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MeSH Review

Life Tables

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Disease relevance of Life Tables


Psychiatry related information on Life Tables


High impact information on Life Tables

  • The life-table mortality rates in the two groups at one and six months were not significantly different (6.3 and 10.2 percent in the placebo group vs. 7.2 and 11.0 percent in the enalapril group, P = 0.26) [7].
  • The expression of Hpr epitopes was associated with earlier recurrence according to life-table analysis (P less than 0.0002) [8].
  • Reinfarction occurred in 27 patients in the placebo group (9.3 percent) and in 15 in the diltiazem group (5.2 percent)--a 51.2 percent reduction in cumulative life-table incidence (P = 0.0297; 90 percent confidence interval, 7 to 67 percent) [9].
  • Life-table analysis of two dosage schedules of chlorambucil at four years showed that 91 per cent of patients on low doses and 80 per cent of those on high doses were still in remission [10].
  • Survival rates of two groups of corticosteroid-treated patients with systemic lupus erythematosus (SLE) have been compared using life-table analysis [11].

Chemical compound and disease context of Life Tables


Biological context of Life Tables


Anatomical context of Life Tables

  • The risk of developing diabetes was estimated, using life-table methods, by years of follow-up and age, according to genetic factors (shared HLA-haplotypes, DR antigens, C4 allotypes) and islet cell antibody status [22].
  • For the subsamples (levels and areas of oral cavity) studied, the numerical distribution of TNM categories, life tables and life table comparisons were computed [23].

Associations of Life Tables with chemical compounds

  • A life-table method of analysis showed that the ulcer relapse rate was consistently and significantly lower on ranitidine that on cimetidine (8% v 21%, p = 0.0018 at 4 months; 14% v 34%, p less than 0.0001 at 8 months; and 23% v 37%, p = 0.004 at 12 months) [24].
  • These differences were statistically significant in favor of famotidine at weeks 6 (p less than or equal to 0.01) and 8 (p less than or equal to 0.05), as well as in a life-table analysis (p less than or equal to 0.05) [25].
  • Life-table analysis showed ongoing remission after 6 and 12 mo for Pentasa to be 63% (26 of 41) and 54% (22 of 41) and for Salazopyrin 72% (22 of 31) and 46% (14 of 31) [26].
  • Cholesterol-lowering therapy for smokers and non-smokers: a life-table analysis [27].
  • The probability of death after 84 months according to actuarial life-table analysis (Kaplan-Meier) was 30% for the amiodarone-treated patients and 45% for control patients [28].

Gene context of Life Tables

  • Life table analysis of the two groups indicated that the patients with the lower PCNA score survived significantly longer than those with the higher PCNA scores, P less than 0.04 [29].
  • Life-table estimates and Kaplan-Meier plots did not show any significant differences between patients who overexpressed an MDR protein compared with those who did not, nor was any difference noted when the different MDR + groups were compared with one another [30].
  • The association of staining for S100A4 with patient survival has been evaluated using life tables and analyzed using generalized Wilcoxon statistics [31].
  • Life-table analysis has effectively identified only two groups of patients that may be classified by progesterone receptor status alone [32].
  • The association of staining for OPN with survival times of the patients has been evaluated using life tables over 14-20 years of follow-up (mean 16 years) and analyzed using generalized Wilcoxon statistics [33].

Analytical, diagnostic and therapeutic context of Life Tables

  • The analyses of life-table methods revealed that adjunct hepatectomy, tumor size, bilirubin, albumin, globulin, and the 15-min retention rate of indocyanine green are statistically significant prognostic factors for hepatic arterial chemoembolization [34].
  • A life-table analysis of surgical outcomes was performed on the first eye of 155 patients who were enrolled in a pilot study of glaucoma filtering surgery with postoperative subconjunctival 5-fluorouracil (5-FU) injections [35].
  • Survival curves (life table method) comparing the two groups for up to nine years found higher hysterectomy rates for women aged 25-29 beginning at two years after tubal ligation and increasing with time [36].
  • In all, 62% of all patients, 72% of initial CSA responders, and 80% of initial CSA responders receiving 6MP/aza have avoided colectomy, with a life table analysis of "noncolectomy survival" of 58%, 70%, and 71%, respectively, at 5.5 yr [37].
  • Also, in vivo antitumor activity, as analyzed by a Kaplan-Meier life table with the log-rank test, revealed a significantly prolonged survival in the group treated with IL-2 plus cimetidine compared to the control groups [38].


