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MeSH Review

Sierra Leone

 
 
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Disease relevance of Sierra Leone

 

High impact information on Sierra Leone

  • The antiprotozoal compound 1,5-di(4-amidinophenoxy)pentane (pentamidine) and 36 of its analogs were screened for in vitro activity against Leishmania mexicana amazonensis clone 669 C4S (MHOM/BR/73/M2269) and Plasmodium falciparum clones W2 (Indochina III/CDC) and D6 (Sierra Leone I/CDC) [6].
  • Fourteen Sierra Leone M. africanum isolates (designated group A) had katG codon 203 ACC Thr, also found in M. africanumT (the T indicates type strain) from Senegal [7].
  • The transmission resulting from the reinvasion of northern Côte d'Ivoire and Burkina Faso has been reduced by over 95%, but eastern Mali has proved more difficult to protect because of sources in both Guinea and Sierra Leone [8].
  • A controlled trial of lambda-cyhalothrin-impregnated bed nets and/or dapsone/pyrimethamine for malaria control in Sierra Leone [9].
  • Disequilibria in the distribution of rpoB alleles in rifampicin-resistant M. tuberculosis isolates from Germany and Sierra Leone [10].
 

Chemical compound and disease context of Sierra Leone

 

Biological context of Sierra Leone

 

Associations of Sierra Leone with chemical compounds

  • Fatal parathion poisoning in Sierra Leone [13].
  • Albendazole therapy and reduced decline in haemoglobin concentration during pregnancy (Sierra Leone) [14].
  • Evidence basis for antimalarial policy change in Sierra Leone: five in vivo efficacy studies of chloroquine, sulphadoxine-pyrimethamine and amodiaquine [15].
  • OBJECTIVES: To provide nationally relevant information on the antimalarial efficacy of chloroquine (CQ), sulphadoxine-pyrimethamine (SP) and amodiaquine (AQ) in Sierra Leone, with a view to updating antimalarial policy in the country [15].
  • DESIGN/SETTING: From September to December of 1994, semi-structured interviews were conducted with 72 patients and 17 staff of the National Leprosy and Tuberculosis Control Programme of Sierra Leone, a screening and treatment programme funded by international donors [16].
 

Gene context of Sierra Leone

  • In this report, SM resistance associated mutations in the rrs and rpsL genes of 25 SM resistant isolates from Germany and 25 SM resistant isolates from Sierra Leone were characterized and compared [17].
  • DESIGN: Codons 94 and 95 in the inhA gene and codons 315 and 463 in the katG gene were characterized in 50 INH-resistant and 12 INH-sensitive isolates from Germany and Sierra Leone [18].
  • From December 1999 to the end of February 2000, 4218 cases of dysentery were reported in Kenema district, southeastern Sierra Leone, by a Médecins Sans Frontières team operating in this region [19].
  • This study showed that it is possible to run an effective intervention for neuropathic pain in Sierra Leone with intermittent expert involvement and MSF have been able to develop a protocol for the assessment and treatment of neuropathic pain that may be useful in other difficult settings in which they work [20].
  • This paper reviews 100 years of malaria field research and control in Sierra Leone, which became known as the 'White Man's Grave' in the 19th century largely because of the high malaria-related mortality amongst Europeans living there [21].
 

