Gene Review:
HLA-DQA1 - major histocompatibility complex, class II...
Homo sapiens
Synonyms:
CD, CELIAC1, DC-1 alpha chain, DC-alpha, DQ-A1, ...
Yucel,
Ozbey,
Demir,
Polat,
Yager,
Slatkin,
Muirhead,
Maffei,
Harris,
Reed,
Del Pozzo,
Ciullo,
Suciu-Foca,
Guardiola,
Agardh,
Roth,
Lernmark,
Stenberg,
Buc,
Bucová,
Javor,
Krivosíkova,
Stuchlíkova,
Shawkatova,
Michalková,
Barák,
Jancová,
Petrek,
Anderson,
Degano,
Godkin,
Jewell,
Hill,
Sollid,
Garrote,
Arranz,
Blanco-Quirós,
- HLA-DQA1*1 contributes to resistance and A1*3 confers susceptibility to type 1 (insulin-dependent) diabetes mellitus in Japanese subjects. Yamagata, K., Hanafusa, T., Nakajima, H., Sada, M., Amemiya, H., Noguchi, T., Tanaka, T., Kono, N., Tarui, S. Diabetologia (1991)
- DNA sequence analysis and restriction fragment length polymorphism (RFLP) typing of the HLA-DQw2 alleles associated with dermatitis herpetiformis. Otley, C.C., Wenstrup, R.J., Hall, R.P. J. Invest. Dermatol. (1991)
- HLA-DQA1 and HLA-DQB1 genes may jointly determine susceptibility to develop multiple sclerosis. Spurkland, A., Rønningen, K.S., Vandvik, B., Thorsby, E., Vartdal, F. Hum. Immunol. (1991)
- HLA-DQA1, -DQB1 and -DRB1 genotyping in Japanese pemphigus vulgaris patients by the PCR-RFLP method. Niizeki, H., Inoko, H., Mizuki, N., Inamoto, N., Watababe, K., Hashimoto, T., Nishikawa, T. Tissue Antigens (1994)
- Susceptibility and resistance alleles of human leukocyte antigen (HLA) DQA1 and HLA DQB1 are shared in endocrine autoimmune disease. Badenhoop, K., Walfish, P.G., Rau, H., Fischer, S., Nicolay, A., Bogner, U., Schleusener, H., Usadel, K.H. J. Clin. Endocrinol. Metab. (1995)
- Forensic application of a rapid and quantitative DNA sex test by amplification of the X-Y homologous gene amelogenin. Mannucci, A., Sullivan, K.M., Ivanov, P.L., Gill, P. Int. J. Legal Med. (1994)
- Celiac disease, brain atrophy, and dementia. Collin, P., Pirttilä, T., Nurmikko, T., Somer, H., Erilä, T., Keyriläinen, O. Neurology (1991)
- Eating disorders and celiac disease: a case report. Yucel, B., Ozbey, N., Demir, K., Polat, A., Yager, J. The International journal of eating disorders. (2006)
- Molecular basis of celiac disease. Sollid, L.M. Annu. Rev. Immunol. (2000)
- An autosomal screen for genes that predispose to celiac disease in the western counties of Ireland. Zhong, F., McCombs, C.C., Olson, J.M., Elston, R.C., Stevens, F.M., McCarthy, C.F., Michalski, J.P. Nat. Genet. (1996)
- Maternal-fetal disparity in HLA class II alloantigens and the pregnancy-induced amelioration of rheumatoid arthritis. Nelson, J.L., Hughes, K.A., Smith, A.G., Nisperos, B.B., Branchaud, A.M., Hansen, J.A. N. Engl. J. Med. (1993)
- In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope. Anderson, R.P., Degano, P., Godkin, A.J., Jewell, D.P., Hill, A.V. Nat. Med. (2000)
- Extensive study of DRB, DQA, and DQB gene polymorphism in 23 DR2-positive, insulin-dependent diabetes mellitus patients. Zeliszewski, D., Tiercy, J.M., Boitard, C., Gu, X.F., Loche, M., Krishnamoorthy, R., Simonney, N., Elion, J., Bach, J.F., Mach, B. Hum. Immunol. (1992)
- Suppression of human immunodeficiency virus expression in chronically infected monocytic cells by glutathione, glutathione ester, and N-acetylcysteine. Kalebic, T., Kinter, A., Poli, G., Anderson, M.E., Meister, A., Fauci, A.S. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Insulin-dependent diabetes mellitus during alpha-interferon therapy for chronic viral hepatitis. Fabris, P., Betterle, C., Greggio, N.A., Zanchetta, R., Bosi, E., Biasin, M.R., de Lalla, F. J. Hepatol. (1998)
