Gene Review:
katG - catalase-peroxidase
Mycobacterium tuberculosis H37Rv
Kremer,
Dover,
Morbidoni,
Vilchèze,
Maughan,
Baulard,
Tu,
Honoré,
Deretic,
Sacchettini,
Locht,
Jacobs,
Besra,
Höfling,
Pavan,
Giampaglia,
Ferrazoli,
Aily,
de Albuquerque,
Ramos,
van Doorn,
de Haas,
Kremer,
Vandenbroucke-Grauls,
Borgdorff,
van Soolingen,
Caws,
Duy,
Tho,
Lan,
Hoa,
Farrar,
Rinder,
Mieskes,
Löscher,
Herrera-León,
Molina,
Saíz,
Sáez-Nieto,
Jiménez,
Wojtyczka,
Dworniczak,
Pacha,
Idzik,
Kepa,
Wydmuch,
Głab,
Bajorek,
Oklek,
Kozielski,
- Performance of the Genotype MTBDR Line Probe Assay for Detection of Resistance to Rifampin and Isoniazid in Strains of Mycobacterium tuberculosis with Low- and High-Level Resistance. Brossier, F., Veziris, N., Truffot-Pernot, C., Jarlier, V., Sougakoff, W. J. Clin. Microbiol. (2006)
- Detection of Multidrug Resistance in Mycobacterium tuberculosis. Sekiguchi, J., Miyoshi-Akiyama, T., Augustynowicz-Kopec, E., Zwolska, Z., Kirikae, F., Toyota, E., Kobayashi, I., Morita, K., Kudo, K., Kato, S., Kuratsuji, T., Mori, T., Kirikae, T. J. Clin. Microbiol. (2007)
- PCR-RFLP analysis of a point mutation in codons 315 and 463 of the katG gene of Mycobacterium tuberculosis isolated from patients in Silesia, Poland. Wojtyczka, R.D., Dworniczak, S., Pacha, J., Idzik, D., Kepa, M., Wydmuch, Z., Głab, S., Bajorek, M., Oklek, K., Kozielski, J. Pol. J. Microbiol. (2004)
- Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: a molecular study. Heym, B., Honoré, N., Truffot-Pernot, C., Banerjee, A., Schurra, C., Jacobs, W.R., van Embden, J.D., Grosset, J.H., Cole, S.T. Lancet (1994)
- Structure and mechanism of the alkyl hydroperoxidase AhpC, a key element of the Mycobacterium tuberculosis defense system against oxidative stress. Guimarães, B.G., Souchon, H., Honoré, N., Saint-Joanis, B., Brosch, R., Shepard, W., Cole, S.T., Alzari, P.M. J. Biol. Chem. (2005)
- Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria. Kremer, L., Dover, L.G., Morbidoni, H.R., Vilchèze, C., Maughan, W.N., Baulard, A., Tu, S.C., Honoré, N., Deretic, V., Sacchettini, J.C., Locht, C., Jacobs, W.R., Besra, G.S. J. Biol. Chem. (2003)
- Role of KatG catalase-peroxidase in mycobacterial pathogenesis: countering the phagocyte oxidative burst. Ng, V.H., Cox, J.S., Sousa, A.O., MacMicking, J.D., McKinney, J.D. Mol. Microbiol. (2004)
- Regulation of catalase-peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis. Pym, A.S., Domenech, P., Honoré, N., Song, J., Deretic, V., Cole, S.T. Mol. Microbiol. (2001)
- Lack of clinical significance for the common arginine-to-leucine substitution at codon 463 of the katG gene in isoniazid-resistant Mycobacterium tuberculosis in Singapore. Lee, A.S., Tang, L.L., Lim, I.H., Ling, M.L., Tay, L., Wong, S.Y. J. Infect. Dis. (1997)
- Public health impact of isoniazid-resistant Mycobacterium tuberculosis strains with a mutation at amino-acid position 315 of katG: a decade of experience in The Netherlands. van Doorn, H.R., de Haas, P.E., Kremer, K., Vandenbroucke-Grauls, C.M., Borgdorff, M.W., van Soolingen, D. Clin. Microbiol. Infect. (2006)
- Genotypic Analysis of Multidrug-Resistant Mycobacterium tuberculosis Isolates Recovered From Central China. Zhang, S.L., Qi, H., Qiu, D.L., Li, D.X., Zhang, J., Du, C.M., Wang, G.B., Yang, Z.R., Sun, Q. Biochem. Genet. (2007)
- Mutations in the rpoB and katG genes leading to drug resistance in Mycobacterium tuberculosis in Latvia. Tracevska, T., Jansone, I., Broka, L., Marga, O., Baumanis, V. J. Clin. Microbiol. (2002)
