Gene Review:
TRPC3 - transient receptor potential cation...
Homo sapiens
Synonyms:
Short transient receptor potential channel 3, TRP-3, TRP3, Transient receptor protein 3, TrpC3, ...
- Role of transient receptor potential C3 in TNF-alpha-enhanced calcium influx in human airway myocytes. White, T.A., Xue, A., Chini, E.N., Thompson, M., Sieck, G.C., Wylam, M.E. Am. J. Respir. Cell Mol. Biol. (2006)
- VAMP2-dependent exocytosis regulates plasma membrane insertion of TRPC3 channels and contributes to agonist-stimulated Ca2+ influx. Singh, B.B., Lockwich, T.P., Bandyopadhyay, B.C., Liu, X., Bollimuntha, S., Brazer, S.C., Combs, C., Das, S., Leenders, A.G., Sheng, Z.H., Knepper, M.A., Ambudkar, S.V., Ambudkar, I.S. Mol. Cell (2004)
- Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension. Yu, Y., Fantozzi, I., Remillard, C.V., Landsberg, J.W., Kunichika, N., Platoshyn, O., Tigno, D.D., Thistlethwaite, P.A., Rubin, L.J., Yuan, J.X. Proc. Natl. Acad. Sci. U.S.A. (2004)
- TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy. Onohara, N., Nishida, M., Inoue, R., Kobayashi, H., Sumimoto, H., Sato, Y., Mori, Y., Nagao, T., Kurose, H. EMBO J. (2006)
- Receptor-coupled, DAG-gated Ca2+-permeable cationic channels in LNCaP human prostate cancer epithelial cells. Sydorenko, V., Shuba, Y., Thebault, S., Roudbaraki, M., Lepage, G., Prevarskaya, N., Skryma, R. J. Physiol. (Lond.) (2003)
- A C. elegans sperm TRP protein required for sperm-egg interactions during fertilization. Xu, X.Z., Sternberg, P.W. Cell (2003)
- trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry. Zhu, X., Jiang, M., Peyton, M., Boulay, G., Hurst, R., Stefani, E., Birnbaumer, L. Cell (1996)
- Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Hofmann, T., Obukhov, A.G., Schaefer, M., Harteneck, C., Gudermann, T., Schultz, G. Nature (1999)
- A functional link between store-operated and TRPC channels revealed by the 3,5-bis(trifluoromethyl)pyrazole derivative, BTP2. He, L.P., Hewavitharana, T., Soboloff, J., Spassova, M.A., Gill, D.L. J. Biol. Chem. (2005)
- Store-operated Ca2+ entry in first trimester and term human placenta. Clarson, L.H., Roberts, V.H., Hamark, B., Elliott, A.C., Powell, T. J. Physiol. (Lond.) (2003)
- Regulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G. Kwan, H.Y., Huang, Y., Yao, X. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Cytoskeletal reorganization internalizes multiple transient receptor potential channels and blocks calcium entry into human neutrophils. Itagaki, K., Kannan, K.B., Singh, B.B., Hauser, C.J. J. Immunol. (2004)
- TRPC3 mediates T-cell receptor-dependent calcium entry in human T-lymphocytes. Philipp, S., Strauss, B., Hirnet, D., Wissenbach, U., Mery, L., Flockerzi, V., Hoth, M. J. Biol. Chem. (2003)
- Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx. Bandyopadhyay, B.C., Swaim, W.D., Liu, X., Redman, R.S., Patterson, R.L., Ambudkar, I.S. J. Biol. Chem. (2005)
- Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor- and store-operated Ca2+ entry channels. Kawasaki, B.T., Liao, Y., Birnbaumer, L. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Molecular cloning of TRPC3a, an N-terminally extended, store-operated variant of the human C3 transient receptor potential channel. Yildirim, E., Kawasaki, B.T., Birnbaumer, L. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Endogenous TRPC1, TRPC3, and TRPC7 proteins combine to form native store-operated channels in HEK-293 cells. Zagranichnaya, T.K., Wu, X., Villereal, M.L. J. Biol. Chem. (2005)
