Disease relevance of potassium nitrate

• We have developed a method for quantitating corneal neovascularization, induced in anesthetized rats by silver nitrate/potassium nitrate cauterization, using a LeMont OASYS video input image analyzer [1].
• The therapeutic response (decline in dentinal hypersensitivity) to potassium nitrate was evident within 1 week and increased continuously for the length of the study period [2].
• Nitrate poisoning was induced in a cow by giving it 200 g potassium nitrate through a rumen fistula for three to four days in succession [3].
• Sodium nitrite and potassium nitrate in control of nonproteolytic Clostridium botulinum outgrowth and toxigenesis in vacuum-packed cold-smoked rainbow trout [4].
• Potassium nitrate: an effective treatment for pulpitis [5].

High impact information on potassium nitrate

• METHODS: Ten healthy fasting volunteers were studied twice, after oral administration of 2 mmol of potassium nitrate or potassium chloride [6].
• Adult male Sprague-Dawley rats were anesthetized with halothane gas, and the centers of their right corneas treated with a silver nitrate applicator stick (75% silver nitrate, 25% potassium nitrate) to produce a discrete lesion 1 mm in diameter [7].
• These results were confirmed by swelling experiments of non-respiring mitochondria in potassium nitrate medium [8].
• Both ntrC mutants were unable to utilize potassium nitrate as a sole nitrogen source [9].
• Salt stress reduced total plant biomass by 27-38%, whereas potassium nitrate supplementation partially counteracted this effect by increasing dry matter and new leaf area [10].

Chemical compound and disease context of potassium nitrate

• Clinical relevance: Five per cent potassium nitrate, 2% sodium fluoride bio-adhesive gels and one-step bonding agent Prompt L-Pop were effective in reducing moderate dentine hypersensitivity [11].
• Dentine hypersensitivity and the placebo response. A comparison of the effect of strontium acetate, potassium nitrate and fluoride toothpastes [12].
• The effect on dentinal hypersensitivity from the use of a dentifrice containing 5.0% potassium nitrate, 1500 ppm sodium monofluorophosphate in a precipitated calcium carbonate (PCC) base over an eight-week period was compared to a placebo dentifrice without potassium nitrate [13].
• The two groups were randomly assigned to use either the Sensitive/Tartar Control dentifrice or the commercially available hypersensitivity control dentifrice with potassium nitrate [14].
• Results showed that 10% strontium chloride solution, 2% sodium fluoride solution, and 40% formalin solution significantly reduced dentin hypersensitivity, whereas a 5% solution of potassium nitrate did not [15].

Biological context of potassium nitrate

• The effect of exercise associated with acute poisoning with potassium nitrate and sodium nitrite on the processes of intestinal absorption of D-xylose in rats [16].
• In the mouse isolated phrenic nerve-hemidiaphragm preparation, the pharmacological profile of the first component was similar to that for authentic potassium nitrate which augments in low concentrations, and in higher concentrations augments, and then blocks both directly evoked muscle contraction the neuromuscular transmission [17].
• Ethanol, E.D.T.A., potassium nitrate, temperature of 25 degrees C and aerobiosis are considered favourable factors to conversion of the mould phase [18].
• The kinetics and mechanism of the reduction of oxidized cytochrome c by ascorbate has been investigated in potassium nitrate, potassium 4-morpholineethanesulfonate (KMes), potassium sulfate and potassium ascorbate media [19].
• Phenol oxidase and potassium nitrate assimilation were positive and gelatinase activity and casein hydrolysis were negative for all isolates [20].

Anatomical context of potassium nitrate

• Efficacy of a potassium nitrate mouthwash in alleviating cervical dentine sensitivity (CDS) [21].
• The third strategy is to desensitize the nerve tissue within the tubules using potassium nitrate [22].

Associations of potassium nitrate with other chemical compounds

• To demonstrate the utility of the method, we measured over the course of 18 days, the total area of neovascularization in rabbit corneas cauterized with silver/potassium nitrate, and treated topically with either normal saline (control) or 1% prednisolone acetate (100 microliters four times daily for 10 days) [23].
• The cyano content in the sample is distilled as hydrocyanic acid, trapped in 0.1 M potassium nitrate at pH 12-13, and determined by means of the cyanide ion-selective electrode [24].
• A total of 405 lactic acid bacteria (LAB) isolated from spoiled, vacuum-packaged, salted, sodium nitrite- or potassium nitrate-treated, cold-smoked rainbow trout stored at 4 degrees C or 8 degrees C were characterised and identified using a molecular method [25].
• Nitrates added in the form of a 1 M potassium nitrate solution were observed to completely disappear in conjunction with significant recovery of pH and alkalinity (i.e. biological denitrification) [26].
• The purpose of this study was to evaluate the effectiveness of a patient-applied 10% potassium nitrate glycerine-based gel in decreasing dentinal sensitivity on cold on teeth with exposed dentin apical to the cemento-enamel junction, 12 patients, each having 3 hypersensitive teeth, were tested [27].

Gene context of potassium nitrate

• Using potassium nitrate as N source in mixtures of 0.04 g N/g substrate (0.04% wt./vol.) at pH 4.5, it was found that incubation periods of 3, 4, and 5 days were optimal for protein production on cellulose and holocellulose fractions, and whole straw, respectively [28].

Analytical, diagnostic and therapeutic context of potassium nitrate

• The subjects were divided into 2 groups, with 18 being given a 5% potassium nitrate dentifrice (treated group) and the other 18 a vehicle paste (control group) [29].
• The effectiveness of a 5% potassium nitrate dentifrice as a daily home treatment for dentinal hypersensitivity was evaluated in a double-blind study in 36 Japanese subjects who complained of cold and/or tactile hypersensitivity [29].
• Four studies were included in the meta-analysis which showed statistically significant effect of potassium nitrate toothpaste on air blast and tactile sensitivity, e.g. the meta analysis of air blast sensitivity showed a standardized mean difference in sensitivity score of -1.51 (95% CI: -2.09 to -0.94) in favour of treatment [30].
• The results of this serological test were very satisfactory with respect to accuracy and rapidity, particularly when performed in combination with concomitant physiological tests only for assimilation of inositol and potassium nitrate [31].
• In this study, a 4% potassium nitrate-zinc oxide eugenol temporary cement was used to secure provisional crowns over recently prepared teeth and it significantly reduced the incidence and severity of pain after tooth preparation and impression taking [32].

References