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MeSH Review

Anemia, Megaloblastic

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  1. Homocystinuria and megaloblastic anemia responsive to vitamin B12 therapy. An inborn error of metabolism due to a defect in cobalamin metabolism. Schuh, S., Rosenblatt, D.S., Cooper, B.A., Schroeder, M.L., Bishop, A.J., Seargeant, L.E., Haworth, J.C. N. Engl. J. Med. (1984) [Pubmed]
  2. Localization of the gene for thiamine-responsive megaloblastic anemia syndrome, on the long arm of chromosome 1, by homozygosity mapping. Neufeld, E.J., Mandel, H., Raz, T., Szargel, R., Yandava, C.N., Stagg, A., Fauré, S., Barrett, T., Buist, N., Cohen, N. Am. J. Hum. Genet. (1997) [Pubmed]
  3. Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria. Leclerc, D., Wilson, A., Dumas, R., Gafuik, C., Song, D., Watkins, D., Heng, H.H., Rommens, J.M., Scherer, S.W., Rosenblatt, D.S., Gravel, R.A. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  4. Circulating antibody to transcobalamin II causing retention of vitamin B12 in the blood. Carmel, R., Tatsis, B., Baril, L. Blood (1977) [Pubmed]
  5. Ineffective hematopoiesis in folate-deficient mice. Bills, N.D., Koury, M.J., Clifford, A.J., Dessypris, E.N. Blood (1992) [Pubmed]
  6. Intestinal absorption, liver uptake, and excretion of 3H-folic acid in folic acid-deficient, alcohol-consuming nonhuman primates. Blocker, D.E., Thenen, S.W. Am. J. Clin. Nutr. (1987) [Pubmed]
  7. The molecular basis of glutamate formiminotransferase deficiency. Hilton, J.F., Christensen, K.E., Watkins, D., Raby, B.A., Renaud, Y., de la Luna, S., Estivill, X., MacKenzie, R.E., Hudson, T.J., Rosenblatt, D.S. Hum. Mutat. (2003) [Pubmed]
  8. Bilateral retinal hemorrhages from megaloblastic anemia: case report and review of literature. Lam, S., Lam, B.L. Annals of ophthalmology. (1992) [Pubmed]
  9. Amnionless, essential for mouse gastrulation, is mutated in recessive hereditary megaloblastic anemia. Tanner, S.M., Aminoff, M., Wright, F.A., Liyanarachchi, S., Kuronen, M., Saarinen, A., Massika, O., Mandel, H., Broch, H., de la Chapelle, A. Nat. Genet. (2003) [Pubmed]
  10. Uracil in DNA in megaloblastic anemia. Luzzatto, L., Falusi, A.O., Joju, E.A. N. Engl. J. Med. (1981) [Pubmed]
  11. Studies of a patient with megaloblastic anemia and an abnormal transcobalamin II. Seligman, P.A., Steiner, L.L., Allen, R.H. N. Engl. J. Med. (1980) [Pubmed]
  12. Dihydrofolate reductase deficiency causing megaloblastic anemia in two families. Tauro, G.P., Danks, D.M., Rowe, P.B., Van der Weyden, M.B., Schwarz, M.A., Collins, V.L., Neal, B.W. N. Engl. J. Med. (1976) [Pubmed]
  13. The deoxyuridine suppression test identifies subtle cobalamin deficiency in patients without typical megaloblastic anemia. Carmel, R., Karnaze, D.S. JAMA (1985) [Pubmed]
  14. Cobalamin malabsorption in three siblings due to an abnormal intrinsic factor that is markedly susceptible to acid and proteolysis. Yang, Y.M., Ducos, R., Rosenberg, A.J., Catrou, P.G., Levine, J.S., Podell, E.R., Allen, R.H. J. Clin. Invest. (1985) [Pubmed]
  15. Cobalamin inactivation decreases purine and methionine synthesis in cultured lymphoblasts. Boss, G.R. J. Clin. Invest. (1985) [Pubmed]
  16. Acute megaloblastic anemia induced by high-dose trimethoprim-sulfamethoxazole. Kobrinsky, N.L., Ramsay, N.K. Ann. Intern. Med. (1981) [Pubmed]
  17. Severe megaloblastic anemia complicating pyrimethamine therapy. Chute, J.P., Decker, C.F., Cotelingam, J. Ann. Intern. Med. (1995) [Pubmed]