- Dual-probe assay for rapid detection of drug-resistant Mycobacterium tuberculosis by real-time PCR. Wada, T., Maeda, S., Tamaru, A., Imai, S., Hase, A., Kobayashi, K. J. Clin. Microbiol. (2004)
- New multiplex PCR for rapid detection of isoniazid-resistant Mycobacterium tuberculosis clinical isolates. Herrera-León, L., Molina, T., Saíz, P., Sáez-Nieto, J.A., Jiménez, M.S. Antimicrob. Agents Chemother. (2005)
- The genetics and biochemistry of isoniazid resistance in mycobacterium tuberculosis. Slayden, R.A., Barry, C.E. Microbes Infect. (2000)
- Population genetics study of isoniazid resistance mutations and evolution of multidrug-resistant Mycobacterium tuberculosis. Hazbón, M.H., Brimacombe, M., Bobadilla del Valle, M., Cavatore, M., Guerrero, M.I., Varma-Basil, M., Billman-Jacobe, H., Lavender, C., Fyfe, J., García-García, L., León, C.I., Bose, M., Chaves, F., Murray, M., Eisenach, K.D., Sifuentes-Osornio, J., Cave, M.D., Ponce de León, A., Alland, D. Antimicrob. Agents Chemother. (2006)
- Mutations prevalent among rifampin- and isoniazid-resistant Mycobacterium tuberculosis isolates from a hospital in Vietnam. Caws, M., Duy, P.M., Tho, D.Q., Lan, N.T., Hoa, D.V., Farrar, J. J. Clin. Microbiol. (2006)
- Molecular characterization of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis from the USA. Guo, H., Seet, Q., Denkin, S., Parsons, L., Zhang, Y. J. Med. Microbiol. (2006)
- Heteroresistance in Mycobacterium tuberculosis. Rinder, H., Mieskes, K.T., Löscher, T. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. (2001)
- Presence of katG gene in resistant Mycobacterium tuberculosis. Jaber, M., Rattan, A., Kumar, R. J. Clin. Pathol. (1996)
- Association between Mycobacterium tuberculosis Beijing/W Lineage Strain Infection and Extrathoracic Tuberculosis: Insights from Epidemiologic and Clinical Characterization of the Three Principal Genetic Groups of M. tuberculosis Clinical Isolates. Kong, Y., Cave, M.D., Zhang, L., Foxman, B., Marrs, C.F., Bates, J.H., Yang, Z.H. J. Clin. Microbiol. (2007)
- Detection of resistance to isoniazid, rifampin, and streptomycin in clinical isolates of Mycobacterium tuberculosis by molecular methods. Nachamkin, I., Kang, C., Weinstein, M.P. Clin. Infect. Dis. (1997)
- Molecular characterization of isoniazid-resistant Mycobacterium tuberculosis isolates collected in Australia. Lavender, C., Globan, M., Sievers, A., Billman-Jacobe, H., Fyfe, J. Antimicrob. Agents Chemother. (2005)
- Rapid genotypic detection of rifampin- and isoniazid-resistant Mycobacterium tuberculosis directly in clinical specimens. Bang, D., Bengård Andersen, A., Thomsen, V.Ø. J. Clin. Microbiol. (2006)
- Molecular analysis of isoniazid resistance in Mycobacterium tuberculosis isolates recovered from South Korea. Kim, S.Y., Park, Y.J., Kim, W.I., Lee, S.H., Ludgerus Chang, C., Kang, S.J., Kang, C.S. Diagn. Microbiol. Infect. Dis. (2003)
- Prevalence of katG Ser315 substitution and rpoB mutations in isoniazid-resistant Mycobacterium tuberculosis isolates from Brazil. Höfling, C.C., Pavan, E.M., Giampaglia, C.M., Ferrazoli, L., Aily, D.C., de Albuquerque, D.M., Ramos, M.C. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. (2005)
- Strain variation in the katG region of Mycobacterium tuberculosis. Zhang, Y., Young, D. Mol. Microbiol. (1994)
- Effect of katG mutations on the virulence of Mycobacterium tuberculosis and the implication for transmission in humans. Pym, A.S., Saint-Joanis, B., Cole, S.T. Infect. Immun. (2002)