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MeSH Review

Stomach Diseases

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Disease relevance of Stomach Diseases


High impact information on Stomach Diseases

  • The presence of three distinct serum markers of carcinoma, tumor-associated glycoprotein 72 (TAG-72; as measured by the CA 72-4 assay), CA 19-9, and carcinoembryonic antigen (CEA), was evaluated in 194 patients diagnosed with either malignant (n = 94) or benign (n = 100) gastric disease [5].
  • In 46 patients with different gastric diseases no correlation between the serum gastrin concentrations and the labelling indices was found [6].
  • The inhibition of gastric cell renewal by acetaldehyde may play a role in the pathogenesis of ethanol- and/or H. pylori-associated gastric diseases by inhibiting normal gastric mucosal protection and repair [7].
  • Sera with IgG antibody to H. pylori from five children with culture-proven H. pylori gastric disease markedly enhanced complement-dependent phagocytosis of H. pylori in an assay using flow cytometry to measure uptake of fluorescent-labeled bacteria by PMNL [8].
  • The aim of this study is to analyze the genetic and functional variability of cagA gene of clinical strains in relation to gastric diseases [9].

Chemical compound and disease context of Stomach Diseases

  • Nitrite concentration increased with severity of gastric disease but the results were not significant (normal, 82.9 vs. CAG, 223.4 ng/ml, P = 0.069) [10].
  • N-nitrosoproline excretion in the presence and absence of gastric disease [10].
  • It is concluded that 150 mg of roxatidine daily would be adequate to treat patients with gastric diseases [11].
  • All patients with gastric diseases who underwent combined T2-weighted single-shot echo train spin-echo and gadolinium-enhanced conventional and fat-suppressed spoiled gradient-echo imaging between October 1, 1996 and March 1, 1999, and who had histological or other imaging proof of disease, were included in this study [12].
  • RESULTS: Serum sucrose levels started to increase 15 min after loading, and peaked at 60 min in the gastric disease groups [3].

