corpora cavernosa followed by irrigation with dilute epinephrine is effective in producing immediate and sustained detumescence and should be the initial therapy employed for patients with SCA and prolonged priapism [13].
• Priapism associated with chronic cocaine abuse [14].
• Phenothiazine-induced priapism: a case report [15].
• Priapism following testosterone administration for delayed male puberty [16].
• We report a case of priapism specifically associated with terazosin prescribed for lower urinary tract symptoms in an otherwise healthy man [17].

Biological context of Priapism

• Heterotopic bone formation in the corpus cavernosum: a complication of papaverine-induced priapism [18].
• PURPOSE: We identify whether tachyphylaxis and priapism effects of sildenafil are related to regulation of phosphodiesterase-5 (PDE-5) expression [19].
• Presented is a case of idiopathic priapism that was successfully treated with inhalation of amyl nitrite [20].
• RESULTS: The Thought Leader Panel recommended adoption of the definition of priapism as a pathological condition of a penile erection that persists beyond or is unrelated to sexual stimulation [21].
• The association between heparin and priapism is often recognized; abnormal platelet aggregation could play a role in the pathogenesis of this side effect [22].

Anatomical context of Priapism

• Heparin-induced antiplatelet-antibodies may lead to the aggregation of thrombocytes and thus alter the penile blood flow leading to low-flow priapism [23].

Gene context of Priapism

• In addition, male clusters differed significantly for percent ever having had pneumonia, priapism, or dactylitis, and females differed significantly for height and weight. %Hb F and its inverse relationship with %HBA2 was more highly associated with the measures of severity than the degree of anemia or MCV [24].
• Priapism caused by glucose phosphate isomerase deficiency [25].
• Priapism revealing ARG 506 to GLN factor V mutation [26].
• Successful treatment of recalcitrant priapism using intercorporeal injection of tissue plasminogen activator [27].
• To our knowledge, this is the first such report of stuttering priapism associated with stimulant drugs for treatment of attention deficit hyperactivity disorder [3].

Analytical, diagnostic and therapeutic context of Priapism

• During the 8 years since inception of a home total parenteral nutrition program in 35 male patients 2 suffered priapism related temporally to the weekly intravenous infusion of 20 per cent fat emulsion [28].
• Evaluations involved a medical history and physical examination with completion of priapism and sexual function questionnaires, followed by NPT/PSG and MRI of the penis [29].
• This is the first report of a male hemodialysis patient experiencing recurrent dialysis-associated priapism that resolved when his concurrent erythropoietin dose was reduced from 2000 to 1500 U one time per week and held if his hemoglobin was greater than 10 g/dL [30].
• The use of heparin during dialysis seemed to play a role in its induction; none of the patients on peritoneal dialysis experienced priapism, and heparin was not used in their exchanges [31].
• Prazosin induced priapism in a patient on continuous ambulatory peritoneal dialysis (CAPD) [32].

References