MeSH Review:
Bystander Effect
Cummins,
Bunn,
Hall,
Donze,
Mestecky,
Jackson,
Drake,
Wilbert,
Hinds,
Gilbert,
Pierrefite-Carle,
Baqué,
Gavelli,
Mala,
Chazal,
Gugenheim,
Bourgeon,
Milano,
Staccini,
Rossi,
Djeha,
Hulme,
Dexter,
Mountain,
Young,
Searle,
Kerr,
Wrighton,
Mesnil,
Piccoli,
Yamasaki,
Wilson,
Pullen,
Hogg,
Helsby,
Hicks,
Denny,
Dhib-Jalbut,
Chen,
Said,
Zhan,
Johnson,
Martin,
Robe,
Princen,
Martin,
Malgrange,
Stevenaert,
Moonen,
Gielen,
Merville,
Bours,
- Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway. Homann, D., Holz, A., Bot, A., Coon, B., Wolfe, T., Petersen, J., Dyrberg, T.P., Grusby, M.J., von Herrath, M.G. Immunity (1999)
- Suicide gene therapy for plasma cell tumors. Dilber, M.S., Abedi, M.R., Björkstrand, B., Christensson, B., Gahrton, G., Xanthopoulos, K.G., Smith, C.I. Blood (1996)
- Quantitation of bystander effects in nitroreductase suicide gene therapy using three-dimensional cell cultures. Wilson, W.R., Pullen, S.M., Hogg, A., Helsby, N.A., Hicks, K.O., Denny, W.A. Cancer Res. (2002)
- A tumor suppressor gene, Cx26, also mediates the bystander effect in HeLa cells. Mesnil, M., Piccoli, C., Yamasaki, H. Cancer Res. (1997)
- Rudimentary TCR signaling triggers default IL-10 secretion by human Th1 cells. Burrows, G.G., Chou, Y.K., Wang, C., Chang, J.W., Finn, T.P., Culbertson, N.E., Kim, J., Bourdette, D.N., Lewinsohn, D.A., Lewinsohn, D.M., Ikeda, M., Yoshioka, T., Allen, C.N., Offner, H., Vandenbark, A.A. J. Immunol. (2001)
- Recycling of vitamin C by a bystander effect. Nualart, F.J., Rivas, C.I., Montecinos, V.P., Godoy, A.S., Guaiquil, V.H., Golde, D.W., Vera, J.C. J. Biol. Chem. (2003)
- Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens. Weiner, H.L., Friedman, A., Miller, A., Khoury, S.J., al-Sabbagh, A., Santos, L., Sayegh, M., Nussenblatt, R.B., Trentham, D.E., Hafler, D.A. Annu. Rev. Immunol. (1994)
- Induction of mucosal tolerance in Peyer's patch-deficient, ligated small bowel loops. Kraus, T.A., Brimnes, J., Muong, C., Liu, J.H., Moran, T.M., Tappenden, K.A., Boros, P., Mayer, L. J. Clin. Invest. (2005)
- Re: Cytosine deaminase/5-fluorocytosine-based vaccination against liver tumors: evidence of distant bystander effect. Pierrefite-Carle, V., Gavelli, A., Brossette, N., Baqué, P., Benchimol, D., Bourgeon, A., Staccini, P., Rossi, B. J. Natl. Cancer Inst. (2000)
- Cytosine deaminase/5-fluorocytosine-based vaccination against liver tumors: evidence of distant bystander effect. Pierrefite-Carle, V., Baqué, P., Gavelli, A., Mala, M., Chazal, M., Gugenheim, J., Bourgeon, A., Milano, G., Staccini, P., Rossi, B. J. Natl. Cancer Inst. (1999)
- Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo. Aghi, M., Kramm, C.M., Breakefield, X.O. J. Natl. Cancer Inst. (1999)
- In vitro and in vivo effects of retrovirus-mediated transfer of the connexin 43 gene in malignant gliomas: consequences for HSVtk/GCV anticancer gene therapy. Cirenei, N., Colombo, B.M., Mesnil, M., Benedetti, S., Yamasaki, H., Finocchiaro, G. Gene Ther. (1998)
- Bystander effects of cancer cell lines transduced with the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster and synergistic enhancement by hydroxyurea. Zheng, X., Johansson, M., Karlsson, A. Mol. Pharmacol. (2001)
- Pharmacological modulation of the bystander effect in the herpes simplex virus thymidine kinase/ganciclovir gene therapy system: effects of dibutyryl adenosine 3',5'-cyclic monophosphate, alpha-glycyrrhetinic acid, and cytosine arabinoside. Robe, P.A., Princen, F., Martin, D., Malgrange, B., Stevenaert, A., Moonen, G., Gielen, J., Merville, M., Bours, V. Biochem. Pharmacol. (2000)
- Glatiramer acetate-reactive peripheral blood mononuclear cells respond to multiple myelin antigens with a Th2-biased phenotype. Dhib-Jalbut, S., Chen, M., Said, A., Zhan, M., Johnson, K.P., Martin, R. J. Neuroimmunol. (2003)
- In vitro exposure to highly cytopathic HIV-1 X4 strains increases expression of mucosa-associated integrins on CD4(+) T cells. Cummins, J.E., Bunn, W.J., Hall, S.D., Donze, H.H., Mestecky, J., Jackson, S. Virology (2001)
- The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified. Freeman, S.M., Abboud, C.N., Whartenby, K.A., Packman, C.H., Koeplin, D.S., Moolten, F.L., Abraham, G.N. Cancer Res. (1993)
- Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancer. Bouvet, M., Ellis, L.M., Nishizaki, M., Fujiwara, T., Liu, W., Bucana, C.D., Fang, B., Lee, J.J., Roth, J.A. Cancer Res. (1998)
- Gap junctions: the "kiss of death" and the "kiss of life". Andrade-Rozental, A.F., Rozental, R., Hopperstad, M.G., Wu, J.K., Vrionis, F.D., Spray, D.C. Brain Res. Brain Res. Rev. (2000)
- HSV vector cytotoxicity is inversely correlated with effective TK/GCV suicide gene therapy of rat gliosarcoma. Moriuchi, S., Krisky, D.M., Marconi, P.C., Tamura, M., Shimizu, K., Yoshimine, T., Cohen, J.B., Glorioso, J.C. Gene Ther. (2000)
- Antitumor activity and bystander effect of adenovirally delivered tissue inhibitor of metalloproteinases-3. Ahonen, M., Ala-Aho, R., Baker, A.H., George, S.J., Grénman, R., Saarialho-Kere, U., Kähäri, V.M. Mol. Ther. (2002)
- Gap junctions promote the bystander effect of herpes simplex virus thymidine kinase in vivo. Dilber, M.S., Abedi, M.R., Christensson, B., Björkstrand, B., Kidder, G.M., Naus, C.C., Gahrton, G., Smith, C.I. Cancer Res. (1997)
- Essential requirement of I-A region-identical host bone marrow or bone marrow-derived cells for tumor neutralization by primed L3T4+ T cells. Ozawa, H., Iwaguchi, T., Kataoka, T. J. Immunol. (1987)
- Differential ganciclovir-mediated cell killing by glutamine 125 mutants of herpes simplex virus type 1 thymidine kinase. Drake, R.R., Wilbert, T.N., Hinds, T.A., Gilbert, K.M. J. Biol. Chem. (1999)
- Mechanism of radiation-induced bystander effect: role of the cyclooxygenase-2 signaling pathway. Zhou, H., Ivanov, V.N., Gillespie, J., Geard, C.R., Amundson, S.A., Brenner, D.J., Yu, Z., Lieberman, H.B., Hei, T.K. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Adenovirus vector-based purging of multiple myeloma cells. Teoh, G., Chen, L., Urashima, M., Tai, Y.T., Celi, L.A., Chen, D., Chauhan, D., Ogata, A., Finberg, R.W., Webb, I.J., Kufe, D.W., Anderson, K.C. Blood (1998)
- Ionizing radiation induces DNA double-strand breaks in bystander primary human fibroblasts. Sokolov, M.V., Smilenov, L.B., Hall, E.J., Panyutin, I.G., Bonner, W.M., Sedelnikova, O.A. Oncogene (2005)
- Factors underlying the cell growth-related bystander responses to alpha particles. Iyer, R., Lehnert, B.E., Svensson, R. Cancer Res. (2000)
- p53 and PTEN/MMAC1/TEP1 gene therapy of human prostate PC-3 carcinoma xenograft, using transferrin-facilitated lipofection gene delivery strategy. Seki, M., Iwakawa, J., Cheng, H., Cheng, P.W. Hum. Gene Ther. (2002)
- Characterization of the bystander effect of somatostatin receptor sst2 after in vivo gene transfer into human pancreatic cancer cells. Carrere, N., Vernejoul, F., Souque, A., Asnacios, A., Vaysse, N., Pradayrol, L., Susini, C., Buscail, L., Cordelier, P. Hum. Gene Ther. (2005)
- Gene therapy for pancreatic carcinoma: local and distant antitumor effects after somatostatin receptor sst2 gene transfer. Rochaix, P., Delesque, N., Estève, J.P., Saint-Laurent, N., Voight, J.J., Vaysse, N., Susini, C., Buscail, L. Hum. Gene Ther. (1999)
- Cyclophosphamide induces type I interferon and augments the number of CD44(hi) T lymphocytes in mice: implications for strategies of chemoimmunotherapy of cancer. Schiavoni, G., Mattei, F., Di Pucchio, T., Santini, S.M., Bracci, L., Belardelli, F., Proietti, E. Blood (2000)
- Bystander effect in herpes simplex virus-thymidine kinase/ganciclovir cancer gene therapy: role of gap-junctional intercellular communication. Mesnil, M., Yamasaki, H. Cancer Res. (2000)
- Contribution of CD95 ligand-induced neutrophil infiltration to the bystander effect in p53 gene therapy for human cancer. Waku, T., Fujiwara, T., Shao, J., Itoshima, T., Murakami, T., Kataoka, M., Gomi, S., Roth, J.A., Tanaka, N. J. Immunol. (2000)
- Gene therapy against an experimental glioma using adeno-associated virus vectors. Okada, H., Miyamura, K., Itoh, T., Hagiwara, M., Wakabayashi, T., Mizuno, M., Colosi, P., Kurtzman, G., Yoshida, J. Gene Ther. (1996)
- Expression of Escherichia coli B nitroreductase in established human tumor xenografts in mice results in potent antitumoral and bystander effects upon systemic administration of the prodrug CB1954. Djeha, A.H., Hulme, A., Dexter, M.T., Mountain, A., Young, L.S., Searle, P.F., Kerr, D.J., Wrighton, C.J. Cancer Gene Ther. (2000)