Gene Review:
ACY1 - aminoacylase 1
Homo sapiens
Synonyms:
ACY-1, ACY1D, Aminoacylase-1, HEL-S-5, N-acyl-L-amino-acid amidohydrolase
Pollegioni,
Lorenzi,
Rosini,
Marcone,
Molla,
Verga,
Cabri,
Pilone,
Asif,
Armstrong,
Voland,
Wieland,
Oellerich,
Shipkova,
Van Coster,
Gerlo,
Giardina,
Engelke,
Smet,
De Praeter,
Meersschaut,
De Meirleir,
Seneca,
Devreese,
Leroy,
Herga,
Perrier,
Wevers,
Lissens,
Sass,
Mohr,
Olbrich,
Engelke,
Horvath,
Fliegauf,
Loges,
Schweitzer-Krantz,
Moebus,
Weiler,
Kispert,
Superti-Furga,
Wevers,
Omran,
Krizková,
Zitnanová,
Mislovicová,
Masárová,
Sasinková,
Duracková,
Krajcovic,
Sawazaki,
Minezawa,
Natsch,
Gfeller,
Gygax,
Schmid,
Acuna,
- Human aminoacylase-1. Cloning, sequence, and expression analysis of a chromosome 3p21 gene inactivated in small cell lung cancer. Cook, R.M., Burke, B.J., Buchhagen, D.L., Minna, J.D., Miller, Y.E. J. Biol. Chem. (1993)
- Structural studies of lipooligosaccharides from Haemophilus ducreyi ITM 5535, ITM 3147, and a fresh clinical isolate, ACY1: evidence for intrastrain heterogeneity with the production of mutually exclusive sialylated or elongated glycoforms. Schweda, E.K., Jonasson, J.A., Jansson, P.E. J. Bacteriol. (1995)
- Isolation of two contigs of overlapping cosmids derived from human chromosomal band 3p21.1 and identification of 5 new 3p21.1 genes. Shridhar, V., Golembieski, W., Kamat, A., Smith, S.E., Phillips, N., Miller, O.J., Miller, Y., Smith, D.I. Somat. Cell Mol. Genet. (1994)
- Aminoacylase I deficiency: a novel inborn error of metabolism. Van Coster, R.N., Gerlo, E.A., Giardina, T.G., Engelke, U.F., Smet, J.E., De Praeter, C.M., Meersschaut, V.A., De Meirleir, L.J., Seneca, S.H., Devreese, B., Leroy, J.G., Herga, S., Perrier, J.P., Wevers, R.A., Lissens, W. Biochem. Biophys. Res. Commun. (2005)
- A specific bacterial aminoacylase cleaves odorant precursors secreted in the human axilla. Natsch, A., Gfeller, H., Gygax, P., Schmid, J., Acuna, G. J. Biol. Chem. (2003)
- Autocatalytic processing of the 20S proteasome. Seemuller, E., Lupas, A., Baumeister, W. Nature (1996)
- A protein catalytic framework with an N-terminal nucleophile is capable of self-activation. Brannigan, J.A., Dodson, G., Duggleby, H.J., Moody, P.C., Smith, J.L., Tomchick, D.R., Murzin, A.G. Nature (1995)
- Lack of expression of aminoacylase-1 in small cell lung cancer. Evidence for inactivation of genes encoded by chromosome 3p. Miller, Y.E., Minna, J.D., Gazdar, A.F. J. Clin. Invest. (1989)
- Chemical modification of serine at the active site of penicillin acylase from Kluyvera citrophila. Martín, J., Slade, A., Aitken, A., Arche, R., Virden, R. Biochem. J. (1991)
- Abnormal expression of sphingomyelin acylase in atopic dermatitis: an etiologic factor for ceramide deficiency? Murata, Y., Ogata, J., Higaki, Y., Kawashima, M., Yada, Y., Higuchi, K., Tsuchiya, T., Kawainami, S., Imokawa, G. J. Invest. Dermatol. (1996)
- Mutations of penicillin acylase residue B71 extend substrate specificity by decreasing steric constraints for substrate binding. Morillas, M., McVey, C.E., Brannigan, J.A., Ladurner, A.G., Forney, L.J., Virden, R. Biochem. J. (2003)
- Evolution of an acylase active on cephalosporin C. Pollegioni, L., Lorenzi, S., Rosini, E., Marcone, G.L., Molla, G., Verga, R., Cabri, W., Pilone, M.S. Protein Sci. (2005)
- Mapping of aminoacylase-1 and beta-galactosidase-A to homologous regions of human chromosome 3 and mouse chromosome 9 suggests location of additional genes. Naylor, S.L., Elliott, R.W., Brown, J.A., Shows, T.B. Am. J. Hum. Genet. (1982)
