Chemical Compound Review:
Metholes 2-amino-3-(3,4- dihydroxyphenyl)-2-methyl...
Synonyms:
Mulfasin, DL-Methyldopa, CHEMBL718, SureCN196981, AG-F-93650, ...
- The effects of antihypertensive therapy on the quality of life. Croog, S.H., Levine, S., Testa, M.A., Brown, B., Bulpitt, C.J., Jenkins, C.D., Klerman, G.L., Williams, G.H. N. Engl. J. Med. (1986)
- Impaired reticuloendothelial function in patients treated with methyldopa. Kelton, J.G. N. Engl. J. Med. (1985)
- Alpha-methyldopa and carotid-sinus hypersensitivity. Morley, C.A., Perrins, E.J., Sutton, R. N. Engl. J. Med. (1981)
- Methyldopa inhibition of suppressor-lymphocyte function: a proposed cause of autoimmune hemolytic anemia. Kirtland, H.H., Mohler, D.N., Horwitz, D.A. N. Engl. J. Med. (1980)
- Methyldopa-induced thrombocytopenia in chronic lymphocytic leukemia. Shalev, O., Brezis, M. N. Engl. J. Med. (1977)
- alpha-Methyldopa and depression: a clinical study and review of the literature. DeMuth, G.W., Ackerman, S.H. The American journal of psychiatry. (1983)
- Biochemical and dynamic responses to single and repeated doses of methyldopa and propranolol during dynamic physical activity. Rosenthal, L., Affrime, M.B., Lowenthal, D.T., Falkner, B., Saris, S., Gould, A.B. Clin. Pharmacol. Ther. (1982)
- Effects of methyldopa on psychometric performance. Johnson, B., Hoch, K., Errichetti, A., Johnson, J. Journal of clinical pharmacology. (1990)
- Neurobehavioral teratogenic effects of clomipramine and alpha-methyldopa. De Boer, S., Mirmiran, M., Van Haaren, F., Louwerse, A., van de Poll, N.E. Neurotoxicology and teratology. (1989)
- Plasma concentration of alpha-methyldopa and sulphate conjugate after oral administration of methyldopa and intravenous administration of methyldopa and methyldopa hydrochloride ethyl ester. Saavedra, J.A., Reid, J.L., Jordan, W., Rawlins, M.D., Dollery, C.T. Eur. J. Clin. Pharmacol. (1975)
- Acute colitis with methyldopa. Graham, C.F., Gallagher, K., Jones, J.K. N. Engl. J. Med. (1981)
- Sinus node dysfunction caused by methyldopa and digoxin. Davis, J.C., Reiffel, J.A., Bigger, J.T. JAMA (1981)
- Comparison of oxprenolol and methyldopa in hypertension. A within-patient double-blind trial. Barritt, D.W., Marshall, A.J., Heaton, S. Lancet (1976)
- Short- and long-term efficacy of a calcium-antagonistic agent (nifedipine) combined with methyldopa in the treatment of severe hypertension. Guazzi, M.D., Fiorentini, C., Olivari, M.T., Bartorelli, A., Necchi, G., Polese, A. Circulation (1980)
- Methyldopa-induced systemic lupus erythematosus. Nordstrom, D.M., West, S.G., Rubin, R.L. Arthritis Rheum. (1989)
- The effect of single-dose methyldopa and diuretic on BP and left ventricular mass. Weinstein, M., Hilewitz, H., Rogel, S. Arch. Intern. Med. (1984)
- Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly trial. Amery, A., Birkenhäger, W., Brixko, P., Bulpitt, C., Clement, D., Deruyttere, M., De Schaepdryver, A., Dollery, C., Fagard, R., Forette, F. Lancet (1985)
- Pharmacological effects of alpha-methyldopa, alpha-methylnorepinephrine, and octopamine on rat arteriolar, arterial, and terminal vascular smooth. Altura, B.M. Circ. Res. (1975)
- Serologic profile of alphamethyldopa-induced hemolytic anemia: correlation between cell-bound IgM and hemolysis. Lalezari, P., Louie, J.E., Fadlallah, N. Blood (1982)
