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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Food Supply

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Disease relevance of Food Supply


Psychiatry related information on Food Supply


High impact information on Food Supply

  • Numbers of adults breeding probably reflect food supplies and recruitment from more successful colonies to the south, but improving fledging rates (up to 0.9 young per nest in 1974) reflect better egg survival and improving eggshell condition, with declining DDE contamination in anchovies, their major food source [8].
  • CONCLUSIONS: A 19% reduction in NTD birth prevalence occurred following folic acid fortification of the US food supply [1].
  • A cross section of the population of Michigan was studied in 1978 to evaluate residual burdens of polybrominated biphenyls (PBBs), a flame-retardant chemical that had contaminated the state's food supply five years earlier [9].
  • Wheat (Triticum aestivum L.), rice (Oryza sativa L.), and maize (Zea mays L.) provide about two-thirds of all energy in human diets, and four major cropping systems in which these cereals are grown represent the foundation of human food supply [10].
  • The higher rate of NPY release in fasted rats returned to the control range after 24 h of ad libitum food supply [11].

Biological context of Food Supply

  • This article uses folic acid as an example to illustrate some of the complex issues and general principles that emerge when evaluating fortification of the food supply as one possible means to address a public health recommendation [12].
  • As flavonoids affect cell signalling and DNA replication, and because the flavonoid content of the human food supply is being increased, determining the effects of flavonoids on meiotic fidelity is important [13].
  • Accustomed to a warm climate and a constant and predictable food supply, bacteria exposed to luminal nutrient starvation and a catabolically stressed host may express virulence determinants that can harm the host [14].
  • Inasmuch as cadmium in the U.S. food supply affords an estimated safety factor of only 4- to 15-fold, it is important to establish factors that affect the bioavailability of cadmium from foods [15].

Anatomical context of Food Supply


Associations of Food Supply with chemical compounds

  • Data are limited on circulating folate concentrations in pregnant African American women after folic acid fortification of the food supply was implemented [5].
  • On the basis of currently available information, there is little basis for recommending increased or decreased use of fructose in the general food supply or in products for special dietary use [17].
  • We found evidence that the concentrations of plasma corticosterone in chicks were higher under poor food supply in dense, young forests than in sparse, old forests [18].
  • BACKGROUND: Accidental contamination with polybrominated biphenyls (PBBs) of the Michigan food supply in 1973 led to the exposure of more than 4000 individuals and to formation of the PBB cohort registry (1976-1979) [19].
  • Resveratrol is a prototype of a plethora of bioactive polyphenols in the food supply that has just begun to be mined for cancer preventive agents [20].

Gene context of Food Supply

  • The Ministry of Agriculture, Fisheries and Food (MAFF) has the responsibility for safeguarding the food supply from authorised and accidental releases of radioactivity to the environment [21].
  • Because the American food supply is now being fortified with folic acid, concern is increasing about neurologic exacerbation in individuals with marginal vitamin B12 status and high-dose folate intake [22].
  • Our data suggest that iodinization of the food supply is not associated with adverse trends in the occurrence of thyroid cancer [23].
  • Its appearance was likely caused by changes in the rendering process used to produce a meat and bone supplement for cattle, changes that allowed this prion to enter the bovine food supply [24].
  • Ongoing levels of human exposure to BSE infectivity were also estimated, together with the effect on these of a range of possible exposure-reduction strategies that might replace the current rule banning tissue from cattle over 30 months (OTM) of age from the human food supply [25].


