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Chemical Compound Review

ACENAPHTHENE     acenaphthene

Synonyms: A104_ALDRICH, NSC-7657, CCRIS 5951, AG-J-22834, CHEMBL1797271, ...
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Disease relevance of acenaphthene


High impact information on acenaphthene


Chemical compound and disease context of acenaphthene


Biological context of acenaphthene


Anatomical context of acenaphthene


Associations of acenaphthene with other chemical compounds


Gene context of acenaphthene

  • Further analysis revealed that the low efficacy of acenaphthylene as inducer of CYP1A1 protein and EROD activity is due to its marked cytotoxicity while no clear-cut explanation was found for the differences in efficacy between benzo[k]fluoranthene and benzo[a]pyrene [21].
  • A comparison with other C(12)H(6) and C(12)H(8) isomers indicates that 2 is approximately 25 kcal/mol less stable than 1,5,9-tridehydro[12]annulene and 4 is approximately 100 kcal/mol higher in energy than acenaphthylene, both of which are synthetically accessible [22].
  • The RTP signal of fluorene and acenaphthene included on the beta-CD-modified paper was increased more than 10 times compared with non-modified filter paper, indicating the formation of the inclusion complex [19].
  • With the exception of acenaphthene, average concentrations of all measured PAH at BROS exceed those at EROS, with a paired t-test revealing these roadside increments to be significant (p < 0.05) for 9 out of the 16 target PAH, demonstrating the importance of traffic emissions of PAH [23].

