Gene Review:
BAIAP2 - BAI1-associated protein 2
Homo sapiens
Synonyms:
BAI-associated protein 2, BAP2, Brain-specific angiogenesis inhibitor 1-associated protein 2, FLAF3, Fas ligand-associated factor 3, ...
- A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein. Yamagishi, A., Masuda, M., Ohki, T., Onishi, H., Mochizuki, N. J. Biol. Chem. (2004)
- IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasiveness. Funato, Y., Terabayashi, T., Suenaga, N., Seiki, M., Takenawa, T., Miki, H. Cancer Res. (2004)
- WAVE2 signaling mediates invasion of polarized epithelial cells by Salmonella typhimurium. Shi, J., Scita, G., Casanova, J.E. J. Biol. Chem. (2005)
- Maize endosperm secretes a novel antifungal protein into adjacent maternal tissue. Serna, A., Maitz, M., O'Connell, T., Santandrea, G., Thevissen, K., Tienens, K., Hueros, G., Faleri, C., Cai, G., Lottspeich, F., Thompson, R.D. Plant J. (2001)
- Missing-in-metastasis and IRSp53 deform PI(4,5)P2-rich membranes by an inverse BAR domain-like mechanism. Mattila, P.K., Pykäläinen, A., Saarikangas, J., Paavilainen, V.O., Vihinen, H., Jokitalo, E., Lappalainen, P. J. Cell Biol. (2007)
- Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac. Suetsugu, S., Kurisu, S., Oikawa, T., Yamazaki, D., Oda, A., Takenawa, T. J. Cell Biol. (2006)
- Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53. Millard, T.H., Bompard, G., Heung, M.Y., Dafforn, T.R., Scott, D.J., Machesky, L.M., Fütterer, K. EMBO J. (2005)
- Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1. Oda, K., Shiratsuchi, T., Nishimori, H., Inazawa, J., Yoshikawa, H., Taketani, Y., Nakamura, Y., Tokino, T. Cytogenet. Cell Genet. (1999)
- Cdc42Hs facilitates cytoskeletal reorganization and neurite outgrowth by localizing the 58-kD insulin receptor substrate to filamentous actin. Govind, S., Kozma, R., Monfries, C., Lim, L., Ahmed, S. J. Cell Biol. (2001)
- The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses. Abbott, M.A., Wells, D.G., Fallon, J.R. J. Neurosci. (1999)
- Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex. Krugmann, S., Jordens, I., Gevaert, K., Driessens, M., Vandekerckhove, J., Hall, A. Curr. Biol. (2001)
- Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2. Fujiwara, T., Mammoto, A., Kim, Y., Takai, Y. Biochem. Biophys. Res. Commun. (2000)
- Dentatorubral-pallidoluysian atrophy protein interacts through a proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate. Okamura-Oho, Y., Miyashita, T., Ohmi, K., Yamada, M. Hum. Mol. Genet. (1999)
- The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42. Soltau, M., Richter, D., Kreienkamp, H.J. Mol. Cell. Neurosci. (2002)
- MALS is a binding partner of IRSp53 at cell-cell contacts. Hori, K., Konno, D., Maruoka, H., Sobue, K. FEBS Lett. (2003)
- Insulin receptor substrate of 53 kDa links postsynaptic shank to PSD-95. Soltau, M., Berhörster, K., Kindler, S., Buck, F., Richter, D., Kreienkamp, H.J. J. Neurochem. (2004)