Gene Review:
MMP19 - matrix metallopeptidase 19
Homo sapiens
Synonyms:
MMP-18, MMP-19, MMP18, Matrix metalloproteinase RASI, Matrix metalloproteinase-18, ...
- Identification and characterization of a novel human matrix metalloproteinase with unique structural characteristics, chromosomal location, and tissue distribution. Pendás, A.M., Knäuper, V., Puente, X.S., Llano, E., Mattei, M.G., Apte, S., Murphy, G., López-Otín, C. J. Biol. Chem. (1997)
- Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer. Impola, U., Uitto, V.J., Hietanen, J., Hakkinen, L., Zhang, L., Larjava, H., Isaka, K., Saarialho-Kere, U. J. Pathol. (2004)
- Matrix metalloproteinase-19 is expressed by proliferating epithelium but disappears with neoplastic dedifferentiation. Impola, U., Toriseva, M., Suomela, S., Jeskanen, L., Hieta, N., Jahkola, T., Grenman, R., Kähäri, V.M., Saarialho-Kere, U. Int. J. Cancer (2003)
- Earlier onset of tumoral angiogenesis in matrix metalloproteinase-19-deficient mice. Jost, M., Folgueras, A.R., Frérart, F., Pendas, A.M., Blacher, S., Houard, X., Berndt, S., Munaut, C., Cataldo, D., Alvarez, J., Melen-Lamalle, L., Foidart, J.M., López-Otín, C., Noël, A. Cancer Res. (2006)
- Matrix metalloproteinase 19 regulates insulin-like growth factor-mediated proliferation, migration, and adhesion in human keratinocytes through proteolysis of insulin-like growth factor binding protein-3. Sadowski, T., Dietrich, S., Koschinsky, F., Sedlacek, R. Mol. Biol. Cell (2003)
- Cloning and characterization of a novel matrix metalloproteinase (MMP), CMMP, from chicken embryo fibroblasts. CMMP, Xenopus XMMP, and human MMP19 have a conserved unique cysteine in the catalytic domain. Yang, M., Kurkinen, M. J. Biol. Chem. (1998)
- Biochemical characterization of the catalytic domain of human matrix metalloproteinase 19. Evidence for a role as a potent basement membrane degrading enzyme. Stracke, J.O., Hutton, M., Stewart, M., Pendás, A.M., Smith, B., López-Otin, C., Murphy, G., Knäuper, V. J. Biol. Chem. (2000)
- Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP). Stracke, J.O., Fosang, A.J., Last, K., Mercuri, F.A., Pendás, A.M., Llano, E., Perris, R., Di Cesare, P.E., Murphy, G., Knäuper, V. FEBS Lett. (2000)
- Matrix metalloproteinase-19 is expressed in myeloid cells in an adhesion-dependent manner and associates with the cell surface. Mauch, S., Kolb, C., Kolb, B., Sadowski, T., Sedlacek, R. J. Immunol. (2002)
- Matrix metalloproteinase 19 processes the laminin 5 gamma 2 chain and induces epithelial cell migration. Sadowski, T., Dietrich, S., Koschinsky, F., Ludwig, A., Proksch, E., Titz, B., Sedlacek, R. Cell. Mol. Life Sci. (2005)
- Matrix metalloproteinase-19 expression in normal and diseased skin: dysregulation by epidermal proliferation. Sadowski, T., Dietrich, S., Müller, M., Havlickova, B., Schunck, M., Proksch, E., Müller, M.S., Sedlacek, R. J. Invest. Dermatol. (2003)
- Matrix metalloproteinase MMP-19 (RASI-1) is expressed on the surface of activated peripheral blood mononuclear cells and is detected as an autoantigen in rheumatoid arthritis. Sedlacek, R., Mauch, S., Kolb, B., Schätzlein, C., Eibel, H., Peter, H.H., Schmitt, J., Krawinkel, U. Immunobiology (1998)
- Activity of MMP-19 inhibits capillary-like formation due to processing of nidogen-1. Titz, B., Dietrich, S., Sadowski, T., Beck, C., Petersen, A., Sedlacek, R. Cell. Mol. Life Sci. (2004)
- The matrix metalloproteinase RASI-1 is expressed in synovial blood vessels of a rheumatoid arthritis patient. Kolb, C., Mauch, S., Peter, H.H., Krawinkel, U., Sedlacek, R. Immunol. Lett. (1997)
- MMP-19: cellular localization of a novel metalloproteinase within normal breast tissue and mammary gland tumours. Djonov, V., Högger, K., Sedlacek, R., Laissue, J., Draeger, A. J. Pathol. (2001)
- Matrilysins-1 and -2 (MMP-7 and -26) and metalloelastase (MMP-12), unlike MMP-19, are up-regulated in necrotizing enterocolitis. Bister, V., Salmela, M.T., Heikkilä, P., Anttila, A., Rintala, R., Isaka, K., Andersson, S., Saarialho-Kere, U. J. Pediatr. Gastroenterol. Nutr. (2005)
- Structural characterization and binding properties of the hemopexin-like domain of the matrixmetalloproteinase-19. Mysliwy, J., Dingley, A.J., Sedlacek, R., Grötzinger, J. Protein Expr. Purif. (2006)
- Transformation-specific matrix metalloproteinases, MMP-7 and MMP-13, are present in epithelial cells of keratoacanthomas. Kuivanen, T.T., Jeskanen, L., Kyllönen, L., Impola, U., Saarialho-Kere, U.K. Mod. Pathol. (2006)
- Matrix metalloproteinase-19 in capillary endothelial cells: expression in acutely, but not in chronically, inflamed synovium. Kolb, C., Mauch, S., Krawinkel, U., Sedlacek, R. Exp. Cell Res. (1999)
- Matrix metalloproteinase-19 expression in dermal wounds and by fibroblasts in culture. Hieta, N., Impola, U., López-Otín, C., Saarialho-Kere, U., Kähäri, V.M. J. Invest. Dermatol. (2003)