Biological context of Stomach Diseases


Anatomical context of Stomach Diseases


Gene context of Stomach Diseases


Analytical, diagnostic and therapeutic context of Stomach Diseases


  1. Helicobacter pylori cagA status and s and m alleles of vacA in isolates from individuals with a variety of H. pylori-associated gastric diseases. Evans, D.G., Queiroz, D.M., Mendes, E.N., Evans, D.J. J. Clin. Microbiol. (1998) [Pubmed]
  2. Cimetidine affords protection equal to antacids in prevention of stress ulceration following thermal injury. McElwee, H.P., Sirinek, K.R., Levine, B.A. Surgery (1979) [Pubmed]
  3. Significance of a novel sucrose permeability test using serum in the diagnosis of early gastric cancer. Shishido, T., Yamaguchi, T., Odaka, T., Seimiya, M., Saisho, H., Nomura, F. World J. Gastroenterol. (2005) [Pubmed]
  4. Incidence of atrophic gastritis with age in Japan and Canada. Kohli, Y., Kato, T., Suzuki, K., Tada, T., Fujiki, N. Jpn. J. Med. (1987) [Pubmed]
  5. CA 72-4 measurement of tumor-associated glycoprotein 72 (TAG-72) as a serum marker in the management of gastric carcinoma. Guadagni, F., Roselli, M., Amato, T., Cosimelli, M., Perri, P., Casale, V., Carlini, M., Santoro, E., Cavaliere, R., Greiner, J.W. Cancer Res. (1992) [Pubmed]
  6. Effect of gastrin on gastric mucosal cell proliferation in man. Hansen, O.H., Pedersen, T., Larsen, J.K., Rehfeld, J.F. Gut (1976) [Pubmed]
  7. Inhibition of gastric cell proliferation by acetaldehyde. Matysiak-Budnik, T., Kärkkäinen, P., Methuen, T., Roine, R.P., Salaspuro, M. J. Pathol. (1995) [Pubmed]
  8. Opsonic activity of specific human IgG against Helicobacter pylori. Tosi, M.F., Czinn, S.J. J. Infect. Dis. (1990) [Pubmed]
  9. Functional variability of cagA gene in Japanese isolates of Helicobacter pylori. Hirata, Y., Yanai, A., Shibata, W., Mitsuno, Y., Maeda, S., Ogura, K., Yoshida, H., Kawabe, T., Omata, M. Gene (2004) [Pubmed]
  10. N-nitrosoproline excretion in the presence and absence of gastric disease. Knight, T.M., Leach, S., Forman, D., Vindigni, C., Packer, P., Venitt, S., Minacci, C., Lorenzini, L., Tosi, P., Frosini, G. Eur. J. Cancer (1991) [Pubmed]
  11. Radiographic assessment of nocturnal gastric juice secretion after administration of roxatidine acetate hydrochloride. Tanioka, H., Terahara, A., Sasaki, Y. Clinical therapeutics. (1991) [Pubmed]
  12. Stomach diseases: MR evaluation using combined t2-weighted single-shot echo train spin-echo and gadolinium-enhanced spoiled gradient-echo sequences. Marcos, H.B., Semelka, R.C. Journal of magnetic resonance imaging : JMRI. (1999) [Pubmed]
  13. Association of cagA and vacA genotypes of Helicobacter pylori with gastric diseases in Estonia. Andreson, H., Lõivukene, K., Sillakivi, T., Maaroos, H.I., Ustav, M., Peetsalu, A., Mikelsaar, M. J. Clin. Microbiol. (2002) [Pubmed]
  14. Relationship between gastric disease and deletion of cag pathogenicity island genes of Helicobacter pylori in gastric juice. Kawamura, O., Murakami, M., Araki, O., Yamada, T., Tomizawa, S., Shimoyama, Y., Minashi, K., Maeda, M., Kusano, M., Mori, M. Dig. Dis. Sci. (2003) [Pubmed]
  15. Sex steroid metabolism in human gastric mucosa: 17 beta-hydroxysteroid dehydrogenase type 2 in normal, inflamed and neoplastic gastric tissues. Oduwole, O.O., Mäkinen, J.M., Isomaa, V.V., Karttunen, T.J., Vihko, P.T. Anticancer Res. (2003) [Pubmed]
  16. Efficacy of omeprazole for the prevention of exercise-induced gastritis in racing Alaskan sled dogs. Davis, M.S., Willard, M.D., Nelson, S.L., McCullough, S.M., Mandsager, R.E., Roberts, J., Payton, M.E. J. Vet. Intern. Med. (2003) [Pubmed]
  17. Effects of Hoelen on the efferent activity of the gastric vagus nerve in the rat. Okui, Y., Morita, M., Iizuka, A., Komatsu, Y., Okada, M., Maruno, M., Niijima, A. Jpn. J. Pharmacol. (1996) [Pubmed]
  18. Up-regulation of endothelin-1 in gastric mucosal inflammatory responses to Helicobacter pylori Lipopolysaccharide: effect of omeprazole and sucralfate. Slomiany, B.L., Piotrowski, J., Slomiany, A. J. Physiol. Pharmacol. (2000) [Pubmed]
  19. Molecular markers (PECAM-1, ICAM-3, HLA-DR) determine prognosis in primary non-Hodgkin's gastric lymphoma patients. Darom, A., Gomatos, I.P., Leandros, E., Chatzigianni, E., Panousopoulos, D., Konstadoulakis, M.M., Androulakis, G. World J. Gastroenterol. (2006) [Pubmed]
  20. Immunohistochemical detection of gastric mucin in normal and disease states. Taylor, K.L., Mall, A.S., Barnard, R.A., Ho, S.B., Cruse, J.P. Oncol. Res. (1998) [Pubmed]
  21. Topographic expression of MUC5AC and MUC6 in the gastric mucosa infected by Helicobacter pylori and in associated diseases. Marques, T., David, L., Reis, C., Nogueira, A. Pathol. Res. Pract. (2005) [Pubmed]
  22. Induction of chemokine and cytokine responses by Helicobacter pylori in human stomach explants. Lindholm, C., Quiding-Järbrink, M., Lönroth, H., Svennerholm, A.M. Scand. J. Gastroenterol. (2001) [Pubmed]
  23. ZNRD1 gene suppresses cell proliferation through cell cycle arrest in G1 phase. Hong, L., Han, Y., Shi, R., Shao, X., Sun, L., Zhang, Y., Huang, D., Chen, Z., Zhang, G., Liang, J., Hu, S., Fan, D. Cancer Biol. Ther. (2005) [Pubmed]
  24. Carcinoembryonic antigen in endoscopic brush specimens from benign and malignant gastric lesions. Lindgren, J., Sipponen, P., Seppälä, K., Tarpila, S., Nordling, S., Wahlström, T., Seppälä, M. Br. J. Cancer (1979) [Pubmed]
  25. Effect of food intake on urinary excretions of histamine, N tau-methylhistamine, imidazole acetic acid and its conjugate(s) in humans and mice. Imamura, I., Watanabe, T., Maeyama, K., Kubota, A., Okada, A., Wada, H. J. Biochem. (1984) [Pubmed]
  26. Comparison of roxatidine and famotidine on nocturnal gastric juice secretion. Tanioka, H., Kaga, K. J. Int. Med. Res. (1996) [Pubmed]
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