  1. Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects. Honein, M.A., Paulozzi, L.J., Mathews, T.J., Erickson, J.D., Wong, L.Y. JAMA (2001) [Pubmed]
  2. Effectiveness of food fortification in the United States: the case of pellagra. Park, Y.K., Sempos, C.T., Barton, C.N., Vanderveen, J.E., Yetley, E.A. American journal of public health. (2000) [Pubmed]
  3. Effect of sodium nitrite, carbon monoxide, and reduced food supply on unilateral ovarian compensatory hypertrophy in the rat. Matthies, E., Pankow, D., Ponsold, W. Toxicol. Appl. Pharmacol. (1978) [Pubmed]
  4. Effect of restricted food supply to pregnant rats inhaling carbon monoxide on fetal weight, compared with cigarette smoke exposure. Tachi, N., Aoyama, M. Bulletin of environmental contamination and toxicology. (1986) [Pubmed]
  5. Status of plasma folate after folic acid fortification of the food supply in pregnant African American women and the influences of diet, smoking, and alcohol consumption. Stark, K.D., Pawlosky, R.J., Beblo, S., Murthy, M., Flanagan, V.P., Janisse, J., Buda-Abela, M., Rockett, H., Whitty, J.E., Sokol, R.J., Hannigan, J.H., Salem, N. Am. J. Clin. Nutr. (2005) [Pubmed]
  6. Chronic exposure to cadmium attenuates behavioral sensitization to morphine. Nation, J.R., Miller, D.K., Livermore, C.L. Psychopharmacology (Berl.) (1997) [Pubmed]
  7. Intraperitoneal administration of recombinant human interleukin-1 beta inhibits osmotic thirst in the rat. Osaka, T., Kannan, H., Kawano, S., Ueta, Y., Yamashita, H. Physiol. Behav. (1992) [Pubmed]
  8. Brown pelicans: improved reproduction off the southern California coast. Anderson, D.W., Jehl, J.R., Risebrough, R.W., Woods, L.A., Deweese, L.R., Edgecomb, W.G. Science (1975) [Pubmed]
  9. Human tissue burdens of halogenated aromatic chemicals in Michigan. Wolff, M.S., Anderson, H.A., Selikoff, I.J. JAMA (1982) [Pubmed]
  10. Ecological intensification of cereal production systems: yield potential, soil quality, and precision agriculture. Cassman, K.G. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  11. Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food. Kalra, S.P., Dube, M.G., Sahu, A., Phelps, C.P., Kalra, P.S. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  12. Evaluating food fortification options: general principles revisited with folic acid. Crane, N.T., Wilson, D.B., Cook, D.A., Lewis, C.J., Yetley, E.A., Rader, J.I. American journal of public health. (1995) [Pubmed]
  13. Unaltered meiotic chromosome segregation in Drosophila melanogaster raised on a 5% quercetin diet. Schramm, D.D., Collins, H.E., Hawley, R.S., German, J.B. Food Chem. Toxicol. (1998) [Pubmed]
  14. Effect of immunonutrition on virulence strategies in bacteria. Alverdy, J., Stern, E. Nutrition (Burbank, Los Angeles County, Calif.) (1998) [Pubmed]
  15. Cadmium bioavailability. Fox, M.R. Fed. Proc. (1983) [Pubmed]
  16. Independent modulation by food supply of two distinct sodium-activated D-glucose transport systems in the guinea pig jejunal brush-border membrane. Brot-Laroche, E., Dao, M.T., Alcalde, A.I., Delhomme, B., Triadou, N., Alvarado, F. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  17. The public health significance of dietary fructose. Glinsmann, W.H., Bowman, B.A. Am. J. Clin. Nutr. (1993) [Pubmed]
  18. Forest management is associated with physiological stress in an old-growth forest passerine. Suorsa, P., Huhta, E., Nikula, A., Nikinmaa, M., Jäntti, A., Helle, H., Hakkarainen, H. Proc. Biol. Sci. (2003) [Pubmed]
  19. Growth in girls exposed in utero and postnatally to polybrominated biphenyls and polychlorinated biphenyls. Blanck, H.M., Marcus, M., Rubin, C., Tolbert, P.E., Hertzberg, V.S., Henderson, A.K., Zhang, R.H. Epidemiology (Cambridge, Mass.) (2002) [Pubmed]
  20. Resveratrol: a candidate nutritional substance for prostate cancer prevention. Stewart, J.R., Artime, M.C., O'Brian, C.A. J. Nutr. (2003) [Pubmed]
  21. The determination of low levels of radiocaesium and radioruthenium in foodstuffs. Carpenter, R.C., Sanders, T.W., Vernon, L.M., Toole, J., Morrison, R.T., Alderson, S.P. Sci. Total Environ. (1995) [Pubmed]
  22. Vitamin B12 deficiency in the elderly. Baik, H.W., Russell, R.M. Annu. Rev. Nutr. (1999) [Pubmed]
  23. Iodine supplementation in Sweden and regional trends in thyroid cancer incidence by histopathologic type. Pettersson, B., Coleman, M.P., Ron, E., Adami, H.O. Int. J. Cancer (1996) [Pubmed]
  24. Clinical implications of bovine spongiform encephalopathy. MacKnight, C. Clin. Infect. Dis. (2001) [Pubmed]
  25. Assessment of the risk posed by bovine spongiform encephalopathy in cattle in Great Britain and the impact of potential changes to current control measures. Ferguson, N.M., Donnelly, C.A. Proc. Biol. Sci. (2003) [Pubmed]
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