- Toxicity of methyldopa (Aldomet) to mouse neuroblastoma cells in vivo. Chelmicka-Schorr, E., Sportiello, M.G., Otten, G.R., Arnason, B.G. Cancer Res. (1983)
- Methyldopa. Mechanisms and treatment 25 years later. Frohlich, E.D. Arch. Intern. Med. (1980)
- Diet and uptake of aldomet by the brain: competition with natural large neutral amino acids. Markovitz, D.C., Fernstrom, J.D. Science (1977)
- Ultrastructural mapping of methyldopa and anti-D IgG erythrocyte antigen receptors. Masouredis, S.P., Sudora, E. J. Clin. Invest. (1975)
- Cardiovascular regulation by central adrenergic mechanisms and its alteration by hypotensive drugs. Haeusler, G. Circ. Res. (1975)
- Alpha-methyldopa disposition in mothers with hypertension and in their breast-fed infants. White, W.B., Andreoli, J.W., Cohn, R.D. Clin. Pharmacol. Ther. (1985)
- Rauwolfia use and breast cancer: a case-control study. Stanford, J.L., Martin, E.J., Brinton, L.A., Hoover, R.N. J. Natl. Cancer Inst. (1986)
- Effects of guanethidine and methyldopa on a standardized test for renin responsiveness. Lowder, S.C., Liddle, G.W. Ann. Intern. Med. (1975)
- Letter: Alpha methyldopa and forgetfulness. Fernandez, P.G. Ann. Intern. Med. (1976)
- Treatment of severe hypertension with labetalol compared with methyldopa and furosemide. Results of a long-term, double-blind, multicenter trial. Wallin, J.D., Wilson, D., Winer, N., Maronde, R.F., Michelson, E.L., Langford, H., Maloy, J., Poland, M. Am. J. Med. (1983)
- Antihypertensive treatment and plasma lipoprotein levels. The associations in data from a population study. MacMahon, S.W., Macdonald, G.J. Am. J. Med. (1986)
- Evidence for regulatory variants of the dopa decarboxylase and alpha-methyldopa hypersensitive loci in Drosophila. Marsh, J.L., Wright, T.R. Genetics (1986)
- Platelet phenol sulfotransferase and erythrocyte catechol-O-methyltransferase activities: correlation with methyldopa metabolism. Campbell, N.R., Dunnette, J.H., Mwaluko, G., Van Loon, J., Weinshilboum, R.M. Clin. Pharmacol. Ther. (1984)
- Inheritance of human platelet thermolabile phenol sulfotransferase (TL PST) activity. Price, R.A., Cox, N.J., Spielman, R.S., Van Loon, J.A., Maidak, B.L., Weinshilboum, R.M. Genet. Epidemiol. (1988)
- Effects of methyldopa on prolactin and growth hormone. Steiner, J., Cassar, J., Mashiter, K., Dawes, I., Fraser, T.R., Breckenridge, A. British medical journal. (1976)
- Left ventricular hypertrophy in elderly hypertensive patients: a report from the European Working Party on High Blood Pressure in the Elderly trial. Van Hoof, R. Am. J. Med. (1991)
- Antihypertensive efficacy of a single bedtime dose of methyldopa. Wright, J.M., McLeod, P.J., McCullough, W. Clin. Pharmacol. Ther. (1976)
- A double blind study to evaluate the effect of methyldopa on menopausal vasomotor flushes. Hammond, M.G., Hatley, L., Talbert, L.M. J. Clin. Endocrinol. Metab. (1984)
- Bulbospinal serotonin pressor pathways and hypotensive action of methyldopa in the rat. Chalmers, J.P., Minson, J.B., Choy, V. Hypertension (1984)
- Effects of labetalol and methyldopa on renal function. Cruz, F., O'Neill, W.M., Clifton, G., Wallin, J.D. Clin. Pharmacol. Ther. (1981)