Gene Review:
TRPC5 - transient receptor potential cation...
Homo sapiens
Synonyms:
PPP1R159, Short transient receptor potential channel 5, TRP-5, TRP5, Transient receptor protein 5, ...
- Capacitative Ca2+ entries and mRNA expression for TRPC1 and TRPC5 channels in human epidermoid carcinoma A431 cells. Yoshida, J., Ishibashi, T., Imaizumi, N., Takegami, T., Nishio, M. Eur. J. Pharmacol. (2005)
- Canonical Transient Receptor Potential Channels Promote Cardiomyocyte Hypertrophy through Activation of Calcineurin Signaling. Bush, E.W., Hood, D.B., Papst, P.J., Chapo, J.A., Minobe, W., Bristow, M.R., Olson, E.N., McKinsey, T.A. J. Biol. Chem. (2006)
- Canonical transient receptor potential 5. Beech, D.J. Handbook of experimental pharmacology (2007)
- Rapid vesicular translocation and insertion of TRP channels. Bezzerides, V.J., Ramsey, I.S., Kotecha, S., Greka, A., Clapham, D.E. Nat. Cell Biol. (2004)
- TRPC1 and TRPC5 form a novel cation channel in mammalian brain. Strübing, C., Krapivinsky, G., Krapivinsky, L., Clapham, D.E. Neuron (2001)
- Sensing of lysophospholipids by TRPC5 calcium channel. Flemming, P.K., Dedman, A.M., Xu, S.Z., Li, J., Zeng, F., Naylor, J., Benham, C.D., Bateson, A.N., Muraki, K., Beech, D.J. J. Biol. Chem. (2006)
- TRPC5 activation kinetics are modulated by the scaffolding protein ezrin/radixin/moesin-binding phosphoprotein-50 (EBP50). Obukhov, A.G., Nowycky, M.C. J. Cell. Physiol. (2004)
- Block of TRPC5 channels by 2-aminoethoxydiphenyl borate: a differential, extracellular and voltage-dependent effect. Xu, S.Z., Zeng, F., Boulay, G., Grimm, C., Harteneck, C., Beech, D.J. Br. J. Pharmacol. (2005)
- Desensitization of canonical transient receptor potential channel 5 by protein kinase C. Zhu, M.H., Chae, M., Kim, H.J., Lee, Y.M., Kim, M.J., Jin, N.G., Yang, D.K., So, I., Kim, K.W. Am. J. Physiol., Cell Physiol. (2005)
- TRPC1 functions as a store-operated Ca2+ channel in intestinal epithelial cells and regulates early mucosal restitution after wounding. Rao, J.N., Platoshyn, O., Golovina, V.A., Liu, L., Zou, T., Marasa, B.S., Turner, D.J., Yuan, J.X., Wang, J.Y. Am. J. Physiol. Gastrointest. Liver Physiol. (2006)
- A cytosolic residue mediates Mg2+ block and regulates inward current amplitude of a transient receptor potential channel. Obukhov, A.G., Nowycky, M.C. J. Neurosci. (2005)
- Transient receptor potential protein subunit assembly and membrane distribution in human platelets. Brownlow, S.L., Sage, S.O. Thromb. Haemost. (2005)
- mRNA distribution analysis of human TRPC family in CNS and peripheral tissues. Riccio, A., Medhurst, A.D., Mattei, C., Kelsell, R.E., Calver, A.R., Randall, A.D., Benham, C.D., Pangalos, M.N. Brain Res. Mol. Brain Res. (2002)
- Calmodulin and calcium interplay in the modulation of TRPC5 channel activity. Identification of a novel C-terminal domain for calcium/calmodulin-mediated facilitation. Ordaz, B., Tang, J., Xiao, R., Salgado, A., Sampieri, A., Zhu, M.X., Vaca, L. J. Biol. Chem. (2005)
- E3-targeted anti-TRPC5 antibody inhibits store-operated calcium entry in freshly isolated pial arterioles. Xu, S.Z., Boulay, G., Flemming, R., Beech, D.J. Am. J. Physiol. Heart Circ. Physiol. (2006)
- Cellular localization of TRPC5 in the substantia nigra of rat. De March, Z., Giampà, C., Patassini, S., Bernardi, G., Fusco, F.R. Neurosci. Lett. (2006)
- Lanthanides potentiate TRPC5 currents by an action at extracellular sites close to the pore mouth. Jung, S., Mühle, A., Schaefer, M., Strotmann, R., Schultz, G., Plant, T.D. J. Biol. Chem. (2003)
- Calcium-sensing mechanism in TRPC5 channels contributing to retardation of neurite outgrowth. Hui, H., McHugh, D., Hannan, M., Zeng, F., Xu, S.Z., Khan, S.U., Levenson, R., Beech, D.J., Weiss, J.L. J. Physiol. (Lond.) (2006)
- Human TRPC5 channel activated by a multiplicity of signals in a single cell. Zeng, F., Xu, S.Z., Jackson, P.K., McHugh, D., Kumar, B., Fountain, S.J., Beech, D.J. J. Physiol. (Lond.) (2004)
- Bipolar phospholipid sensing by TRPC5 calcium channel. Beech, D.J. Biochem. Soc. Trans. (2007)
- Potentiation of TRPC5 by protons. Semtner, M., Schaefer, M., Pinkenburg, O., Plant, T.D. J. Biol. Chem. (2007)
- A functional link between store-operated and TRPC channels revealed by the 3,5-bis(trifluoromethyl)pyrazole derivative, BTP2. He, L.P., Hewavitharana, T., Soboloff, J., Spassova, M.A., Gill, D.L. J. Biol. Chem. (2005)
- A sphingosine-1-phosphate-activated calcium channel controlling vascular smooth muscle cell motility. Xu, S.Z., Muraki, K., Zeng, F., Li, J., Sukumar, P., Shah, S., Dedman, A.M., Flemming, P.K., McHugh, D., Naylor, J., Cheong, A., Bateson, A.N., Munsch, C.M., Porter, K.E., Beech, D.J. Circ. Res. (2006)
- Formation of novel TRPC channels by complex subunit interactions in embryonic brain. Strübing, C., Krapivinsky, G., Krapivinsky, L., Clapham, D.E. J. Biol. Chem. (2003)
- Association of immunophilins with mammalian TRPC channels. Sinkins, W.G., Goel, M., Estacion, M., Schilling, W.P. J. Biol. Chem. (2004)
- Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells. Sours, S., Du, J., Chu, S., Ding, M., Zhou, X.J., Ma, R. Am. J. Physiol. Renal Physiol. (2006)
- Ca2+-calmodulin-dependent myosin light chain kinase is essential for activation of TRPC5 channels expressed in HEK293 cells. Shimizu, S., Yoshida, T., Wakamori, M., Ishii, M., Okada, T., Takahashi, M., Seto, M., Sakurada, K., Kiuchi, Y., Mori, Y. J. Physiol. (Lond.) (2006)
- Molecular cloning and characterization of TRPC5 (HTRP5), the human homologue of a mouse brain receptor-activated capacitative Ca2+ entry channel. Sossey-Alaoui, K., Lyon, J.A., Jones, L., Abidi, F.E., Hartung, A.J., Hane, B., Schwartz, C.E., Stevenson, R.E., Srivastava, A.K. Genomics (1999)
- Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: stereospecific recognition within the active site of an enzyme and its consequences for the drug design. Temperini, C., Scozzafava, A., Vullo, D., Supuran, C.T. J. Med. Chem. (2006)