Gene Review:
codA - cytosine deaminase
Escherichia coli O157:H7 str. EDL933
- Localization of the codA gene on the Escherichia coli chromosome. Austin, E.A., Huber, B.E. J. Bacteriol. (1993)
- Cloning, sequence analysis, and purification of choline oxidase from Arthrobacter globiformis: a bacterial enzyme involved in osmotic stress tolerance. Fan, F., Ghanem, M., Gadda, G. Arch. Biochem. Biophys. (2004)
- Cytosine deaminase/5-fluorocytosine-based vaccination against liver tumors: evidence of distant bystander effect. Pierrefite-Carle, V., Baqué, P., Gavelli, A., Mala, M., Chazal, M., Gugenheim, J., Bourgeon, A., Milano, G., Staccini, P., Rossi, B. J. Natl. Cancer Inst. (1999)
- Cytosine deaminase adenoviral vector and 5-fluorocytosine selectively reduce breast cancer cells 1 million-fold when they contaminate hematopoietic cells: a potential purging method for autologous transplantation. Garcia-Sanchez, F., Pizzorno, G., Fu, S.Q., Nanakorn, T., Krause, D.S., Liang, J., Adams, E., Leffert, J.J., Yin, L.H., Cooperberg, M.R., Hanania, E., Wang, W.L., Won, J.H., Peng, X.Y., Cote, R., Brown, R., Burtness, B., Giles, R., Crystal, R., Deisseroth, A.B. Blood (1998)
- Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. Aghi, M., Kramm, C.M., Chou, T.C., Breakefield, X.O., Chiocca, E.A. J. Natl. Cancer Inst. (1998)
- Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system. Mullen, C.A., Kilstrup, M., Blaese, R.M. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Genetic evidence for a repressor of synthesis of cytosine deaminase and purine biosynthesis enzymes in Escherichia coli. Kilstrup, M., Meng, L.M., Neuhard, J., Nygaard, P. J. Bacteriol. (1989)
- Pyrimidine, purine and nitrogen control of cytosine deaminase synthesis in Escherichia coli K 12. Involvement of the glnLG and purR genes in the regulation of codA expression. Andersen, L., Kilstrup, M., Neuhard, J. Arch. Microbiol. (1989)
- Concomitant expression of E. coli cytosine deaminase and uracil phosphoribosyltransferase improves the cytotoxicity of 5-fluorocytosine. Tiraby, M., Cazaux, C., Baron, M., Drocourt, D., Reynes, J.P., Tiraby, G. FEMS Microbiol. Lett. (1998)
- Killing Epstein-Barr virus-positive B lymphocytes by gene therapy: comparing the efficacy of cytosine deaminase and herpes simplex virus thymidine kinase. Rogers, R.P., Ge, J.Q., Holley-Guthrie, E., Hoganson, D.K., Comstock, K.E., Olsen, J.C., Kenney, S. Hum. Gene Ther. (1996)
- Provision of positive and negative selections in retroviral vectors containing the cytosine deaminase gene. Shiau, A.L., Yang, H.M., Wu, P., Wu, C.L. Gene Ther. (1998)
- Cytosine deaminase as a negative selective marker for Arabidopsis. Perera, R.J., Linard, C.G., Signer, E.R. Plant Mol. Biol. (1993)
- Characterization of the Escherichia coli codBA operon encoding cytosine permease and cytosine deaminase. Danielsen, S., Kilstrup, M., Barilla, K., Jochimsen, B., Neuhard, J. Mol. Microbiol. (1992)
- Adenoviral-mediated transfer of a heat-inducible double suicide gene into prostate carcinoma cells. Blackburn, R.V., Galoforo, S.S., Corry, P.M., Lee, Y.J. Cancer Res. (1998)
- In vivo selective gene expression and therapy mediated by adenoviral vectors for human carcinoembryonic antigen-producing gastric carcinoma. Lan, K.H., Kanai, F., Shiratori, Y., Ohashi, M., Tanaka, T., Okudaira, T., Yoshida, Y., Hamada, H., Omata, M. Cancer Res. (1997)
- Low-Dose Etoposide Enhances Telomerase-Dependent Adenovirus-Mediated Cytosine Deaminase Gene Therapy through Augmentation of Adenoviral Infection and Transgene Expression in a Syngeneic Bladder Tumor Model. Shieh, G.S., Shiau, A.L., Yo, Y.T., Lin, P.R., Chang, C.C., Tzai, T.S., Wu, C.L. Cancer Res. (2006)
- Host responses and persistence of vector genome following intrabronchial administration of an E1(-)E3(-) adenovirus gene transfer vector to normal individuals. Harvey, B.G., Hackett, N.R., Ely, S., Crystal, R.G. Mol. Ther. (2001)
- Improved herpes simplex virus type 1 amplicon vectors for proportional coexpression of positron emission tomography marker and therapeutic genes. Jacobs, A.H., Winkeler, A., Hartung, M., Slack, M., Dittmar, C., Kummer, C., Knoess, C., Galldiks, N., Vollmar, S., Wienhard, K., Heiss, W.D. Hum. Gene Ther. (2003)
- In vivo adenovirus-mediated gene transfer of the Escherichia coli cytosine deaminase gene to human colon carcinoma-derived tumors induces chemosensitivity to 5-fluorocytosine. Hirschowitz, E.A., Ohwada, A., Pascal, W.R., Russi, T.J., Crystal, R.G. Hum. Gene Ther. (1995)
- Transduction of cytosine deaminase gene makes rat glioma cells highly sensitive to 5-fluorocytosine. Ge, K., Xu, L., Zheng, Z., Xu, D., Sun, L., Liu, X. Int. J. Cancer (1997)
- Alanine-scanning mutagenesis reveals a cytosine deaminase mutant with altered substrate preference. Mahan, S.D., Ireton, G.C., Stoddard, B.L., Black, M.E. Biochemistry (2004)
- Genetic prodrug activation therapy for breast cancer: A phase I clinical trial of erbB-2-directed suicide gene expression. Pandha, H.S., Martin, L.A., Rigg, A., Hurst, H.C., Stamp, G.W., Sikora, K., Lemoine, N.R. J. Clin. Oncol. (1999)
- Regional versus systemic delivery of recombinant vaccinia virus as suicide gene therapy for murine liver metastases. Gnant, M.F., Puhlmann, M., Bartlett, D.L., Alexander, H.R. Ann. Surg. (1999)