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Chemical Compound Review

AGN-PC-00YHTP     6-amino-3,3-dimethyl-7-oxo-4- thia-1...

Synonyms: SureCN178253, AG-K-83101, ANW-43708, CCG-34863, NSC-50071, ...
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Disease relevance of Penicin


Psychiatry related information on Penicin


High impact information on Penicin


Chemical compound and disease context of Penicin


Biological context of Penicin


Associations of Penicin with other chemical compounds


Gene context of Penicin


Analytical, diagnostic and therapeutic context of Penicin


  1. Antagonism of the antibacterial action of some penicillins by other penicillins and cephalosporins. Acar, J.F., Sabath, L.D., Ruch, P.A. J. Clin. Invest. (1975) [Pubmed]
  2. Cell surface changes in Pseudomonas aeruginosa PAO4069 in response to treatment with 6-aminopenicillanic acid. Godfrey, A.J., Bryan, L.E. Antimicrob. Agents Chemother. (1989) [Pubmed]
  3. Simple screening method for isolation of penicillin acylase-producing bacteria. Meevootisom, V., Somsuk, P., Prachaktam, R., Flegel, T.W. Appl. Environ. Microbiol. (1983) [Pubmed]
  4. N-(functionalized alkyl) derivatives of 6-aminopenicillanic acid: a new series of specific inhibitors of beta-lactamase from Enterobacter cloacae P99. Calverley, M.J., Begtrup, M. J. Antibiot. (1983) [Pubmed]
  5. Effect of nalidixic acid on the conversion of Staphylococcus aureus cells to L-forms in a liquid medium with 6-aminopenicillanic acid and lysozyme. Yabu, K. Microbiol. Immunol. (1986) [Pubmed]
  6. Kinetic investigation of penicillin G acylase from a mutant strain of Escherichia coli ATCC 11105 immobilized on oxirane-acrylic beads. Erarslan, A., Güray, A. Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986) (1991) [Pubmed]
  7. Steady-state kinetics of the binding of beta-lactams and penicilloates to the second binding site of the Enterobacter cloacae P99 beta-lactamase. Dryjanski, M., Pratt, R.F. Biochemistry (1995) [Pubmed]
  8. Penicillin-binding protein 2 is required for induction of the Citrobacter freundii class I chromosomal beta-lactamase in Escherichia coli. Oliva, B., Bennett, P.M., Chopra, I. Antimicrob. Agents Chemother. (1989) [Pubmed]
  9. Application of the fluorescamine reaction with 6-aminopenicillanic acid to estimation and detection of penicillin acylase activity. Baker, W.L. Antimicrob. Agents Chemother. (1983) [Pubmed]
  10. Molecular characterization of the acyl-coenzyme A:isopenicillin N acyltransferase gene (penDE) from Penicillium chrysogenum and Aspergillus nidulans and activity of recombinant enzyme in Escherichia coli. Tobin, M.B., Fleming, M.D., Skatrud, P.L., Miller, J.R. J. Bacteriol. (1990) [Pubmed]
  11. Acyl coenzyme A: 6-aminopenicillanic acid acyltransferase from Penicillium chrysogenum and Aspergillus nidulans. Whiteman, P.A., Abraham, E.P., Baldwin, J.E., Fleming, M.D., Schofield, C.J., Sutherland, J.D., Willis, A.C. FEBS Lett. (1990) [Pubmed]
  12. Penicillin acylase from the hybrid strains Escherichia coli 5K(pHM12): enzyme formation and hydrolysis of beta-lactam antibiotics with whole cells. Schömer, U., Segner, A., Wagner, F. Appl. Environ. Microbiol. (1984) [Pubmed]
  13. Design of an enzymatic hybrid system: a useful strategy for the biosynthesis of benzylpenicillin in vitro. Martínez-Blanco, H., Reglero, A., Martín-Villacorta, J., Luengo, J.M. FEMS Microbiol. Lett. (1990) [Pubmed]