  18. Apoptosis in megaloblastic anemia occurs during DNA synthesis by a p53-independent, nucleoside-reversible mechanism. Koury, M.J., Price, J.O., Hicks, G.G. Blood (2000) [Pubmed]
  19. Neutrophil myeloperoxidase measurement uncovers masked megaloblastic anemia. Gulley, M.L., Bentley, S.A., Ross, D.W. Blood (1990) [Pubmed]
  20. Defective RNA ribose synthesis in fibroblasts from patients with thiamine-responsive megaloblastic anemia (TRMA). Boros, L.G., Steinkamp, M.P., Fleming, J.C., Lee, W.N., Cascante, M., Neufeld, E.J. Blood (2003) [Pubmed]
  21. Depressed cell-mediated immunity in megaloblastic anemia due to folic acid deficiency. Gross, R.L., Reid, J.V., Newberne, P.M., Burgess, B., Marston, R., Hift, W. Am. J. Clin. Nutr. (1975) [Pubmed]
  22. Male infertility due to germ cell apoptosis in mice lacking the thiamin carrier, Tht1. A new insight into the critical role of thiamin in spermatogenesis. Oishi, K., Barchi, M., Au, A.C., Gelb, B.D., Diaz, G.A. Dev. Biol. (2004) [Pubmed]
  23. Abnormal erythrocyte membrane protein pattern in severe megaloblastic anemia. Ballas, S.K. J. Clin. Invest. (1978) [Pubmed]
  24. Bone marrow cells from vitamin B12- and folate-deficient patients misincorporate uracil into DNA. Wickramasinghe, S.N., Fida, S. Blood (1994) [Pubmed]
  25. Cobalamin-dependent methionine synthase. Banerjee, R.V., Matthews, R.G. FASEB J. (1990) [Pubmed]
  26. Reversal of severe neurological abnormalities after vitamin B12 replacement in the Imerslund-Grasbeck syndrome. Salameh, M.M., Banda, R.W., Mohdi, A.A. J. Neurol. (1991) [Pubmed]
  27. Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules. Strope, S., Rivi, R., Metzger, T., Manova, K., Lacy, E. Development (2004) [Pubmed]
  28. The spectrum of mutations, including four novel ones, in the thiamine-responsive megaloblastic anemia gene SLC19A2 of eight families. Raz, T., Labay, V., Baron, D., Szargel, R., Anbinder, Y., Barrett, T., Rabl, W., Viana, M.B., Mandel, H., Baruchel, A., Cayuela, J.M., Cohen, N. Hum. Mutat. (2000) [Pubmed]
  29. The cloning and characterization of the human transcobalamin II gene. Regec, A., Quadros, E.V., Platica, O., Rothenberg, S.P. Blood (1995) [Pubmed]
  30. Defective gene expression, S phase progression, and maturation during hematopoiesis in E2F1/E2F2 mutant mice. Li, F.X., Zhu, J.W., Hogan, C.J., DeGregori, J. Mol. Cell. Biol. (2003) [Pubmed]
  31. Homozygous AMN mutation in hereditary selective intestinal malabsorption of vitamin B12 in Jordan. Al-Alami, J.R., Tanner, S.M., Tayeh, M.K., de la Chapelle, A., El-Shanti, H. Saudi medical journal. (2005) [Pubmed]
  32. Nucleic acid composition of bone marrow mononuclear cells in cobalamin deficiency. Ramsahoye, B.H., Burnett, A.K., Taylor, C. Blood (1996) [Pubmed]
  33. Folate measurements in patients on regular hemodialysis treatment. Bamonti-Catena, F., Buccianti, G., Porcella, A., Valenti, G., Como, G., Finazzi, S., Maiolo, A.T. Am. J. Kidney Dis. (1999) [Pubmed]
  34. Plasma cells with inclusions containing iron. Shanmugathasa, M., Sobel, H.J., Marquet, E., Trubowitz, S. Arch. Pathol. Lab. Med. (1979) [Pubmed]
  35. Megaloblastic anemia in an infant receiving total parenteral nutrition. Kaneko, K., Shimizu, T., Nagaoka, R., Fujiwara, S., Igarashi, J., Ohtomo, Y., Yamashiro, Y. Pediatrics international : official journal of the Japan Pediatric Society. (2002) [Pubmed]
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