Disease relevance of praseodymium

• The polyP resonance increased when cells were treated with EDTA and broadened upon the addition of a shift reagent, praseodymium [1].
• After intravenous injection of praseodymium nitrate, female Wistar rats develop fatty livers [2].
• Intravenous injection of the light lanthanon praseodymium nitrate (10 mg/kg) into rats causes a marked liver toxicity which becomes manifest in hypoglycemia, inhibition of RNA and protein synthesis and accumulation of fat in liver tissue [3].
• Rats treated with praseodymium (7 mg/kg i.v.) developed a pronounced hypoglycemia [4].

High impact information on praseodymium

• On the other hand, energy transfer measurements using the lanthanide, praseodymium (Pr3+), as an acceptor indicate that IAEDANS is located 16-18 A from the binding site(s) of this calcium analog [5].
• Nucleic acid related compounds. 27. "Virtual coupling" of the anomeric proton of cyclic 2'-deoxynucleoside 3',5'-monophosphates. Reassessment of conformation using praseodymium shifts and assignment of H-2',2'' signals by biomimetic deuteration at C-2' [6].
• The body temperatures of eight anesthetized rats were measured in the liver after intravenous administration of 1 mmol/kg of the praseodymium complex under different heating conditions of the animal [7].
• The clastogenic property of two lanthanides, Praseodymium and Neodymium, was evaluated by scoring the frequencies of micronucleated cells in the interphase and chromosome/chromatid aberrations at ana-telophases in root tips of Vicia faba L [8].
• Alterations of rat serum lipoproteins and lecithin-cholesterol-acyltransferase activity in praseodymium-induced liver damage [9].

Chemical compound and disease context of praseodymium

• Silybin prevented praseodymium-induced hypoglycemia completely and the changes in the biochemical parameters of liver function partially but did not influence the decrease of liver GSH [4].

Biological context of praseodymium

• Here, we report that hybridization of surface-immobilized single-stranded oligonucleotide on praseodymium oxide (evaluated as a biosensor surface for the first time) with complimentary strands in solution provokes a significant shift of electrical impedance curve [10].
• Moreover, lanthanum itself as well as lanthanides other than cerium, e.g., gadolinium and didymium (praseodymium, neodymium), were successfully applied and can be recommended as capture agents for phosphatase cytochemistry [11].

Anatomical context of praseodymium

• The intravenously administered light lanthanon praseodymium selectively destroys the Golgi complex of rat exocrine pancreas [12].
• Effect of praseodymium on drug metabolism in rat liver smooth and rough endoplasmic reticulum [13].
• A small i.v. dose (3 mg/kg) of a light lanthanon, praseodymium, impairs the drug metabolizing capacity of both the smooth and rough fractions of rat liver endoplasmic reticulum [13].
• Erythrocyte alterations in praseodymium-induced lecithin:cholesterol acyltransferase (LCAT) deficiency in the rat: comparison with familial LCAT deficiency in man [14].

Associations of praseodymium with other chemical compounds

• After oral administration, silipide exhibited a significant and dose-related protective effect against the hepatotoxicity induced by CCl4, praseodymium, ethanol and galactosamine [15].
• In rats, i.v. administration of praseodymium, cerium and lanthanum (3 to 14 mg/kg) produced a dose-dependent increase in the serum activities of GOT, GPT and SDH [4].
• Four praseodymium complexes of aromatic carboxylates (benzoate, 4-tert-butylbenzoate, 2-benzoylbe-noate, and benzimidazole-5-carboxylate) have been synthesized and characterized, whose photophysical properties have been studied with ultraviolet spectra, phosphorescence spectra, and fluorescence spectra [16].
• The results of X-ray diffraction and energy-dispersive X-ray spectroscopy experiments indicate that these nanorods are pure praseodymium hydroxide with a hexagonal structure, which can be converted into praseodymium oxide (Pr6O11) nanorods of a face-centered cubic structure after calcination at 600 degrees C for 2 h in air [17].
• In this article, the surface properties of nanostructured ceria doped with praseodymium have been studied by X-ray photoelectron spectroscopy, secondary ion mass spectrometry, and Fourier transform infrared spectroscopy of adsorbed carbon monoxide [18].

Gene context of praseodymium

• The relative standard deviation is 1.2% for 7.0 x 10(-5) mol dm-3 of praseodymium [19].

Analytical, diagnostic and therapeutic context of praseodymium

• Praseodymium was investigated by Raman spectroscopy under pressure [20].
• Self-assemblies of octakis(octyloxy) phthalocyanine (PcOC8) and its sandwich lanthanide complex, substituted praseodymium bis(phthalocyanine) (Pr(PcOC8)(2)), with oligo(phenylene-ethynylene) (OPE) have been investigated by scanning tunneling microscopy (STM) on a highly oriented pyrolytic graphite (HOPG) surface [21].

References