Analytical, diagnostic and therapeutic context of Sierra Leone

References

  1. Side-effects of ivermectin in treatment of onchocerciasis. Rothova, A., van der Lelij, A., Stilma, J.S., Wilson, W.R., Barbe, R.F. Lancet (1989) [Pubmed]
  2. Sensitive radioimmunoassay for the broad-spectrum antiviral agent ribavirin. Austin, R.K., Trefts, P.E., Hintz, M., Connor, J.D., Kagnoff, M.F. Antimicrob. Agents Chemother. (1983) [Pubmed]
  3. Cluster of chloroquine-resistant Plasmodium falciparum malaria cases among short-term travellers to Sierra Leone. Lackritz, E.M., Adamson, R., Williams, S., Roof, R. Trans. R. Soc. Trop. Med. Hyg. (1990) [Pubmed]
  4. Povidone-iodine (betadine) in the treatment of experimental Pseudomonas aeruginosa keratitis. Michalová, K., Moyes, A.L., Cameron, S., Juni, B.A., Obritsch, W.F., Dvorak, J.A., Doughman, D.J., Rhame, F.S. Cornea (1996) [Pubmed]
  5. Identification and characterization of a parasite antigen in the circulating immune complexes of Onchocerca volvulus infected patients. Thambiah, G., Whitworth, J., Hommel, M., Devaney, E. Trop. Med. Parasitol. (1992) [Pubmed]
  6. Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis. Bell, C.A., Hall, J.E., Kyle, D.E., Grogl, M., Ohemeng, K.A., Allen, M.A., Tidwell, R.R. Antimicrob. Agents Chemother. (1990) [Pubmed]
  7. Phenotypic and genotypic characterization of Mycobacterium africanum isolates from West Africa. Frothingham, R., Strickland, P.L., Bretzel, G., Ramaswamy, S., Musser, J.M., Williams, D.L. J. Clin. Microbiol. (1999) [Pubmed]
  8. Progress in controlling the reinvasion of windborne vectors into the western area of the Onchocerciasis Control Programme in West Africa. Baker, R.H., Guillet, P., Sékétéli, A., Poudiougo, P., Boakye, D., Wilson, M.D., Bissan, Y. Philos. Trans. R. Soc. Lond., B, Biol. Sci. (1990) [Pubmed]
  9. A controlled trial of lambda-cyhalothrin-impregnated bed nets and/or dapsone/pyrimethamine for malaria control in Sierra Leone. Marbiah, N.T., Petersen, E., David, K., Magbity, E., Lines, J., Bradley, D.J. Am. J. Trop. Med. Hyg. (1998) [Pubmed]
  10. Disequilibria in the distribution of rpoB alleles in rifampicin-resistant M. tuberculosis isolates from Germany and Sierra Leone. Rinder, H., Dobner, P., Feldmann, K., Rifai, M., Bretzel, G., Rüsch-Gerdes, S., Löscher, T. Microb. Drug Resist. (1997) [Pubmed]
  11. Onchocerciasis distribution and severity in five West African countries. De Sole, G., Baker, R., Dadzie, K.Y., Giese, J., Guillet, P., Keita, F.M., Remme, J. Bull. World Health Organ. (1991) [Pubmed]
  12. Antibodies against arboviruses in Sierra Leone. Tomori, O., Fabiyi, A. Tropical and geographical medicine. (1976) [Pubmed]
  13. Fatal parathion poisoning in Sierra Leone. Etzel, R.A., Forthal, D.N., Hill, R.H., Demby, A. Bull. World Health Organ. (1987) [Pubmed]
  14. Albendazole therapy and reduced decline in haemoglobin concentration during pregnancy (Sierra Leone). Torlesse, H., Hodges, M. Trans. R. Soc. Trop. Med. Hyg. (2001) [Pubmed]
  15. Evidence basis for antimalarial policy change in Sierra Leone: five in vivo efficacy studies of chloroquine, sulphadoxine-pyrimethamine and amodiaquine. Checchi, F., Roddy, P., Kamara, S., Williams, A., Morineau, G., Wurie, A.R., Hora, B., Lamotte, N., Baerwaldt, T., Heinzelmann, A., Danks, A., Pinoges, L., Oloo, A., Durand, R., Ranford-Cartwright, L., Smet, M. Trop. Med. Int. Health (2005) [Pubmed]
  16. The cost of tuberculosis to patients in Sierra Leone's war zone. Gibson, N., Boillot, F., Jalloh, H. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. (1998) [Pubmed]
  17. Geographic variation of the predictive values of genomic mutations associated with streptomycin resistance in Mycobacterium tuberculosis. Dobner, P., Bretzel, G., Rüsch-Gerdes, S., Feldmann, K., Rifai, M., Löscher, T., Rinder, H. Mol. Cell. Probes (1997) [Pubmed]
  18. Usefulness of Mycobacterium tuberculosis genomic mutations in the genes katG and inhA for the prediction of isoniazid resistance. Dobner, P., Rüsch-Gerdes, S., Bretzel, G., Feldmann, K., Rifai, M., Löscher, T., Rinder, H. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. (1997) [Pubmed]
  19. Case management of a multidrug-resistant Shigella dysenteriae serotype 1 outbreak in a crisis context in Sierra Leone, 1999-2000. Guerin, P.J., Brasher, C., Baron, E., Mic, D., Grimont, F., Ryan, M., Aavitsland, P., Legros, D. Trans. R. Soc. Trop. Med. Hyg. (2004) [Pubmed]
  20. Field research in humanitarian medical programmes. Treatment of neuropathic pain in Sierra Leone. Lacoux, P.A., Lassalle, X., McGoldrick, P.M., Crombie, I.K., Macrae, W.A. Trans. R. Soc. Trop. Med. Hyg. (2003) [Pubmed]
  21. It all began with Ronald Ross: 100 years of malaria research and control in Sierra Leone (1899-1999). Bockarie, M.J., Gbakima, A.A., Barnish, G. Ann. Trop. Med. Parasitol. (1999) [Pubmed]
  22. Comparison of albendazole and levamisole chemotherapy on prevalence and intensity of common soil-transmitted helminth infections in school children, Sierra Leone. Williams, R.A., Koroma, M.M., Hodges, M. West African journal of medicine. (1997) [Pubmed]
  23. Animal health survey of cattle for the Bombali region, Sierra Leone, 1977. Hassan, I.C. Beiträge zur tropischen Landwirtschaft und Veterinärmedizin. (1979) [Pubmed]
 
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