- Mutations in ACY1, the gene encoding aminoacylase 1, cause a novel inborn error of metabolism. Sass, J.O., Mohr, V., Olbrich, H., Engelke, U., Horvath, J., Fliegauf, M., Loges, N.T., Schweitzer-Krantz, S., Moebus, R., Weiler, P., Kispert, A., Superti-Furga, A., Wevers, R.A., Omran, H. Am. J. Hum. Genet. (2006)
- The human chromosome 3 gene cluster ACY1-CACNA1D-ZNF64-ATP2B2 is evolutionarily conserved in Ateles paniscus chamek (Platyrrhini, Primates). Seuánez, H.N., Lachtermacher, M., Canavez, F., Moreira, M.A. Cytogenet. Cell Genet. (1997)
- Human aminoacylase-1: cloning, regional assignment to distal chromosome 3p21.1, and identification of a cross-hybridizing sequence on chromosome 18. Miller, Y.E., Drabkin, H., Jones, C., Fisher, J.H. Genomics (1990)
- Proteins identified as targets of the acyl glucuronide metabolite of mycophenolic acid in kidney tissue from mycophenolate mofetil treated rats. Asif, A.R., Armstrong, V.W., Voland, A., Wieland, E., Oellerich, M., Shipkova, M. Biochimie (2007)
- Confirmation and further regional assignment of aminoacylase 1 (acy-1) on human chromosome 3 using a simplified detection method. Voss, R., Lerer, I., Povey, S., Solomon, E., Bobrow, M. Ann. Hum. Genet. (1980)
- The nucleotide sequence of human aminoacylase-1. Mitta, M., Kato, I., Tsunasawa, S. Biochim. Biophys. Acta (1993)
- The use of immobilized enzymes in the food industry: a review. Kilara, A., Shahani, K.M. CRC critical reviews in food science and nutrition. (1979)
- Genetic relationship between acylpeptide hydrolase and acylase, two hydrolytic enzymes with similar binding but different catalytic specificities. Jones, W.M., Scaloni, A., Bossa, F., Popowicz, A.M., Schneewind, O., Manning, J.M. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Assignment of the human housekeeping delta-aminolevulinate synthase gene (ALAS1) to chromosome band 3p21.1 by PCR analysis of somatic cell hybrids. Cotter, P.D., Drabkin, H.A., Varkony, T., Smith, D.I., Bishop, D.F. Cytogenet. Cell Genet. (1995)
- Polymorphism of the cobalt-activated acylase in human tissues. Ziomek, E., Szewczuk, A. Acta Biochim. Pol. (1978)
- Antioxidant and antimutagenic activity of mannan neoglycoconjugates: mannan-human serum albumin and mannan-penicillin G acylase. Krizková, L., Zitnanová, I., Mislovicová, D., Masárová, J., Sasinková, V., Duracková, Z., Krajcovic, J. Mutat. Res. (2006)
- The rat kidney acylase I, characterization and molecular cloning. Differences with other acylases I. Giardina, T., Perrier, J., Puigserver, A. Eur. J. Biochem. (2000)
- On the excited-state energy transfer between tryptophan residues in proteins: the case of penicillin acylase. Ercelen, S., Kazan, D., Erarslan, A., Demchenko, A.P. Biophys. Chem. (2001)
- The pig aminoacylase 1 (ACY1) and ribosomal protein L29 (RPL29)/heparin/heparan sulfate interacting protein (HIP) genes are located together at 13q21-->q22, corresponding to human 3p21.1. Sawazaki, T., Minezawa, M. Cytogenet. Cell Genet. (1999)
- Essential roles of zinc ligation and enzyme dimerization for catalysis in the aminoacylase-1/M20 family. Lindner, H.A., Lunin, V.V., Alary, A., Hecker, R., Cygler, M., Ménard, R. J. Biol. Chem. (2003)
- Roles of dimerization domain residues in binding and catalysis by aminoacylase-1. Lindner, H.A., Alary, A., Boju, L.I., Sulea, T., Ménard, R. Biochemistry (2005)