  1. Sucralfate and ranitidine in the treatment of acute duodenal ulcer. Healing and relapse. Ulcer Study Group. Koelz, H.R., Halter, F. Am. J. Med. (1989) [Pubmed]
  2. Maintenance therapy for duodenal ulcer: a randomized controlled comparison of seven forms of treatment. Hui, W.M., Lam, S.K., Lok, A.S., Ng, M.M., Lai, C.L. Am. J. Med. (1992) [Pubmed]
  3. Familial factors determine the development of diabetic nephropathy in patients with IDDM. Quinn, M., Angelico, M.C., Warram, J.H., Krolewski, A.S. Diabetologia (1996) [Pubmed]
  4. Nocturnal therapy with famotidine for 1 year is effective in preventing relapse of gastric ulcer. Berlin, R.G., Root, J.K., Cook, T.J. Aliment. Pharmacol. Ther. (1991) [Pubmed]
  5. Oral trimethoprim/sulfamethoxazole for prevention of bacterial infection during the induction phase of cancer chemotherapy in children. Kovatch, A.L., Wald, E.R., Albo, V.C., Prin, W., Orlando, S.J., Wollman, M.R., Phebus, C.K., Shapiro, E.D. Pediatrics (1985) [Pubmed]
  6. The use of survival analysis techniques in evaluating the effect of long-term tacrine (Cognex) treatment on nursing home placement and mortality in patients with Alzheimer's disease. Smith, F., Talwalker, S., Gracon, S., Srirama, M. Journal of biopharmaceutical statistics. (1996) [Pubmed]
  7. Effects of the early administration of enalapril on mortality in patients with acute myocardial infarction. Results of the Cooperative New Scandinavian Enalapril Survival Study II (CONSENSUS II). Swedberg, K., Held, P., Kjekshus, J., Rasmussen, K., Rydén, L., Wedel, H. N. Engl. J. Med. (1992) [Pubmed]
  8. Haptoglobin-related protein (Hpr) epitopes in breast cancer as a predictor of recurrence of the disease. Kuhajda, F.P., Piantadosi, S., Pasternack, G.R. N. Engl. J. Med. (1989) [Pubmed]
  9. Diltiazem and reinfarction in patients with non-Q-wave myocardial infarction. Results of a double-blind, randomized, multicenter trial. Gibson, R.S., Boden, W.E., Theroux, P., Strauss, H.D., Pratt, C.M., Gheorghiade, M., Capone, R.J., Crawford, M.H., Schlant, R.C., Kleiger, R.E. N. Engl. J. Med. (1986) [Pubmed]
  10. Long-term evaluation of chlorambucil plus prednisone in the idiopathic nephrotic syndrome of childhood. Williams, S.A., Makker, S.P., Ingelfinger, J.R., Grupe, W.E. N. Engl. J. Med. (1980) [Pubmed]
  11. Corticosteroid treatment in systemic lupus erythematosus. Survival studies. Urman, J.D., Rothfield, N.F. JAMA (1977) [Pubmed]
  12. A trial-based cost-effectiveness analysis of letrozole followed by tamoxifen versus tamoxifen followed by letrozole for postmenopausal advanced breast cancer. Karnon, J., Johnston, S.R., Jones, T., Glendenning, A. Ann. Oncol. (2003) [Pubmed]
  13. Immunochemotherapy of lung cancer. Stewart, T.H., Hollinshead, A.C., Harris, J.E., Belanger, R., Crepeau, A., Hooper, G.D., Sachs, H.J., Klaassen, D.J., Hirte, W., Rapp, E., Crook, A.F., Orizaga, M., Sengar, D.P., Raman, S. Ann. N. Y. Acad. Sci. (1976) [Pubmed]
  14. Contribution of cadmium in cigarettes to lung cancer: an evaluation of risk assessment methodologies. Hertz-Picciotto, I., Hu, S.W. Arch. Environ. Health (1994) [Pubmed]
  15. Prevention of reinfarction subsequent to non-Q-wave infarction. Roberts, R., Gibson, R.S. J. Cardiovasc. Pharmacol. (1989) [Pubmed]
  16. Cost effectiveness of lowering cholesterol concentration with statins in patients with and without pre-existing coronary heart disease: life table method applied to health authority population. Pharoah, P.D., Hollingworth, W. BMJ (1996) [Pubmed]
  17. Age at diagnosis and transmission of invasive melanoma in 23 families with cutaneous malignant melanoma/dysplastic nevi. Goldstein, A.M., Fraser, M.C., Clark, W.H., Tucker, M.A. J. Natl. Cancer Inst. (1994) [Pubmed]
  18. Long-term follow-up of patients with lupus nephritis. A study based on the classification of the World Health Organization. Appel, G.B., Cohen, D.J., Pirani, C.L., Meltzer, J.I., Estes, D. Am. J. Med. (1987) [Pubmed]
  19. A life-table analysis of pregnancy yield in fixed low-dose menotropin therapy for patients in whom clomiphene citrate failed to induce ovulation. Goldfarb, A.F., Schlaff, S., Mansi, M.L. Fertil. Steril. (1982) [Pubmed]
  20. Methotrexate therapy in rheumatoid arthritis: a life table review of 587 patients treated in community practice. Buchbinder, R., Hall, S., Sambrook, P.N., Champion, G.D., Harkness, A., Lewis, D., Littlejohn, G.O., Miller, M.H., Ryan, P.F. J. Rheumatol. (1993) [Pubmed]