Analytical, diagnostic and therapeutic context of acenaphthene


  1. Bacterial oxidation of the polycyclic aromatic hydrocarbons acenaphthene and acenaphthylene. Schocken, M.J., Gibson, D.T. Appl. Environ. Microbiol. (1984) [Pubmed]
  2. Novel Intermediates of Acenaphthylene Degradation by Rhizobium sp. Strain CU-A1: Evidence for Naphthalene-1,8-Dicarboxylic Acid Metabolism. Poonthrigpun, S., Pattaragulwanit, K., Paengthai, S., Kriangkripipat, T., Juntongjin, K., Thaniyavarn, S., Petsom, A., Pinphanichakarn, P. Appl. Environ. Microbiol. (2006) [Pubmed]
  3. Use of 13C nuclear magnetic resonance to assess fossil fuel biodegradation: fate of [1-13C]acenaphthene in creosote polycyclic aromatic compound mixtures degraded by bacteria. Selifonov, S.A., Chapman, P.J., Akkerman, S.B., Gurst, J.E., Bortiatynski, J.M., Nanny, M.A., Hatcher, P.G. Appl. Environ. Microbiol. (1998) [Pubmed]
  4. Functional and transcriptional analyses of the initial oxygenase genes for acenaphthene degradation from Sphingomonas sp. strain A4. Kouzuma, A., Pinyakong, O., Nojiri, H., Omori, T., Yamane, H., Habe, H. Microbiology (Reading, Engl.) (2006) [Pubmed]
  5. Acute and chronic life cycle toxicity of acenaphthene and 2,4,6-trichlorophenol to the midge Paratanytarsus parthenogeneticus (Diptera: Chironomidae). Meier, P.G., Choi, K., Sweet, L.I. Aquat. Toxicol. (2000) [Pubmed]
  6. Biomarker alterations produced in rat lung by intratracheal instillations of air particulate extracts and chemoprevention with oral N-acetylcysteine. Izzotti, A., Camoirano, A., D'Agostini, F., Sciacca, S., De Naro Papa, F., Cesarone, C.F., De Flora, S. Cancer Res. (1996) [Pubmed]
  7. The aromaticity of pyracylene: an experimental and computational study of the energetics of the hydrogenation of acenaphthylene and pyracylene. Diogo, H.P., Kiyobayashi, T., Minas da Piedade, M.E., Burlak, N., Rogers, D.W., McMasters, D., Persy, G., Wirz, J., Liebman, J.F. J. Am. Chem. Soc. (2002) [Pubmed]
  8. Piperonyl butoxide and acenaphthylene induce cytochrome P450 1A2 and 1B1 mRNA in aromatic hydrocarbon-responsive receptor knock-out mouse liver. Ryu, D.Y., Levi, P.E., Fernandez-Salguero, P., Gonzalez, F.J., Hodgson, E. Mol. Pharmacol. (1996) [Pubmed]
  9. The carbon skeleton of the belt region of fullerene C84 (D2). Neudorff, W.D., Lentz, D., Anibarro, M., Schlüter, A.D. Chemistry (Weinheim an der Bergstrasse, Germany) (2003) [Pubmed]
  10. Aryl hydrocarbon (Ah) receptor-independent induction of Cyp1a2 gene expression by acenaphthylene and related compounds in B6C3F1 mice. Chaloupka, K., Santostefano, M., Goldfarb, I.S., Liu, G., Myers, M.J., Tsyrolv, I.B., Gelboin, H.V., Krishnan, V., Safe, S. Carcinogenesis (1994) [Pubmed]
  11. Cloning and analysis of the genes for polycyclic aromatic hydrocarbon degradation. Zylstra, G.J., Wang, X.P., Kim, E., Didolkar, V.A. Ann. N. Y. Acad. Sci. (1994) [Pubmed]
  12. cis- and trans-1,2-diphenylaziridines: induction of xenobiotic-metabolizing enzymes in rat liver and mutagenicity in Salmonella typhimurium. Glatt, H.R., Robertson, L.W., Arand, M., Rauch, P., Schramm, H., Setiabudi, F., Pöchlauer, P., Müller, E.P., Oesch, F. Arch. Toxicol. (1986) [Pubmed]
  13. Reactions of hydroxyl radicals and ozone with acenaphthene and acenaphthylene. Reisen, F., Arey, J. Environ. Sci. Technol. (2002) [Pubmed]
  14. Polycyclic aromatic hydrocarbons-induced vasorelaxation through activation of nitric oxide synthase in endothelium of rat aorta. Kang, J.J., Cheng, Y.W. Toxicol. Lett. (1997) [Pubmed]
  15. Cloning, expression, and characterization of a self-sufficient cytochrome P450 monooxygenase from Rhodococcus ruber DSM 44319. Liu, L., Schmid, R.D., Urlacher, V.B. Appl. Microbiol. Biotechnol. (2006) [Pubmed]
  16. Mediating role of metabolic activation in in vitro cytotoxicity assays. Babich, H., Martin-Alguacil, N., Borenfreund, E. Molecular toxicology. (1987) [Pubmed]
  17. Radical-molecule reactions for aromatic growth: a case study for cyclopentadienyl and acenaphthylene. Wang, D., Violi, A. J. Org. Chem. (2006) [Pubmed]
  18. Simultaneous determination of ethylbenzene, indan, indene and acenaphthene in air by capillary gas chromatography. Bieniek, G. Journal of chromatography. A. (2000) [Pubmed]
  19. Application of functional group modified substrate in room-temperature phosphorescence, I--beta-cyclodextrin modified paper substrate for enrichment and determination of fluorene and acenaphthene. Zhu, R., Wang, P., Wang, X. Luminescence : the journal of biological and chemical luminescence. (2005) [Pubmed]
  20. Polynuclear aromatic hydrocarbons in crops from long-term field experiments amended with sewage sludge. Wild, S.R., Berrow, M.L., McGrath, S.P., Jones, K.C. Environ. Pollut. (1992) [Pubmed]
  21. Potency of various polycyclic aromatic hydrocarbons as inducers of CYP1A1 in rat hepatocyte cultures. Till, M., Riebniger, D., Schmitz, H.J., Schrenk, D. Chem. Biol. Interact. (1999) [Pubmed]
  22. Dicyclobuta[de,ij]naphthalene and dicyclopenta[cd,gh]pentalene: a theoretical study. Macaluso, M., Parish, C.A., Hoffmann, R., Scott, L.T. J. Org. Chem. (2004) [Pubmed]
  23. Concentrations, sources and temporal trends in atmospheric polycyclic aromatic hydrocarbons in a major conurbation. Harrad, S., Laurie, L. Journal of environmental monitoring : JEM. (2005) [Pubmed]
  24. Crystallographic observation of an olefin photodimerization reaction that takes place via thermal molecular tumbling within a self-assembled host. Takaoka, K., Kawano, M., Ozeki, T., Fujita, M. Chem. Commun. (Camb.) (2006) [Pubmed]
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