Disease relevance of Encephalitis, Viral

• We studied soluble ICAM-1 concentrations in patients with multiple sclerosis (MS), viral encephalitis, and other immunologic diseases, and compared results with those in other noninflammatory, nondemyelinating neurologic disorders as well as in healthy controls [1].
• Although patients with viral encephalitis had higher mean neopterin levels than any other patient category studied, the CSF neopterin concentrations cannot be used to discriminate between viral and bacterial infections [2].
• The serum IgA level was elevated in all five lesions, but the IgA level in CSF was elevated only in viral encephalitis, Guillain-Barré syndrome, and meningeal carcinomatosis.(ABSTRACT TRUNCATED AT 250 WORDS)[3]
• Five patients had documented infection (typhoid fever 2; systemic candidiasis 1; adenovirus pneumonia 1; viral encephalitis 1), and two had systemic lupus erythematosus [4].
• The protective effect of pretreatment with dehydroepiandrosterone (DHEA) on stress-enhanced viral encephalitis was studied in mice exposed to cold following inoculation with West Nile virus (WNV) [5].

Psychiatry related information on Encephalitis, Viral

• This study evaluated effects of a checklist on the accuracy of self-assessment of blood glucose level by a diabetic woman with memory impairments caused by viral encephalitis [6].
• This report presents a case which along with emerging symptoms of Kluver-Bucy syndrome, developed Attention-Deficit/Hyperactivity Disorder (ADHD) consequent to viral encephalitis [7].

High impact information on Encephalitis, Viral

• At the time of increased CSF protein concentration during an acute viral encephalitis these differences were narrowed but not eliminated [8].
• Vidarabine monophosphate in viral encephalitis [9].
• Isoprinosine in treatment of acute viral encephalitis [10].
• In 32 (70%) of 46 MS patients, 8 (80%) of 10 patients with acute viral encephalitis, but none of the control subjects with noninflammatory diseases, gadolinium-enhancing lesions were detected [11].
• There were more numerous ICAM-1-positive vessels in active MS plaque edges, viral encephalitis lesions, infarcts, and in six controls [12].

Chemical compound and disease context of Encephalitis, Viral

• High-dose benzodiazepine therapy and a history of viral encephalitis may be risk factors for withdrawal delirium [13].
• The demonstration that NMDA receptors and NO are involved in granule-mediated killing of mature neurons opens new avenues in the treatment of neuronal cell death in CTL-mediated diseases such as viral encephalitis [14].
• To define the clinical characteristics of acyclovir neurotoxicity and to outline how to distinguish it from viral encephalitis [15].
• Cerebral serotonin in viral encephalitis [16].
• Viral encephalitis in children: detection with technetium-99m HMPAO brain single-photon emission CT and its value in prediction of outcome [17].

Biological context of Encephalitis, Viral

• These results strongly suggest that, the modulation of TNF-alpha and upregulation of IFN-gamma would be a powerful anti-virus strategy in cases of viral encephalitis [18].
• Innate immunity in viral encephalitis: role of C5 [19].
• Immunosuppression with cyclophosphamide (CPA) affected the course of the infection when a higher dose (10(6) suckling mouse intracerebral LD50) of the virus and 2 or 3 injections of CPA (150 mg/kg each) were given: then a part of the animals died due to viral encephalitis, whereas all the CPA-untreated infected mice survived [20].
• This study evaluates the comorbidity of epilepsy as a variable supporting a viral hypothesis in Autism. Data covering a 30-year period (1960-1989), including general population live births, autistic births, and incidence of viral encephalitis and viral meningitis, were collected for Israel. 290 autistic births were evaluated [21].

Anatomical context of Encephalitis, Viral

• The brain B-lymphocyte population correlated well with CD4 T-lymphocyte level in the blood, in cases with viral encephalitis [22].

Gene context of Encephalitis, Viral

• Interleukin (IL)-12 receptor beta1 or IL-12 receptor beta 2 deficiency in mice indicates that IL-12 and IL-23 are not essential for host recovery from viral encephalitis [23].
• Selective role for the p55 Kd TNF-alpha receptor in immune unresponsiveness induced by an acute viral encephalitis [24].
• Viral encephalitis showed the highest mean S100B levels (mean 0.58 microg/l) [25].
• Results in the 6 patients with acute viral encephalitis suggested that the CD8+ population in the CSF which is positive for CD28 and CD45RO is important for the elimination of virus from infected CNS tissues [26].
• IgG levels in CSF and serum were elevated in all five infections studied except viral encephalitis, in which this value remained normal [3].

Analytical, diagnostic and therapeutic context of Encephalitis, Viral

• Retrospective testing of 833 sera from New York patients with suspected viral encephalitis demonstrated concordance with results obtained with the traditional enzyme-linked immunosorbent assay for immunoglobulin G (IgG) antibodies to WN virus (kappa = 0.85) [27].
• Therapy of focal viral encephalitis in children with aciclovir and recombinant beta-interferon - results of a placebo-controlled multicenter study [28].

References