  14. Cloning and characterization of the acyl-coenzyme A: 6-aminopenicillanic-acid-acyltransferase gene of Penicillium chrysogenum. Barredo, J.L., van Solingen, P., Díez, B., Alvarez, E., Cantoral, J.M., Kattevilder, A., Smaal, E.B., Groenen, M.A., Veenstra, A.E., Martín, J.F. Gene (1989) [Pubmed]
  15. Evidence for involvement of 2 histidine residues in the reaction of ampicillin acylase. Kim, D.J., Byun, S.M. Biochem. Biophys. Res. Commun. (1990) [Pubmed]
  16. Novel strategy for efficient screening and construction of host/vector systems to overproduce penicillin acylase in Escherichia coli. Chou, C.P., Yu, C.C., Lin, W.J., Kuo, B.Y., Wang, W.C. Biotechnol. Bioeng. (1999) [Pubmed]
  17. Characterization of the oral absorption of some beta-lactams: effect of the alpha-amino side chain group. Oh, D.M., Sinko, P.J., Amidon, G.L. Journal of pharmaceutical sciences. (1993) [Pubmed]
  18. A novel enzyme reactor using gluten membrane entrapping cell-associated enzyme. Lee, W.C., Guo, S.H. Biotechnol. Bioeng. (2001) [Pubmed]
  19. Equilibrium modeling of extractive enzymatic hydrolysis of penicillin G with concomitant 6-aminopenicillanic acid crystallization. Diender, M.B., Straathof, A.J., van der Does, T., Ras, C., Heijnen, J.J. Biotechnol. Bioeng. (2002) [Pubmed]
  20. Ionic strength and pH effects in the kinetically controlled synthesis of benzylpenicillin by nucleophilic deacylation of free and immobilized phenyl-acetyl-penicillin amidase with 6-aminopenicillanic acid. Kasche, V., Galunsky, B. Biochem. Biophys. Res. Commun. (1982) [Pubmed]
  21. Penicillin acylase-catalyzed ampicillin synthesis using a pH gradient: a new approach to optimization. Youshko, M.I., van Langen, L.M., de Vroom, E., van Rantwijk, F., Sheldon, R.A., Svedas, V.K. Biotechnol. Bioeng. (2002) [Pubmed]
  22. Titration of 6-aminopenicillanic acid with mercury (II) solution. Forsman, U., Karlberg, B. Anal. Chim. Acta (1976) [Pubmed]
  23. Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of beta-lactam antibiotics. Alkema, W.B., de Vries, E., Floris, R., Janssen, D.B. Eur. J. Biochem. (2003) [Pubmed]
  24. Outer membranes of gram-negative bacteria. XV. Transmembrane diffusion rates in lipoprotein-deficient mutants of Escherichia coli. Nikaido, H., Bavoil, P., Hirota, Y. J. Bacteriol. (1977) [Pubmed]
  25. Purification of penicillin-binding protein 2 of Escherichia coli. Curtis, S.J., Strominger, J.L. J. Bacteriol. (1981) [Pubmed]
  26. Reactions of pyrazolylborate-zinc-hydroxide complexes related to beta-lactamase activity. Gross, F., Vahrenkamp, H. Inorganic chemistry. (2005) [Pubmed]
  27. "In vitro" synthesis of different naturally-occurring, semisynthetic and synthetic penicillins using a new and effective enzymatic coupled system. Martínez-Blanco, H., Reglero, A., Luengo, J.M. J. Antibiot. (1991) [Pubmed]
  28. Antibacterial activity and chemical modifications of PS-5 at the C-3 side chain. Sakamoto, M., Yamamoto, K., Isshiki, K., Ishikura, T., Fukagawa, Y., Yoshioka, T. J. Antibiot. (1990) [Pubmed]
  29. Bacillus cereus 569/H penicillinase serine-44 acylation by diazotized 6-aminopenicillanic acid. Heckler, T.G., Day, R.A. Biochim. Biophys. Acta (1983) [Pubmed]
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