Chemical Compound Review:
Methoxyamine O-methylhydroxylamine
Synonyms:
Methoxylamine, QMhHch@, CPD-7648, NCI-C60060, AG-L-18068, ...
- Inhibition of base excision repair potentiates iododeoxyuridine-induced cytotoxicity and radiosensitization. Taverna, P., Hwang, H.S., Schupp, J.E., Radivoyevitch, T., Session, N.N., Reddy, G., Zarling, D.A., Kinsella, T.J. Cancer Res. (2003)
- Characterization of two cold-sensitive mutants of the beta-galactosidase from Lactobacillus delbruckii subsp. bulgaricus. Adams, R.M., Yoast, S., Mainzer, S.E., Moon, K., Palombella, A.L., Estell, D.A., Power, S.D., Schmidt, B.F. J. Biol. Chem. (1994)
- A simple and efficient method for chemical mutagenesis of DNA. Kadonaga, J.T., Knowles, J.R. Nucleic Acids Res. (1985)
- Processing in vitro of an abasic site reacted with methoxyamine: a new assay for the detection of abasic sites formed in vivo. Rosa, S., Fortini, P., Karran, P., Bignami, M., Dogliotti, E. Nucleic Acids Res. (1991)
- Enhancement of manumycin A-induced apoptosis by methoxyamine in myeloid leukemia cells. She, M., Pan, I., Sun, L., Yeung, S.C. Leukemia (2005)
- Repair of N-methylpurines in specific DNA sequences in Chinese hamster ovary cells: absence of strand specificity in the dihydrofolate reductase gene. Scicchitano, D.A., Hanawalt, P.C. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Role of MutSalpha in the recognition of iododeoxyuridine in DNA. Berry, S.E., Loh, T., Yan, T., Kinsella, T.J. Cancer Res. (2003)
- DNA polymerase beta mediates protection of mammalian cells against ganciclovir-induced cytotoxicity and DNA breakage. Tomicic, M.T., Thust, R., Sobol, R.W., Kaina, B. Cancer Res. (2001)
- Mutagenic processing of ethylation damage in mammalian cells: the use of methoxyamine to study apurinic/apyrimidinic site-induced mutagenesis. Fortini, P., Calcagnile, A., Vrieling, H., van Zeeland, A.A., Bignami, M., Dogliotti, E. Cancer Res. (1993)
- The mechanism of the mutagenic action of hydroxylamine XIII. Reversion of phage MS2 amber mutants in the presence of hydroxylamines. Budowsky, E.I., Klebanova, L.M., Metlitskaya, A.Z. Mutat. Res. (1978)
- The effect of modification of cytosines in Escherichia coli 16-S rRNA on reconstitution and function of 30-S ribosomes. Wrede, A., Perzyński, S., Klita, S., Zagórska, L., Szafrański, P. Eur. J. Biochem. (1977)
- Secondary structure of the 5' end of bacteriophage MS2 RNA Methoxyamine and kethoxal modification. Iserentant, D., Fiers, W. Eur. J. Biochem. (1979)
- Characterization of inactivation of myxoviruses and paramyxoviruses by hydroxylamine, N-methylhydroxylamine and O-methylhydroxylamine. Newlin, G.E., Bussell, R.H. Arch. Virol. (1975)
- Repair of abasic sites by mammalian cell extracts. Frosina, G., Fortini, P., Rossi, O., Carrozzino, F., Abbondandolo, A., Dogliotti, E. Biochem. J. (1994)
- Methoxyamine modification of abasic sites protects CHO cells from the cytotoxic and mutagenic effects of oxygen alkylation. Fortini, P., Rosa, S., Zijno, A., Calcagnile, A., Bignami, M., Dogliotti, E. Carcinogenesis (1992)
- Hydroxylamine mutagenesis: observation of inverted Watson-Crick base-pairing between N4-methoxycytosine and adenine with the aid of natural-abundance high-resolution 15N NMR spectroscopy. Kierdaszuk, B., Stolarski, R., Shugar, D. Eur. J. Biochem. (1983)
- Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence. Yan, T., Seo, Y., Schupp, J.E., Zeng, X., Desai, A.B., Kinsella, T.J. Mol. Cancer Ther. (2006)