- DQA1 and DQB1 heterodimers in insulin-dependent diabetes mellitus: a genetic-epidemiological study in Finland. DiMe Study Group. Tuomilehto-Wolf, E., Tuomilehto, J., Hitman, G.A. Ann. Med. (1992)
- Organic thiophosphate WR-151327 suppresses expression of HIV in chronically infected cells. Kalebic, T., Schein, P.S. AIDS Res. Hum. Retroviruses (1994)
- The human major histocompatibility complex class II HLA-DRB1 and HLA-DQA1 genes are separated by a CTCF-binding enhancer-blocking element. Majumder, P., Gomez, J.A., Boss, J.M. J. Biol. Chem. (2006)
- Description of an HLA-DQA1 RFLP allele [DQ alpha 4] defining DQw4/DRw8-bearing haplotypes. Martinez-Laso, J., Vicario, J.L., Regueiro, J.R., Corell, A., Paz-Artal, E., Arnaiz-Villena, A. Nucleic Acids Res. (1989)
- A new HLA-DQA1 RFLP allele [DQ alpha 3b] distinguishes between DQ alpha genes of DQw2-DR3 and DQw3-DR5 haplotypes. Martinez-Laso, J., Vicario, J.L., Corell, A., Morales, P., Regueiro, J.R., Arnaiz-Villena, A. Nucleic Acids Res. (1989)
- Increased rate of spontaneous mitotic recombination in T lymphocytes from a Bloom's syndrome patient using a flow-cytometric assay at HLA-A locus. Kusunoki, Y., Hayashi, T., Hirai, Y., Kushiro, J., Tatsumi, K., Kurihara, T., Zghal, M., Kamoun, M.R., Takebe, H., Jeffreys, A. Jpn. J. Cancer Res. (1994)
- T lymphocyte recognition of a celiac disease-associated cis- or trans-encoded HLA-DQ alpha/beta-heterodimer. Lundin, K.E., Sollid, L.M., Qvigstad, E., Markussen, G., Gjertsen, H.A., Ek, J., Thorsby, E. J. Immunol. (1990)
- The nonpolymorphic MHC class II isotype, HLA-DQA2, is expressed on the surface of B lymphoblastoid cells. Rudy, G.B., Lew, A.M. J. Immunol. (1997)
- Differential expression of insulin-dependent diabetes mellitus-associated HLA-DQA1 alleles in vivo. Maffei, A., Harris, P.E., Reed, E.F., Del Pozzo, G., Ciullo, M., Suciu-Foca, N., Guardiola, J. Eur. J. Immunol. (1997)
- Celiac disease and markers of celiac disease latency in patients with primary Sjögren's syndrome. Iltanen, S., Collin, P., Korpela, M., Holm, K., Partanen, J., Polvi, A., Mäki, M. Am. J. Gastroenterol. (1999)
- Celiac disease in children with autoimmune thyroid disease. Larizza, D., Calcaterra, V., De Giacomo, C., De Silvestri, A., Asti, M., Badulli, C., Autelli, M., Coslovich, E., Martinetti, M. J. Pediatr. (2001)
- Polymorphism of LDLR, GYPA, HBGG, D7S8, GC, HLA-DQA1, Ig-JH, D17S30, ApoB and D1S80 loci in northwestern Russians. Smolyanitsky, A.G., Smolyanitskaya, A.I., Popov, V.L., Zaslavsky, G.I., Khromov-Borisov, N.N. Forensic Sci. Int. (2003)
- Evidence of genetic heterogeneity in IBD: 1. The interleukin-1 receptor antagonist in the predisposition to suffer from ulcerative colitis. Bioque, G., Bouma, G., Crusius, J.B., Koutroubakis, I., Kostense, P.J., Meuwissen, S.G., Peña, A.S. European journal of gastroenterology & hepatology. (1996)
- Evolution of Mhc class II polymorphism: the rise and fall of class II gene function in primates. Bergström, T., Gyllensten, U. Immunol. Rev. (1995)
- Calcium activation of tissue transglutaminase in radioligand binding and enzyme-linked autoantibody immunoassays in childhood celiac disease. Agardh, D., Roth, B., Lernmark, A., Stenberg, P. Clin. Chim. Acta (2005)
