Gene Review:
Vldlr - very low density lipoprotein receptor
Mus musculus
Synonyms:
AA408956, AI451093, AW047288, VLDL receptor, VLDL-R, ...
- Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor. Kobayashi, K., Oka, K., Forte, T., Ishida, B., Teng, B., Ishimura-Oka, K., Nakamuta, M., Chan, L. J. Biol. Chem. (1996)
- Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus-mediated transfer of the VLDL receptor gene. Kozarsky, K.F., Jooss, K., Donahee, M., Strauss, J.F., Wilson, J.M. Nat. Genet. (1996)
- Changes in cardiac lipid metabolism during sepsis: the essential role of very low-density lipoprotein receptors. Jia, L., Takahashi, M., Morimoto, H., Takahashi, S., Izawa, A., Ise, H., Iwasaki, T., Hattori, H., Wu, K.J., Ikeda, U. Cardiovasc. Res. (2006)
- Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway. Niu, S., Renfro, A., Quattrocchi, C.C., Sheldon, M., D'Arcangelo, G. Neuron (2004)
- Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation. Hiesberger, T., Trommsdorff, M., Howell, B.W., Goffinet, A., Mumby, M.C., Cooper, J.A., Herz, J. Neuron (1999)
- The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor. Argraves, K.M., Kozarsky, K.F., Fallon, J.T., Harpel, P.C., Strickland, D.K. J. Clin. Invest. (1997)
- Regulation of Rac1 activation by the low density lipoprotein receptor-related protein. Ma, Z., Thomas, K.S., Webb, D.J., Moravec, R., Salicioni, A.M., Mars, W.M., Gonias, S.L. J. Cell Biol. (2002)
- Loss of VLDL receptor activates retinal vascular endothelial cells and promotes angiogenesis. Jiang, A.H., Hu, W., Meng, H., Gao, H., Qiao, X. Invest. Ophthalmol. Vis. Sci. (2008)
- Protection from obesity in mice lacking the VLDL receptor. Goudriaan, J.R., Tacken, P.J., Dahlmans, V.E., Gijbels, M.J., van Dijk, K.W., Havekes, L.M., Jong, M.C. Arterioscler. Thromb. Vasc. Biol. (2001)
- Expression of VLDLR in the retina and evolution of subretinal neovascularization in the knockout mouse model's retinal angiomatous proliferation. Hu, W., Jiang, A., Liang, J., Meng, H., Chang, B., Gao, H., Qiao, X. Invest. Ophthalmol. Vis. Sci. (2008)
- Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse. Pilz, A., Woodward, K., Povey, S., Abbott, C. Genomics (1995)
- The mouse very low density lipoprotein receptor (Vldlr) gene maps to chromosome 19. Naggert, J.K., Mu, J.L. Mamm. Genome (1994)
- Upregulation of liver VLDL receptor and FAT/CD36 expression in LDLR-/- apoB100/100 mice fed trans-10,cis-12 conjugated linoleic acid. Degrace, P., Moindrot, B., Mohamed, I., Gresti, J., Du, Z.Y., Chardigny, J.M., S??b??dio, J.L., Clouet, P. J. Lipid Res. (2006)
- Mouse very-low-density-lipoprotein receptor (VLDLR) cDNA cloning, tissue-specific expression and evolutionary relationship with the low-density-lipoprotein receptor. Oka, K., Ishimura-Oka, K., Chu, M.J., Sullivan, M., Krushkal, J., Li, W.H., Chan, L. Eur. J. Biochem. (1994)
- LDL receptor deficiency unmasks altered VLDL triglyceride metabolism in VLDL receptor transgenic and knockout mice. Tacken, P.J., Teusink, B., Jong, M.C., Harats, D., Havekes, L.M., van Dijk, K.W., Hofker, M.H. J. Lipid Res. (2000)
- Mouse very low-density lipoprotein receptor (VLDLR): gene structure, tissue-specific expression and dietary and developmental regulation. Tiebel, O., Oka, K., Robinson, K., Sullivan, M., Martinez, J., Nakamuta, M., Ishimura-Oka, K., Chan, L. Atherosclerosis (1999)
- Malformation of the radial glial scaffold in the dentate gyrus of reeler mice, scrambler mice, and ApoER2/VLDLR-deficient mice. Weiss, K.H., Johanssen, C., Tielsch, A., Herz, J., Deller, T., Frotscher, M., Förster, E. J. Comp. Neurol. (2003)
- Identification and characterization of a very low density lipoprotein receptor-binding peptide from tissue factor pathway inhibitor that has antitumor and antiangiogenic activity. Hembrough, T.A., Ruiz, J.F., Swerdlow, B.M., Swartz, G.M., Hammers, H.J., Zhang, L., Plum, S.M., Williams, M.S., Strickland, D.K., Pribluda, V.S. Blood (2004)
- Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor. Jong, M.C., van Dijk, K.W., Dahlmans, V.E., Van der Boom, H., Kobayashi, K., Oka, K., Siest, G., Chan, L., Hofker, M.H., Havekes, L.M. Biochem. J. (1999)
- Binding of purified Reelin to ApoER2 and VLDLR mediates tyrosine phosphorylation of Disabled-1. Benhayon, D., Magdaleno, S., Curran, T. Brain Res. Mol. Brain Res. (2003)
- Aggressive very low-density lipoprotein (VLDL) and LDL lowering by gene transfer of the VLDL receptor combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor-deficient mice. MacDougall, E.D., Kramer, F., Polinsky, P., Barnhart, S., Askari, B., Johansson, F., Varon, R., Rosenfeld, M.E., Oka, K., Chan, L., Schwartz, S.M., Bornfeldt, K.E. Am. J. Pathol. (2006)
- NMDA-receptor proteins are upregulated in the hippocampus of postnatal heterozygous reeler mice. Isosaka, T., Hattori, K., Yagi, T. Brain Res. (2006)
- Reelin activates SRC family tyrosine kinases in neurons. Bock, H.H., Herz, J. Curr. Biol. (2003)
- Dentate granule cells in reeler mutants and VLDLR and ApoER2 knockout mice. Drakew, A., Deller, T., Heimrich, B., Gebhardt, C., Del Turco, D., Tielsch, A., Förster, E., Herz, J., Frotscher, M. Exp. Neurol. (2002)
- Reelin signaling is necessary for a specific step in the migration of hindbrain efferent neurons. Rossel, M., Loulier, K., Feuillet, C., Alonso, S., Carroll, P. Development (2005)
- Differential binding of ligands to the apolipoprotein E receptor 2. Andersen, O.M., Benhayon, D., Curran, T., Willnow, T.E. Biochemistry (2003)
- Expression of the VLDL receptor in endothelial cells. Wyne, K.L., Pathak, K., Seabra, M.C., Hobbs, H.H. Arterioscler. Thromb. Vasc. Biol. (1996)
- Role of VLDL receptor in the process of foam cell formation. Qu, S., Wu, F., Tian, J., Li, Y., Wang, Y., Wang, Y., Zong, Y. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. (2004)