- DNA excision repair profiles of normal and leukemic human lymphocytes: functional analysis at the single-cell level. Buschfort, C., Muller, M.R., Seeber, S., Rajewsky, M.F., Thomale, J. Cancer Res. (1997)
- Microsomal metabolism of the 5-lipoxygenase inhibitor L-739,010: evidence for furan bioactivation. Zhang, K.E., Naue, J.A., Arison, B., Vyas, K.P. Chem. Res. Toxicol. (1996)
- Recognition of initiation codons in modified f2 RNA by Escherichia coli ribosomes. Szkopińska, A., Zagórski, W., Zagórska, L., Szafrański, P. Eur. J. Biochem. (1975)
- Modulation of base excision repair alters cellular sensitivity to UVA1 but not to UVB1. Kim, K.J., Chakrabarty, I., Li, G.Z., Grösch, S., Kaina, B., Rünger, T.M. Photochem. Photobiol. (2002)
- Protection against methylation-induced cytotoxicity by DNA polymerase beta-dependent long patch base excision repair. Horton, J.K., Prasad, R., Hou, E., Wilson, S.H. J. Biol. Chem. (2000)
- Mechanism of hydroxylamine mutagenesis: tautomeric shifts and proton exchange between the promutagen N6-methoxyadenosine and cytidine. Stolarski, R., Kierdaszuk, B., Hagberg, C.E., Shugar, D. Biochemistry (1987)
- Characterization of the lysyl adducts formed from prostaglandin H2 via the levuglandin pathway. Boutaud, O., Brame, C.J., Salomon, R.G., Roberts, L.J., Oates, J.A. Biochemistry (1999)
- Cluster of point mutations predetermined by a quasipalindromic nucleotide sequence in plasmid pBR322 DNA. Salganik, R.I., Dianov, G.L., Medvedev, O.A. FEBS Lett. (1990)
- Two expressed human genes sustain slightly more DNA damage after alkylating agent treatment than an inactive gene. Bartlett, J.D., Scicchitano, D.A., Robison, S.H. Mutat. Res. (1991)
- Involvement of two endonuclease III homologs in the base excision repair pathway for the processing of DNA alkylation damage in Saccharomyces cerevisiae. Hanna, M., Chow, B.L., Morey, N.J., Jinks-Robertson, S., Doetsch, P.W., Xiao, W. DNA Repair (Amst.) (2004)
- Mutagenesis of ribosomal protein S8 from Escherichia coli: defects in regulation of the spc operon. Wower, I., Kowaleski, M.P., Sears, L.E., Zimmermann, R.A. J. Bacteriol. (1992)
- The emerging role of DNA repair proteins as predictive, prognostic and therapeutic targets in cancer. Madhusudan, S., Middleton, M.R. Cancer Treat. Rev. (2005)
- A stronger DNA damage-induced G2 checkpoint due to over-activated CHK1 in the absence of PARP-1. Lu, H.R., Wang, X., Wang, Y. Cell Cycle (2006)
- Interactions of methoxyamine with pyridoxal-5'-phosphate-Schiff's base at the active site of sheep liver serine hydroxymethyltransferase. Acharya, J.K., Prakash, V., Rao, A.G., Savithri, H.S., Rao, N.A. Indian J. Biochem. Biophys. (1991)
- Trace determination of hydroxyl radical in biological systems. Li, B., Gutierrez, P.L., Blough, N.V. Anal. Chem. (1997)
- Base-pairing properties of N4-methoxydeoxycytidine 5'-triphosphate during DNA synthesis on natural templates, catalyzed by DNA polymerase I of Escherichia coli. Reeves, S.T., Beattie, K.L. Biochemistry (1985)
- Epinephrine, norepinephrine, and dopamine during a 4-day head-down bed rest. Pequignot, J.M., Guell, A., Gauquelin, G., Jarsaillon, E., Annat, G., Bes, A., Peyrin, L., Gharib, C. J. Appl. Physiol. (1985)
- The biosynthesis of 1a, 1b-dihomo-PGF2 and 1a,1b-dihomo-PGF2 alpha from 7, 10, 13, 16-docosatetraenoic acid by an acetone-pentane powder of sheep vesicular gland microsomes. Tobias, L.D., Vane, F.M., Paulsrud, J.R. Prostaglandins (1975)