Gene Review:
Gnao1 - guanine nucleotide binding protein, alpha O
Mus musculus
Synonyms:
AW050213, Galphao, Gna0, Gnao, Go alpha, ...
- Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain. Itoh, H., Kozasa, T., Nagata, S., Nakamura, S., Katada, T., Ui, M., Iwai, S., Ohtsuka, E., Kawasaki, H., Suzuki, K. Proc. Natl. Acad. Sci. U.S.A. (1986)
- Immunochemical and electrophoretic characterization of the major pertussis toxin substrate of the RAW264 macrophage cell line. Backlund, P.S., Aksamit, R.R., Unson, C.G., Goldsmith, P., Spiegel, A.M., Milligan, G. Biochemistry (1988)
- Specific antibodies against Go isoforms reveal the early expression of the Go2 alpha subunit and appearance of Go1 alpha during neuronal differentiation. Rouot, B., Charpentier, N., Chabbert, C., Carrette, J., Zumbihl, R., Bockaert, J., Homburger, V. Mol. Pharmacol. (1992)
- Multiple species and isoforms of Bordetella pertussis toxin substrates. Brabet, P., Pantaloni, C., Rouot, B., Toutant, M., Garcia-Sainz, A., Bockaert, J., Homburger, V. Biochem. Biophys. Res. Commun. (1988)
- Alternative splicing produces transcripts encoding two forms of the alpha subunit of GTP-binding protein Go. Strathmann, M., Wilkie, T.M., Simon, M.I. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Different forms of Go alpha mRNA arise by alternative splicing of transcripts from a single gene on human chromosome 16. Murtagh, J.J., Eddy, R., Shows, T.B., Moss, J., Vaughan, M. Mol. Cell. Biol. (1991)
- Apical localization of the alpha subunit of GTP-binding protein Go in choroidal and ciliated ependymocytes. Péraldi, S., Nguyen Than Dao, B., Brabet, P., Homburger, V., Rouot, B., Toutant, M., Bouille, C., Assenmacher, I., Bockaert, J., Gabrion, J. J. Neurosci. (1989)
- Structural and functional characterization of guanyl nucleotide-binding proteins using monoclonal antibodies to the alpha-subunit of transducin. Halpern, J.L., Tsai, S.C., Adamik, R., Kanaho, Y., Bekesi, E., Kung, H.F., Moss, J., Vaughan, M. Mol. Pharmacol. (1986)
- Metabolism of two Go alpha isoforms in neuronal cells during differentiation. Brabet, P., Pantaloni, C., Bockaert, J., Homburger, V. J. Biol. Chem. (1991)
- Immunocytochemical localization of the guanine nucleotide-binding protein Go in primary cultures of neuronal and glial cells. Brabet, P., Dumuis, A., Sebben, M., Pantaloni, C., Bockaert, J., Homburger, V. J. Neurosci. (1988)
- Pertussis toxin treatment in vivo is associated with a decline in G-protein beta-subunits. Watkins, D.C., Northup, J.K., Malbon, C.C. J. Biol. Chem. (1989)
- Myr+-Gi2 alpha and Go alpha subunits restore the efficacy of opioids, clonidine and neurotensin giving rise to antinociception in G-protein knock-down mice. Garzón, J., Rodríguez-Díaz, M., DeAntonio, I., DeFelipe, J., Rodríguez, J.R., Sánchez-Blázquez, P. Neuropharmacology (1999)
- Mastoparan reduces the supraspinal analgesia mediated by mu/delta-opioid receptors in mice. Sánchez-Blázquez, P., Garzón, J. Eur. J. Pharmacol. (1994)
- Treatment of intact striatal neurones with cholera toxin or 8-bromoadenosine 3',5'-(cyclic)phosphate decreases the ability of pertussis toxin to ADP-ribosylate the alpha-subunits of inhibitory and other guanine-nucleotide-binding regulatory proteins, Gi and Go. Evidence for two distinct mechanisms. Maus, M., Homburger, V., Cordier, J., Pantaloni, C., Bockaert, J., Glowinski, J., Prémont, J. Eur. J. Biochem. (1991)
- Ontogeny of pulmonary neuroendocrine cells which express the alpha-subunit of guanine nucleotide-binding protein Go. Ito, T., Udaka, N., Kawano, N., Nogawa, H., Kitamura, H. Histochem. Cell Biol. (1999)
- Relationships within the family of GTP-binding proteins isolated from bovine central nervous system. Roof, D.J., Applebury, M.L., Sternweis, P.C. J. Biol. Chem. (1985)
- Deletion within the amino-terminal region of Gs alpha impairs its ability to interact with beta gamma subunits and to activate adenylate cyclase. Journot, L., Pantaloni, C., Bockaert, J., Audigier, Y. J. Biol. Chem. (1991)
- Morphological and functional characterization of beta TC-6 cells--an insulin-secreting cell line derived from transgenic mice. Poitout, V., Stout, L.E., Armstrong, M.B., Walseth, T.F., Sorenson, R.L., Robertson, R.P. Diabetes (1995)
- Possible involvement of phosphatidylinositol-specific phospholipase C related to pertussis toxin-sensitive GTP-binding proteins during adipocyte differentiation of 3T3-L1 fibroblasts: negative regulation of protein kinase C. Uehara, T., Hoshino, S., Ui, M., Tokumitsu, Y., Nomura, Y. Biochim. Biophys. Acta (1994)