Chemical Compound Review:
Bretylum (2-bromophenyl)methyl-ethyl- dimethyl-azanium
Synonyms:
Bretylium, CHEBI:3172, CHEMBL1199080, BSPBio_000904, CID2431, ...
- Pharmacokinetics of bretylium in renal insufficiency. Adir, J., Narang, P.K., Josselson, J., Sadler, J.H. N. Engl. J. Med. (1979)
- Bretylium tosylate: a newly available antiarrhythmic drug for ventricular arrhythmias. Heissenbuttel, R.H., Bigger, J.T. Ann. Intern. Med. (1979)
- Randomized, double-blind comparison of intravenous amiodarone and bretylium in the treatment of patients with recurrent, hemodynamically destabilizing ventricular tachycardia or fibrillation. The Intravenous Amiodarone Multicenter Investigators Group. Kowey, P.R., Levine, J.H., Herre, J.M., Pacifico, A., Lindsay, B.D., Plumb, V.J., Janosik, D.L., Kopelman, H.A., Scheinman, M.M. Circulation (1995)
- Polymorphous ventricular tachycardia associated with acute myocardial infarction. Wolfe, C.L., Nibley, C., Bhandari, A., Chatterjee, K., Scheinman, M. Circulation (1991)
- A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle. Kim, N., Azadzoi, K.M., Goldstein, I., Saenz de Tejada, I. J. Clin. Invest. (1991)
- Cerebroventricular calcitonin gene-related peptide inhibits rat duodenal bicarbonate secretion by release of norepinephrine and vasopressin. Lenz, H.J., Brown, M.R. J. Clin. Invest. (1990)
- Psychological stress-induced accelerated colonic transit in rats involves hypothalamic corticotropin-releasing factor. Mönnikes, H., Schmidt, B.G., Taché, Y. Gastroenterology (1993)
- Central action of recombinant interleukin-1 to inhibit acid secretion in rats. Saperas, E.S., Yang, H., Rivier, C., Taché, Y. Gastroenterology (1990)
- Peptidergic (enkephalin) innervation of the mammalian esophagus. Uddman, R., Alumets, J., Håkanson, R., Sundler, F., Walles, B. Gastroenterology (1980)
- Baroreflex control of the cutaneous active vasodilator system in humans. Kellogg, D.L., Johnson, J.M., Kosiba, W.A. Circ. Res. (1990)
- Bethanidine sulfate: efficacy in prevention of ventricular tachyarrhythmias during programmed stimulation. Report of a multicenter study of 56 patients. Teichman, S.L., Waspe, L.E., Matos, J.A., Kim, S.G., Fisher, J.D. J. Am. Coll. Cardiol. (1985)
- Changes in canine ventricular fibrillation threshold induced by verapamil, flecainide and bretylium. Quesada, A., Sanchis, J., Chorro, F.J., Burguera, M.A., Alberola, A., Such, L., Lopez-Merino, V. Eur. Heart J. (1993)
- Broad sensitivity of rodent arrhythmia models to class I, II, III, and IV antiarrhythmic agents. Brooks, R.R., Miller, K.E., Carpenter, J.F., Jones, S.M. Proc. Soc. Exp. Biol. Med. (1989)
- Central nervous system effects of corticotropin-releasing factor on gastrointestinal transit in the rat. Lenz, H.J., Burlage, M., Raedler, A., Greten, H. Gastroenterology (1988)
- Coronary vasoconstriction after percutaneous transluminal coronary angioplasty is attenuated by antiadrenergic agents. Gregorini, L., Fajadet, J., Robert, G., Cassagneau, B., Bernis, M., Marco, J. Circulation (1994)
- Hemodynamic and neural mechanisms of action of thyrotropin-releasing hormone in the rat. Sirén, A.L., Lake, C.R., Feuerstein, G. Circ. Res. (1988)
- The role of hypertension in the vascular disease and myocardial infarcts associated with murine systemic lupus erythematosus. Hang, L., Stephens-Larson, P., Henry, J.P., Dixon, F.J. Arthritis Rheum. (1983)
- A method for quantitating antifibrillatory effects of drugs after coronary reperfusion in dogs: improved outcome with bretylium. Wenger, T.L., Lederman, S., Starmer, C.F., Brown, T., Strauss, H.C. Circulation (1984)
- Membrane action and catecholamine release action of bretylium tosylate in normoxic and hypoxic canine Purkinje fibers. Nishimura, M., Watanabe, Y. J. Am. Coll. Cardiol. (1983)
- [3H]Xylamine accumulation by two sympathetically innervated tissues. Ransom, R.W., Waggaman, L.A., Cho, A.K. J. Neurochem. (1984)
- Nitrosyl factors mediate active neurogenic hindquarter vasodilation in the conscious rat. Davisson, R.L., Johnson, A.K., Lewis, S.J. Hypertension (1994)
- Evidence for nitric oxide-mediated sympathetic forearm vasodiolatation in humans. Dietz, N.M., Engelke, K.A., Samuel, T.T., Fix, R.T., Joyner, M.J. J. Physiol. (Lond.) (1997)
- The differential response of normal and ischaemic Purkinje fibres to clofilium, d-sotalol and bretylium. Gough, W.B., el-Sherif, N. Cardiovasc. Res. (1989)
- Effects of bretylium tosylate on inhomogeneity of refractoriness and ventricular fibrillation threshold in canine hearts with quinidine-induced long QT interval. Inoue, H., Toda, I., Nozaki, A., Matsuo, H., Sugimoto, T. Cardiovasc. Res. (1985)
- Antifibrillatory effects of high dose bretylium and a lidocaine-bretylium combination during cardiopulmonary resuscitation. Hanyok, J.J., Chow, M.S., Kluger, J., Fieldman, A. Crit. Care Med. (1988)
- Potentially significant drug interactions of class III antiarrhythmic drugs. Yamreudeewong, W., DeBisschop, M., Martin, L.G., Lower, D.L. Drug safety : an international journal of medical toxicology and drug experience. (2003)
- Bretylium differentiates between distinct signal transducing pathways in human lymphocytes. Pieri, C., Bacsó, Z., Recchioni, R., Moroni, F., Balázs, M., Gáspár, R., Damjanovich, S. Biochem. Biophys. Res. Commun. (1993)
- Pathways mediating CRF-induced inhibition of gastric acid secretion in rats. Drüge, G., Raedler, A., Greten, H., Lenz, H.J. Am. J. Physiol. (1989)
- Acute cold exposure induces vagally mediated Fos expression in gastric myenteric neurons in conscious rats. Yuan, P.Q., Taché, Y., Miampamba, M., Yang, H. Am. J. Physiol. Gastrointest. Liver Physiol. (2001)
- Drug therapy: bretylium. Koch-Weser, J. N. Engl. J. Med. (1979)
- Paradoxical ventricular tachycardia and fibrillation after intravenous bretylium therapy. Report of two cases. Anderson, J.L., Popat, K.D., Pitt, B. Arch. Intern. Med. (1981)
- Bretylium kinetics in renal insufficiency. Josselson, J., Narang, P.K., Adir, J., Yacobi, A., Sadler, J.H. Clin. Pharmacol. Ther. (1983)