Disease relevance of Ventriculostomy

• Patients who had undergone external ventriculostomies for noninflammatory occlusive hydrocephalus received either cefotaxime (2 g/30 min) or ceftriaxone (2 g/30 min) to treat extracerebral infections [1].
• Resumption of luteinizing hormone pulsatility and hypogonadotropic hypogonadism after endoscopic ventriculocisternostomy in a hydrocephalic patient [2].
• After recording the effects of diltiazem-induced hypotension during normal ICP, ICP was elevated by infusion through a ventriculostomy cannula of pH-adjusted Ringer's lactate, baselines were reestablished, and MAP was again reduced by 40 +/- 1% with diltiazem [3].

Psychiatry related information on Ventriculostomy

• The indications, contra-indications and complications concerning intracranial tumours, the hypophysis, combined open stereotactic procedures, third ventriculostomy, diseases of the extrapyramidal motor system, pain, epilepsy, psychosurgery and the transplantation of embryonal cells are discussed [4].

High impact information on Ventriculostomy

• METHODS: Patients with spontaneous supratentorial ICH were identified in our prospectively collected database to determine the following: age, sex, race, past medical history; Glasgow Coma Scale (GCS) score and blood pressure on admission; use of mechanical ventilation, mannitol, and ventriculostomy; and medical complications [5].
• Disposition and elimination of meropenem in cerebrospinal fluid of hydrocephalic patients with external ventriculostomy [6].
• Cerebrospinal fluid penetration of moxalactam in ventriculostomy patients [7].
• After a single 40-mg/kg dose to each of five infants with ventriculostomies, mean CSF levels of cefotaxime were 6.4, 5.7, and 4.5 micrograms/ml at 2, 4, and 6 h, respectively [8].
• The objective was to study the relation between changes in cerebral ventricular size and clinical outcome after neuroendoscopic third ventriculostomy (NTV) in both primary (no previous surgery) and secondary (previous CSF diversion for hydrocephalus) NTV [9].

Chemical compound and disease context of Ventriculostomy

• Nine patients with external ventriculostomy and suffering from hydrocephalus, due to non-inflammatory central nervous system diseases, were given ciprofloxacin (200 mg twice daily iv) [10].
• In 7 patients with an external ventriculostomy for occlusive hydrocephalus, each of whom was given 500 ml of a 10% solution IV over 4 h, serum and CSF were repeatedly sampled during and after the infusion and glycerol was measured enzymatically [11].

Biological context of Ventriculostomy

• CNS infections following clean neurosurgery are uncommon but occur with increased frequency following neurotrauma and placement of CSF shunts and ventriculostomies [12].
• In 11 neurosurgical patients (seven women, four men, aged 22-73 years) undergoing external ventriculostomy, serum and cerebrospinal fluid (CSF) pharmacokinetics of ceftazidime (CAZ) administered as a chemoprophylactic agent were evaluated [13].
• Problems were secondary wound healing after prolonged periods with ventriculostomy in place and rapid CSF-infection in cases of loosened screws which were not instantly removed [14].
• After endoscopic III ventriculostomy in the obstructive hydrocephalus group we noted increased CSF flow velocity with markedly increased stroke volume at the prepontine cistern [15].

Anatomical context of Ventriculostomy

• The patient underwent endoscopic fenestration of the quadrigeminal cistern arachnoid cyst and third ventriculostomy via one burr hole placed at the coronal suture [16].
• We conclude that the presence of a CSF flow void in the anterior/inferior third ventricle on a postoperative MR examination is sufficient to document patency of a third ventriculostomy [17].

Associations of Ventriculostomy with chemical compounds

• When ratios of simultaneously drawn ventriculostomy to serum moxalactam levels of 1, 2, 3, and 4 h were examined, the penetration ratios were 7.8 +/- 2.4, 11.2 +/- 1.3, 14.2 +/- 2.5, and 15.0 +/- 4.9%, respectively [7].
• Serial, simultaneous cerebrospinal fluid and plasma ceftriaxone levels were also determined in three additional patients with ventriculo-peritoneal shunt infections and external ventriculostomy drainage [18].
• Monitored variables were mean arterial blood pressure, ICP (ventriculostomy), end-tidal (ET) CO2, ET volatile anesthetic, the electroencephalogram, temperature, and arterial blood gases [19].
• Results of trimethoprim-sulfamethoxazole prophylaxis in ventriculostomy and shunting procedures. A double-blind randomized trial [20].
• The patient was treated with ventriculostomy, induction of labor, postdelivery shunting, albendazole, and prednisone [21].

Gene context of Ventriculostomy

• The majority of infections were associated with indwelling ventriculostomy tubes or CSF fistulae in patients receiving antimicrobial therapy [22].
• Risk factors for CSF infection included duration of monitoring greater than 5 days (RR 4.0 (1.3-11.9)); presence of ventriculostomy (RR 3.4 (1.0-10.7)); CSF leak (RR 6.3 (1.5-27.4)); concurrent systemic infection (RR 3.4 (1.2-9.5)); or serial ICPM (RR 4.9 (1. 7-13.8)) [23].
• CISS imaging and T2-weighted imaging were equally useful for monitoring postoperative changes in the sizes of ventricles or cysts and the presence of flow voids after third ventriculostomies [24].
• The SAB is shown to be relatively inaccurate with a wide range of variance, while the SAC is demonstrated to be an accurate, reliable, and safe method of continuous ICP measurement and an acceptable alternative to ventriculostomy [25].
• All patients had Glasgow Coma Scale scores of 8 or lower at 6 hours postinjury and were initially treated with ventriculostomy [26].

Analytical, diagnostic and therapeutic context of Ventriculostomy

• One hundred fifty-eight patients with Glasgow Coma Scale (GCS) scores of 7 or lower were managed using vascular volume expansion, cerebrospinal fluid drainage via ventriculostomy, systemic vasopressors (phenylephrine or norepinephrine), and mannitol to maintain a minimum CPP of at least 70 mm Hg [27].
• To determine the restoration of CSF pulsation, we compared the CSF waveform at the ventriculostomy with the CSF waveform at the aqueduct in a healthy control group [28].
• In clinical trials, the comparison of FTC with subdural and ventriculostomy waveforms and pressures showed essentially no difference [29].

References