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Gene Review

aroA  -  3-phosphoshikimate 1-carboxyvinyltransferase

Escherichia coli CFT073

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Disease relevance of aroA


High impact information on aroA


Chemical compound and disease context of aroA


Biological context of aroA


Anatomical context of aroA


Associations of aroA with chemical compounds


Analytical, diagnostic and therapeutic context of aroA


  1. An Escherichia coli hemolysin transport system-based vector for the export of polypeptides: export of Shiga-like toxin IIeB subunit by Salmonella typhimurium aroA. Tzschaschel, B.D., Guzmán, C.A., Timmis, K.N., de Lorenzo, V. Nat. Biotechnol. (1996) [Pubmed]
  2. Molecular analysis of the aroA gene of Pasteurella multocida and vaccine potential of a constructed aroA mutant. Homchampa, P., Strugnell, R.A., Adler, B. Mol. Microbiol. (1992) [Pubmed]
  3. Antibody responses in the lungs of mice following oral immunization with Salmonella typhimurium aroA and invasive Escherichia coli strains expressing the filamentous hemagglutinin of Bordetella pertussis. Guzmán, C.A., Brownlie, R.M., Kadurugamuwa, J., Walker, M.J., Timmis, K.N. Infect. Immun. (1991) [Pubmed]
  4. Cloning and nucleotide sequence of the aroA gene of Bordetella pertussis. Maskell, D.J., Morrissey, P., Dougan, G. J. Bacteriol. (1988) [Pubmed]
  5. A single amino acid substitution in the enzyme 5-enolpyruvylshikimate-3-phosphate synthase confers resistance to the herbicide glyphosate. Stalker, D.M., Hiatt, W.R., Comai, L. J. Biol. Chem. (1985) [Pubmed]
  6. The aroA gene of Campylobacter jejuni. Wösten, M.M., Dubbink, H.J., van der Zeijst, B.A. Gene (1996) [Pubmed]
  7. Construction and characterization in vivo of Bordetella pertussis aroA mutants. Roberts, M., Maskell, D., Novotny, P., Dougan, G. Infect. Immun. (1990) [Pubmed]
  8. Wild-type intracellular bacteria deliver DNA into mammalian cells. Grillot-Courvalin, C., Goussard, S., Courvalin, P. Cell. Microbiol. (2002) [Pubmed]
  9. An aromatic-dependent mutant of the fish pathogen Aeromonas salmonicida is attenuated in fish and is effective as a live vaccine against the salmonid disease furunculosis. Vaughan, L.M., Smith, P.R., Foster, T.J. Infect. Immun. (1993) [Pubmed]
  10. Construction of stable LamB-Shiga toxin B subunit hybrids: analysis of expression in Salmonella typhimurium aroA strains and stimulation of B subunit-specific mucosal and serum antibody responses. Su, G.F., Brahmbhatt, H.N., Wehland, J., Rohde, M., Timmis, K.N. Infect. Immun. (1992) [Pubmed]
  11. Yersinia enterocolitica aroA mutants as carriers of the B subunit of the Escherichia coli heat-labile enterotoxin to the murine immune system. O'Gaora, P., Roberts, M., Bowe, F., Hormaeche, C., Demarco de Hormaeche, R., Cafferkey, M., Tite, J., Dougan, G. Microb. Pathog. (1990) [Pubmed]
  12. Over-production of 5-enolpyruvylshikimate-3-phosphate synthase in Escherichia coli: use of the T7 promoter. Shuttleworth, W.A., Hough, C.D., Bertrand, K.P., Evans, J.N. Protein Eng. (1992) [Pubmed]
  13. Molecular gene cloning and nucleotide sequencing and construction of an aroA mutant of Pasteurella haemolytica serotype A1. Tatum, F.M., Briggs, R.E., Halling, S.M. Appl. Environ. Microbiol. (1994) [Pubmed]
  14. Evidence that the reaction of the UDP-N-acetylglucosamine 1-carboxyvinyltransferase proceeds through the O-phosphothioketal of pyruvic acid bound to Cys115 of the enzyme. Wanke, C., Amrhein, N. Eur. J. Biochem. (1993) [Pubmed]
  15. Construction and vaccine potential of an aroA mutant of Pasteurella haemolytica. Homchampa, P., Strugnell, R.A., Adler, B. Vet. Microbiol. (1994) [Pubmed]
  16. Molecular cloning and sequencing of the aroA gene from Actinobacillus pleuropneumoniae and its use in a PCR assay for rapid identification. Hernanz Moral, C., Cascón Soriano, A., Sánchez Salazar, M., Yugueros Marcos, J., Suárez Ramos, S., Naharro Carrasco, G. J. Clin. Microbiol. (1999) [Pubmed]
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