- Transient receptor potential protein subunit assembly and membrane distribution in human platelets. Brownlow, S.L., Sage, S.O. Thromb. Haemost. (2005)
- Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel. Heteromeric assembly of TRPC1-TRPC3. Liu, X., Bandyopadhyay, B.C., Singh, B.B., Groschner, K., Ambudkar, I.S. J. Biol. Chem. (2005)
- Ca(2+) signaling by TRPC3 involves Na(+) entry and local coupling to the Na(+)/Ca(2+) exchanger. Rosker, C., Graziani, A., Lukas, M., Eder, P., Zhu, M.X., Romanin, C., Groschner, K. J. Biol. Chem. (2004)
- A calmodulin/inositol 1,4,5-trisphosphate (IP3) receptor-binding region targets TRPC3 to the plasma membrane in a calmodulin/IP3 receptor-independent process. Wedel, B.J., Vazquez, G., McKay, R.R., St J Bird, G., Putney, J.W. J. Biol. Chem. (2003)
- Structural Characterization of the Split Pleckstrin Homology Domain in Phospholipase C-{gamma}1 and Its Interaction with TRPC3. Wen, W., Yan, J., Zhang, M. J. Biol. Chem. (2006)
- Identification and localization of TRPC channels in the rat kidney. Goel, M., Sinkins, W.G., Zuo, C.D., Estacion, M., Schilling, W.P. Am. J. Physiol. Renal Physiol. (2006)
- VEGF activates receptor-operated cation channels in human microvascular endothelial cells. Cheng, H.W., James, A.F., Foster, R.R., Hancox, J.C., Bates, D.O. Arterioscler. Thromb. Vasc. Biol. (2006)
- TRPC3 and TRPC4 Associate to Form a Redox-sensitive Cation Channel: EVIDENCE FOR EXPRESSION OF NATIVE TRPC3-TRPC4 HETEROMERIC CHANNELS IN ENDOTHELIAL CELLS. Poteser, M., Graziani, A., Rosker, C., Eder, P., Derler, I., Kahr, H., Zhu, M.X., Romanin, C., Groschner, K. J. Biol. Chem. (2006)
- Functional coupling between TRPC3 and RyR1 regulates the expressions of key triadic proteins. Lee, E.H., Cherednichenko, G., Pessah, I.N., Allen, P.D. J. Biol. Chem. (2006)
- TRPC3 is the erythropoietin-regulated calcium channel in human erythroid cells. Tong, Q., Hirschler-Laszkiewicz, I., Zhang, W., Conrad, K., Neagley, D.W., Barber, D.L., Cheung, J.Y., Miller, B.A. J. Biol. Chem. (2008)
- Specific association of the gene product of PKD2 with the TRPC1 channel. Tsiokas, L., Arnould, T., Zhu, C., Kim, E., Walz, G., Sukhatme, V.P. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Association of immunophilins with mammalian TRPC channels. Sinkins, W.G., Goel, M., Estacion, M., Schilling, W.P. J. Biol. Chem. (2004)
- TRP channels in lymphocytes. Schwarz, E.C., Wolfs, M.J., Tonner, S., Wenning, A.S., Quintana, A., Griesemer, D., Hoth, M. Handbook of experimental pharmacology (2007)
- TRPC3 activation by erythropoietin is modulated by TRPC6. Hirschler-Laszkiewicz, I., Tong, Q., Conrad, K., Zhang, W., Flint, W.W., Barber, A.J., Barber, D.L., Cheung, J.Y., Miller, B.A. J. Biol. Chem. (2009)
- Plasticity of TRPC expression in arterial smooth muscle: correlation with store-operated Ca2+ entry. Bergdahl, A., Gomez, M.F., Wihlborg, A.K., Erlinge, D., Eyjolfson, A., Xu, S.Z., Beech, D.J., Dreja, K., Hellstrand, P. Am. J. Physiol., Cell Physiol. (2005)
- Functional significance of human trp1 and trp3 in store-operated Ca(2+) entry in HEK-293 cells. Wu, X., Babnigg, G., Villereal, M.L. Am. J. Physiol., Cell Physiol. (2000)
- Negative regulation of TRPC3 channels by protein kinase C-mediated phosphorylation of serine 712. Trebak, M., Hempel, N., Wedel, B.J., Smyth, J.T., Bird, G.S., Putney, J.W. Mol. Pharmacol. (2005)