  21. Sublethal effects of tebufenpyrad on the eggs and immatures of two-spotted spider mite, Tetranychus urticae. Marcic, D. Exp. Appl. Acarol. (2005) [Pubmed]
  22. Life table analysis of the risk of type 1 (insulin-dependent) diabetes mellitus in siblings according to islet cell antibodies and HLA markers. An 8-year prospective study. Deschamps, I., Boitard, C., Hors, J., Busson, M., Marcelli-Barge, A., Mogenet, A., Robert, J.J. Diabetologia (1992) [Pubmed]
  23. Carcinoma of the oral cavity: on the prognostic significance of the primary tumour site (by levels and areas). Fries, R., Platz, H., Wagner, R., Strickler, A., Grabner, H., Kränzl, B., Krekeler, G., Kriens, O., Leijhanec, J., Mennert, H., Scharf, F., Schroll, K., Schulz, P., Vinek, G., Waldhart, E., Wepner, F., Zisser, G. Journal of maxillofacial surgery. (1979) [Pubmed]
  24. Ranitidine and cimetidine in prevention of duodenal ulcer relapse. A double-blind, randomised, multicentre, comparative trial. Gough, K.R., Korman, M.G., Bardhan, K.D., Lee, F.I., Crowe, J.P., Reed, P.I., Smith, R.N. Lancet (1984) [Pubmed]
  25. Suppression of nocturnal acid secretion with famotidine accelerates gastric ulcer healing. McCullough, A.J., Graham, D.Y., Knuff, T.E., Lanza, F.L., Levenson, H.L., Lyon, D.T., Munsell, W.P., Perozza, J., Roufail, W.M., Sinar, D.R. Gastroenterology (1989) [Pubmed]
  26. Double-blind comparison of slow-release 5-aminosalicylate and sulfasalazine in remission maintenance in ulcerative colitis. Mulder, C.J., Tytgat, G.N., Weterman, I.T., Dekker, W., Blok, P., Schrijver, M., van der Heide, H. Gastroenterology (1988) [Pubmed]
  27. Cholesterol-lowering therapy for smokers and non-smokers: a life-table analysis. Bonneux, L. Lancet (2000) [Pubmed]
  28. Long-term benefit of 1-year amiodarone treatment for persistent complex ventricular arrhythmias after myocardial infarction. Pfisterer, M.E., Kiowski, W., Brunner, H., Burckhardt, D., Burkart, F. Circulation (1993) [Pubmed]
  29. Relationship of proliferating cell nuclear antigen (PCNA) in prostatic carcinomas to various clinical parameters. Harper, M.E., Glynne-Jones, E., Goddard, L., Wilson, D.W., Matenhelia, S.S., Conn, I.G., Peeling, W.B., Griffiths, K. Prostate (1992) [Pubmed]
  30. The prognostic significance of P-glycoprotein, multidrug resistance-related protein 1 and lung resistance protein in pediatric acute lymphoblastic leukemia: a retrospective study of 295 newly diagnosed patients by the Children's Oncology Group. Olson, D.P., Taylor, B.J., La, M., Sather, H., Reaman, G.H., Ivy, S.P. Leuk. Lymphoma (2005) [Pubmed]
  31. Prognostic significance of the metastasis-inducing protein S100A4 (p9Ka) in human breast cancer. Rudland, P.S., Platt-Higgins, A., Renshaw, C., West, C.R., Winstanley, J.H., Robertson, L., Barraclough, R. Cancer Res. (2000) [Pubmed]
  32. Relative importance of estrogen and progesterone receptor assays as prognostic indicators in primary breast cancer: a short-term study. Brocklehurst, D., Wilde, C.E., Finbow, J.A., Brett, R., Champion, A.E., Dewhurst, D.G. Clin. Chem. (1989) [Pubmed]
  33. Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer. Rudland, P.S., Platt-Higgins, A., El-Tanani, M., De Silva Rudland, S., Barraclough, R., Winstanley, J.H., Howitt, R., West, C.R. Cancer Res. (2002) [Pubmed]
  34. Hepatocellular carcinoma: a multivariate analysis of prognostic features in patients treated with hepatic arterial embolization. Shijo, H., Okazaki, M., Higashihara, H., Koganemaru, F., Okumura, M. Am. J. Gastroenterol. (1992) [Pubmed]
  35. Glaucoma filtering surgery with 5-fluorouracil. Rockwood, E.J., Parrish, R.K., Heuer, D.K., Skuta, G.L., Hodapp, E., Palmberg, P.F., Gressel, M.G., Feuer, W. Ophthalmology (1987) [Pubmed]
  36. Long-term risk of hysterectomy after tubal sterilization. Cohen, M.M. Am. J. Epidemiol. (1987) [Pubmed]
  37. Intravenous cyclosporin in ulcerative colitis: a five-year experience. Cohen, R.D., Stein, R., Hanauer, S.B. Am. J. Gastroenterol. (1999) [Pubmed]
  38. Synergistic antitumor activity of interleukin-2 and cimetidine against syngeneic murine tumor. Nakajima, I., Chu, T.M. Cancer Immunol. Immunother. (1991) [Pubmed]
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