Gene Review:
PPP4C - protein phosphatase 4, catalytic subunit
Homo sapiens
Synonyms:
PP-X, PP4, PP4C, PPH3, PPP4, ...
- PPX, a novel protein serine/threonine phosphatase localized to centrosomes. Brewis, N.D., Street, A.J., Prescott, A.R., Cohen, P.T. EMBO J. (1993)
- Protein phosphatase X has been highly conserved during mammalian evolution. Brewis, N.D., Cohen, P.T. Biochim. Biophys. Acta (1992)
- The bvg-dependent promoters show similar behaviour in different Bordetella species and share sequence homologies. Scarlato, V., Prugnola, A., Aricò, B., Rappuoli, R. Mol. Microbiol. (1991)
- A phase I and pharmacokinetic study of paclitaxel poliglumex (XYOTAX), investigating both 3-weekly and 2-weekly schedules. Boddy, A.V., Plummer, E.R., Todd, R., Sludden, J., Griffin, M., Robson, L., Cassidy, J., Bissett, D., Bernareggi, A., Verrill, M.W., Calvert, A.H. Clin. Cancer Res. (2005)
- Paclitaxel poliglumex (XYOTAX, CT-2103): a macromolecular taxane. Singer, J.W. Journal of controlled release : official journal of the Controlled Release Society. (2005)
- Protein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation. Mihindukulasuriya, K.A., Zhou, G., Qin, J., Tan, T.H. J. Biol. Chem. (2004)
- Protein phosphatase 4 is a positive regulator of hematopoietic progenitor kinase 1. Zhou, G., Boomer, J.S., Tan, T.H. J. Biol. Chem. (2004)
- Continuous interscalene analgesia with ropivacaine 2 mg/ml after major shoulder surgery. Ekatodramis, G., Borgeat, A., Huledal, G., Jeppsson, L., Westman, L., Sjövall, J. Anesthesiology (2003)
- Role of the phosphatase PP4 in the activation of JNK-1 in prostate carcinoma cell lines PC-3 and LNCaP resulting in increased AP-1 and EGR-1 activity. Inostroza, J., Sáenz, L., Calaf, G., Cabello, G., Parra, E. Biol. Res. (2005)
- Inhibition of several protein phosphatases by a non-covalently interacting microcystin and a novel cyanobacterial peptide, nostocyclin. Hastie, C.J., Borthwick, E.B., Morrison, L.F., Codd, G.A., Cohen, P.T. Biochim. Biophys. Acta (2005)
- Assignment of the human serine/threonine protein phosphatase 4 gene (PPP4C) to chromosome 16p11-p12 by fluorescence in situ hybridization. Bastians, H., Krebber, H., Hoheisel, J., Ohl, S., Lichter, P., Ponstingl, H., Joos, S. Genomics (1997)
- Purification and identification of a novel subunit of protein serine/threonine phosphatase 4. Kloeker, S., Wadzinski, B.E. J. Biol. Chem. (1999)
- Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-kappaB activation by protein phosphatase 4-mediated NF-kappaB p65 Thr dephosphorylation. Yeh, P.Y., Yeh, K.H., Chuang, S.E., Song, Y.C., Cheng, A.L. J. Biol. Chem. (2004)
- Purification of protein phosphatase 4 catalytic subunit: inhibition by the antitumour drug fostriecin and other tumour suppressors and promoters. Hastie, C.J., Cohen, P.T. FEBS Lett. (1998)
- Carboxymethylation of nuclear protein serine/threonine phosphatase X. Kloeker, S., Bryant, J.C., Strack, S., Colbran, R.J., Wadzinski, B.E. Biochem. J. (1997)
- Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17. Pandey, A.V., Mellon, S.H., Miller, W.L. J. Biol. Chem. (2003)
- Effect of rifampin and tobacco smoking on the pharmacokinetics of ropivacaine. Jokinen, M.J., Olkkola, K.T., Ahonen, J., Neuvonen, P.J. Clin. Pharmacol. Ther. (2001)
- A novel 50 kDa protein forms complexes with protein phosphatase 4 and is located at centrosomal microtubule organizing centres. Hastie, C.J., Carnegie, G.K., Morrice, N., Cohen, P.T. Biochem. J. (2000)
- Protein phosphatase 4 is involved in tumor necrosis factor-alpha-induced activation of c-Jun N-terminal kinase. Zhou, G., Mihindukulasuriya, K.A., MacCorkle-Chosnek, R.A., Van Hooser, A., Hu, M.C., Brinkley, B.R., Tan, T.H. J. Biol. Chem. (2002)
- Metabolism and excretion of ropivacaine in humans. Halldin, M.M., Bredberg, E., Angelin, B., Arvidsson, T., Askemark, Y., Elofsson, S., Widman, M. Drug Metab. Dispos. (1996)
- Lack of metabolic racemisation of ropivacaine, determined by liquid chromatography using a chiral AGP column. Arvidsson, T., Bruce, H.F., Halldin, M.M. Chirality. (1995)
- Utility of routine pelvic X-ray during blunt trauma resuscitation. Gillott, A., Rhodes, M., Lucke, J. The Journal of trauma. (1988)