- DEK binding to class II MHC Y-box sequences is gene- and allele-specific. Adams, B.S., Cha, H.C., Cleary, J., Haiying, T., Wang, H., Sitwala, K., Markovitz, D.M. Arthritis Res. Ther. (2003)
- Codon 17 polymorphism of the cytotoxic T lymphocyte antigen 4 gene in Hashimoto's thyroiditis and Addison's disease. Donner, H., Braun, J., Seidl, C., Rau, H., Finke, R., Ventz, M., Walfish, P.G., Usadel, K.H., Badenhoop, K. J. Clin. Endocrinol. Metab. (1997)
- Metalloelastase (MMP-12) is upregulated in the gut of pediatric patients with potential celiac disease and in type 1 diabetes. Bister, V., Kolho, K.L., Karikoski, R., Westerholm-Ormio, M., Savilahti, E., Saarialho-Kere, U. Scand. J. Gastroenterol. (2005)
- Evidence that an HLA-DQA1-DQB1 haplotype influences susceptibility to childhood common acute lymphoblastic leukaemia in boys provides further support for an infection-related aetiology. Taylor, G.M., Dearden, S., Payne, N., Ayres, M., Gokhale, D.A., Birch, J.M., Blair, V., Stevens, R.F., Will, A.M., Eden, O.B. Br. J. Cancer (1998)
- Association between HLA class II locus and the susceptibility to Artemisia pollen-induced allergic rhinitis in Chinese population. Wang, M., Xing, Z.M., Yu, D.L., Yan, Z., Yu, L.S. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. (2004)
- A genetic study of retinopathy in south Indian type 2 (non-insulin-dependent) diabetic patients. Hawrami, K., Mohan, R., Mohan, V., Hitman, G.A. Diabetologia (1991)
- MHC class I region plays a role in the development of diverse clinical forms of celiac disease in a Saharawi population. López-Vázquez, A., Fuentes, D., Rodrigo, L., González, S., Moreno, M., Fernández, E., Martínez-Borra, J., López-Larrea, C. Am. J. Gastroenterol. (2004)
- HLA class II allele and haplotype frequencies in Koreans based on 107 families. Song, E.Y., Park, M.H., Kang, S.J., Park, H.J., Kim, B.C., Tokunaga, K., Akaza, T., Juji, T. Tissue Antigens (2002)
- A SINE insertion provides information on the divergence of the HLA-DQA1 and HLA-DQA2 genes. Del Pozzo, G., Guardiola, J. Immunogenetics (1990)
- The HLA-DRB4 gene is present in half of the Spanish HLA-DQ2-negative celiac patients. Garrote, J.A., Arranz, E., Blanco-Quirós, A. Immunogenetics (2000)
- HLA alleles in the population of Cartagena (Colombia). Caraballo, L.R., Marrugo, J., Erlich, H., Pastorizo, M. Tissue Antigens (1992)
- DNA profiling in two Alaskan Native populations using HLA-DQA1, PM, and D1S80 loci. Walkinshaw, M., Strickland, L., Hamilton, H., Denning, K., Gayley, T. J. Forensic Sci. (1996)
- A method for estimating the intensity of overdominant selection from the distribution of allele frequencies. Slatkin, M., Muirhead, C.A. Genetics (2000)
- Associations between HLA class II alleles and type 1 diabetes mellitus in the Slovak population. Buc, M., Bucová, M., Javor, J., Krivosíkova, M., Stuchlíkova, M., Shawkatova, I., Michalková, D., Barák, L., Jancová, E., Petrek, M. Endocrine regulations. (2006)
- Association of amino acid sequences in the HLA-DQB1 first domain with antitopoisomerase I autoantibody response in scleroderma (progressive systemic sclerosis). Reveille, J.D., Durban, E., MacLeod-St Clair, M.J., Goldstein, R., Moreda, R., Altman, R.D., Arnett, F.C. J. Clin. Invest. (1992)