Gene Review:
KLF11 - Kruppel-like factor 11
Homo sapiens
Synonyms:
FKLF, FKLF1, Krueppel-like factor 11, MODY7, TGFB-inducible early growth response protein 2, ...
Florez,
Zhu,
Urrutia,
Winckler,
Pixley,
Harth,
Urrutia,
Buchholz,
Ersek,
Bengtsson Bostr??m,
Colón,
Daly,
Hirschhorn,
Narayan,
Ardlie,
Groop,
Saxena,
Adler,
Jungert,
Burtt,
Buck,
Campbell,
Almgren,
Puri,
Fernandez-Zapico,
Zanjani,
Shah,
Tuomi,
Altshuler,
Gaudet,
Jin,
Gress,
Cook,
Lerman,
Cao,
Ellenrieder,
- KLF11 mediates a critical mechanism in TGF-beta signaling that is inactivated by Erk-MAPK in pancreatic cancer cells. Ellenrieder, V., Buck, A., Harth, A., Jungert, K., Buchholz, M., Adler, G., Urrutia, R., Gress, T.M. Gastroenterology (2004)
- An mSin3A interaction domain links the transcriptional activity of KLF11 with its role in growth regulation. Fernandez-Zapico, M.E., Mladek, A., Ellenrieder, V., Folch-Puy, E., Miller, L., Urrutia, R. EMBO J. (2003)
- The effect of hypoxia and stem cell source on haemoglobin switching. Narayan, A.D., Ersek, A., Campbell, T.A., Colón, D.M., Pixley, J.S., Zanjani, E.D. Br. J. Haematol. (2005)
- Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. Neve, B., Fernandez-Zapico, M.E., Ashkenazi-Katalan, V., Dina, C., Hamid, Y.H., Joly, E., Vaillant, E., Benmezroua, Y., Durand, E., Bakaher, N., Delannoy, V., Vaxillaire, M., Cook, T., Dallinga-Thie, G.M., Jansen, H., Charles, M.A., Clément, K., Galan, P., Hercberg, S., Helbecque, N., Charpentier, G., Prentki, M., Hansen, T., Pedersen, O., Urrutia, R., Melloul, D., Froguel, P. Proc. Natl. Acad. Sci. U.S.A. (2005)
- KLF11-mediated repression antagonizes Sp1/sterol-responsive element-binding protein-induced transcriptional activation of caveolin-1 in response to cholesterol signaling. Cao, S., Fernandez-Zapico, M.E., Jin, D., Puri, V., Cook, T.A., Lerman, L.O., Zhu, X.Y., Urrutia, R., Shah, V. J. Biol. Chem. (2005)
- Molecular cloning and characterization of TIEG2 reveals a new subfamily of transforming growth factor-beta-inducible Sp1-like zinc finger-encoding genes involved in the regulation of cell growth. Cook, T., Gebelein, B., Mesa, K., Mladek, A., Urrutia, R. J. Biol. Chem. (1998)
- FKLF, a novel Krüppel-like factor that activates human embryonic and fetal beta-like globin genes. Asano, H., Li, X.S., Stamatoyannopoulos, G. Mol. Cell. Biol. (1999)
- The Kruppel-Like Factor 11 (KLF11) Q62R Polymorphism Is Not Associated With Type 2 Diabetes in 8,676 People. Florez, J.C., Saxena, R., Winckler, W., Burtt, N.P., Almgren, P., Bengtsson Bostr??m, K., Tuomi, T., Gaudet, D., Ardlie, K.G., Daly, M.J., Altshuler, D., Hirschhorn, J.N., Groop, L. Diabetes (2006)
- Association analysis of Krüppel-like factor 11 variants with type 2 diabetes in Pima Indians. Ma, L., Hanson, R.L., Que, L.N., Mack, J.L., Franks, P.W., Infante, A.M., Kobes, S., Bogardus, C., Baier, L.J. J. Clin. Endocrinol. Metab. (2008)
- Dual functions of transcription factors, transforming growth factor-beta-inducible early gene (TIEG)2 and Sp3, are mediated by CACCC element and Sp1 sites of human monoamine oxidase (MAO) B gene. Ou, X.M., Chen, K., Shih, J.C. J. Biol. Chem. (2004)
- Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue. Johnsen, S.A., Subramaniam, M., Monroe, D.G., Janknecht, R., Spelsberg, T.C. J. Biol. Chem. (2002)
- A conserved alpha-helical motif mediates the interaction of Sp1-like transcriptional repressors with the corepressor mSin3A. Zhang, J.S., Moncrieffe, M.C., Kaczynski, J., Ellenrieder, V., Prendergast, F.G., Urrutia, R. Mol. Cell. Biol. (2001)