Gene Review:
SLC8A1 - solute carrier family 8 (sodium/calcium...
Homo sapiens
Synonyms:
CNC, NCX1, Na(+)/Ca(2+)-exchange protein 1, Sodium/calcium exchanger 1, Solute carrier family 8 member 1
- Association of genetic polymorphisms of sodium-calcium exchanger 1 gene, NCX1, with hypertension in a Japanese general population. Kokubo, Y., Inamoto, N., Tomoike, H., Kamide, K., Takiuchi, S., Kawano, Y., Tanaka, C., Katanosaka, Y., Wakabayashi, S., Shigekawa, M., Hishikawa, O., Miyata, T. Hypertens. Res. (2004)
- Identification and characterization of a sodium/calcium exchanger, NCX-1, in osteoclasts and its role in bone resorption. Moonga, B.S., Davidson, R., Sun, L., Adebanjo, O.A., Moser, J., Abedin, M., Zaidi, N., Huang, C.L., Zaidi, M. Biochem. Biophys. Res. Commun. (2001)
- Selective alteration of expression of Na+/Ca2+ exchanger isoforms after transient focal cerebral ischemia in rats. Li, L.L., Sun, L.N., Zhou, H.Y., Li, Z.B., Wang, X.L. Neurosci. Lett. (2006)
- Metabolic regulation of sodium-calcium exchange by intracellular acyl CoAs. Riedel, M.J., Baczk??, I., Searle, G.J., Webster, N., Fercho, M., Jones, L., Lang, J., Lytton, J., Dyck, J.R., Light, P.E. EMBO J. (2006)
- Calcium extrusion is critical for cardiac morphogenesis and rhythm in embryonic zebrafish hearts. Ebert, A.M., Hume, G.L., Warren, K.S., Cook, N.P., Burns, C.G., Mohideen, M.A., Siegal, G., Yelon, D., Fishman, M.C., Garrity, D.M. Proc. Natl. Acad. Sci. U.S.A. (2005)
- HiResolution and conventional sound processing in the HiResolution bionic ear: using appropriate outcome measures to assess speech recognition ability. Koch, D.B., Osberger, M.J., Segel, P., Kessler, D. Audiol. Neurootol. (2004)
- Conserved noncoding sequences are selectively constrained and not mutation cold spots. Drake, J.A., Bird, C., Nemesh, J., Thomas, D.J., Newton-Cheh, C., Reymond, A., Excoffier, L., Attar, H., Antonarakis, S.E., Dermitzakis, E.T., Hirschhorn, J.N. Nat. Genet. (2006)
- Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smooth muscle. Iwamoto, T., Kita, S., Zhang, J., Blaustein, M.P., Arai, Y., Yoshida, S., Wakimoto, K., Komuro, I., Katsuragi, T. Nat. Med. (2004)
- Differential distribution of NCX1 contributes to spine-dendrite compartmentalization in CA1 pyramidal cells. Lörincz, A., Rózsa, B., Katona, G., Vizi, E.S., Tamás, G. Proc. Natl. Acad. Sci. U.S.A. (2007)
- Involvement of Na+-Ca2+ exchanger in intracellular Ca2+ increase and neuronal injury induced by polychlorinated biphenyls in human neuroblastoma SH-SY5Y cells. Magi, S., Castaldo, P., Carrieri, G., Scorziello, A., Di Renzo, G., Amoroso, S. J. Pharmacol. Exp. Ther. (2005)
- Cyclosporin A regulates sodium-calcium exchanger (NCX1) gene expression in vitro and cardiac hypertrophy in NCX1 transgenic mice. Jordan, M.C., Quednau, B.D., Roos, K.P., Ross, R.S., Philipson, K.D., Nicholas, S.B. Ann. N. Y. Acad. Sci. (2002)
- On titanium frameworks and alternative impression techniques in implant dentistry. Ortorp, A. Swedish dental journal. Supplement. (2005)
- Stoichiometry of the Cardiac Na+/Ca2+ exchanger NCX1.1 measured in transfected HEK cells. Dong, H., Dunn, J., Lytton, J. Biophys. J. (2002)
- The organization of the human gene NCX1 encoding the sodium-calcium exchanger. Kraev, A., Chumakov, I., Carafoli, E. Genomics (1996)
- Mapping of the gene for the cardiac sarcolemmal Na(+)-Ca2+ exchanger to human chromosome 2p21-p23. Shieh, B.H., Xia, Y., Sparkes, R.S., Klisak, I., Lusis, A.J., Nicoll, D.A., Philipson, K.D. Genomics (1992)
- Cloning of the multipartite promoter of the sodium-calcium exchanger gene NCX1 and characterization of its activity in vascular smooth muscle cells. Scheller, T., Kraev, A., Skinner, S., Carafoli, E. J. Biol. Chem. (1998)
- NCX1 Na/Ca exchanger splice variants in pancreatic islet cells. Van Eylen, F., Bollen, A., Herchuelz, A. J. Endocrinol. (2001)
- Plasma membrane-cytoskeleton-endoplasmic reticulum complexes in neurons and astrocytes. Lencesova, L., O'Neill, A., Resneck, W.G., Bloch, R.J., Blaustein, M.P. J. Biol. Chem. (2004)
- Phospholipase C-dependent control of cardiac calcium homeostasis involves a TRPC3-NCX1 signaling complex. Eder, P., Probst, D., Rosker, C., Poteser, M., Wolinski, H., Kohlwein, S.D., Romanin, C., Groschner, K. Cardiovasc. Res. (2007)
- Ca(2+) signaling by TRPC3 involves Na(+) entry and local coupling to the Na(+)/Ca(2+) exchanger. Rosker, C., Graziani, A., Lukas, M., Eder, P., Zhu, M.X., Romanin, C., Groschner, K. J. Biol. Chem. (2004)
- Heterogeneous transmural gene expression of calcium-handling proteins and natriuretic peptides in the failing human heart. Prestle, J., Dieterich, S., Preuss, M., Bieligk, U., Hasenfuss, G. Cardiovasc. Res. (1999)
- Evidence for cardiac sodium-calcium exchanger association with caveolin-3. Bossuyt, J., Taylor, B.E., James-Kracke, M., Hale, C.C. FEBS Lett. (2002)
- Inhibitory interaction of the plasma membrane Na+/Ca2+ exchangers with the 14-3-3 proteins. Pulina, M.V., Rizzuto, R., Brini, M., Carafoli, E. J. Biol. Chem. (2006)
- Cytoplasmic tail of phospholemman interacts with the intracellular loop of the cardiac na+/ca2+ exchanger. Wang, J., Zhang, X.Q., Ahlers, B.A., Carl, L.L., Song, J., Rothblum, L.I., Stahl, R.C., Carey, D.J., Cheung, J.Y. J. Biol. Chem. (2006)
- Disease-associated changes in the expression of ion channels, ion receptors, ion exchangers and Ca(2+)-handling proteins in heart hypertrophy. Zwadlo, C., Borlak, J. Toxicol. Appl. Pharmacol. (2005)
- Mapping of the human cardiac Na+/Ca2+ exchanger gene (NCX1) by fluorescent in situ hybridization to chromosome region 2p22-->p23. McDaniel, L.D., Lederer, W.J., Kofuji, P., Schulze, D.H., Kieval, R., Schultz, R.A. Cytogenet. Cell Genet. (1993)
- Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ. Lumsden, A.G. Development (1988)