Disease relevance of Child Development

• Toxicity to bilirubin in neonates: infant development during first year in relation to maximum neonatal serum bilirubin concentration [1].
• We studied the effect of diabetic nephropathy on the course of pregnancy, perinatal outcome, and infant development and determined the influence of pregnancy on maternal hypertension and renal function [2].
• In a community-based study of 4,309 children with neurodevelopmental disabilities who were referred to the Institute for Child Development, Tel Aviv, Israel, 62 (1.4%) had macrocephaly (head circumference above the ninety-eighth percentile for age), of whom 42 (1%) had macrocephaly not associated with hydrocephalus [3].
• The neurodevelopmental and cognitive outcome of long-term Intrauterine Growth Restriction (IUGR) has been followed up from pregnancy to school age at the Tel Aviv Child Development Centre [4].

Psychiatry related information on Child Development

• Maternal cocaine use during pregnancy is associated with medical and life-style characteristics detrimental to fetal and infant development [5].
• The Bayley Scales of Infant Development were collected at 12 and 24 months, and the Stanford Binet Intelligence Test and the Achenbach Child Behavior Checklist were collected at 36 months of age [6].
• On one hand, it is unclear whether treatment of ADHD with amphetamine-like stimulant medications for extended periods of time during child development can carry negative consequences, as manifested by an increase in use of illicit drugs, higher incidence of mania, psychosis, or other manifestations of psychopathology [7].
• Furthermore, by holding to the Freudian theory of child development Anna Freud was forced to limit the scope of child analysis, while Klein's application of Freudian practice has led to new discoveries about the development of the infant psyche [8].
• The purpose of this study was to determine if the abuse of children was prevalent among middle-class professionals in India. Face-to-face interviews were conducted with a stratified random sample of 319 subjects, in three cities in India, to assess their attitudes toward child rearing and their expectations about child development [9].

High impact information on Child Development

• Methylmercury and neurodevelopment: reanalysis of the Seychelles Child Development Study outcomes at 66 months of age [10].
• Child development following exposure to tricyclic antidepressants or fluoxetine throughout fetal life: a prospective, controlled study [11].
• In order to improve the basis upon which to advise women with diabetic nephropathy about pregnancy, we studied the effect of diabetic nephropathy on the course of pregnancy, perinatal outcome, infant development and long-term outcome of the mothers [12].
• Maternal thyroid peroxidase antibodies during pregnancy: a marker of impaired child development [13]?
• Docosahexaenoic acid (DHA) is important for infant development [14].

Chemical compound and disease context of Child Development

• Hair tests greatly improve detection and thus can enhance evaluations of the effects of prenatal cocaine use on fetal and child development [15].
• The level of serum thyroxine during the first 2 years was positively correlated with the Mental Development Index at 2 years of age (Bayley Scales of Infant Development) and the Verbal IQ at 6 years of age (Wechsler Preschool and Primary Scale of Intelligence) [16].
• In view of the neurotoxic properties of these substances following developmental exposure, we initiated a study on infant development in this remote coastal population [17].
• This enables the evaluation of nocturnal 6SMT excretion as a prognostic and diagnostic factor for child development [18].
• Objective: To determine whether exposure to polychlorinated biphenyls (PCBs) or dichlorodiphenyl dichloroethene (DDE), either transplacentally or through breast feeding, affected scores on the Bayley Scales of Infant Development at 6 or 12 months of age [19].

Biological context of Child Development

• The objective of this study was to evaluate hippocampally based recognition memory and infant development in IDMs with suspected brain iron deficiency (BID; cord ferritin </=34 microg/L) compared with IDMs with sufficient brain iron stores (BIS; cord ferritin >34 microg/L) using event-related potentials (ERPs) [20].
• Limited evidence also suggests no adverse effects of the etonogestrel implant on lactation parameters or infant development among users enrolled 28 to 56 days postpartum and followed for 4 months [21].
• To assess whether hypothyroxinemia has specific effects on neurodevelopment in premature infants, thyroid hormone levels were determined at 2 weeks of life and 40 weeks postconceptional age (PCA), and infants were evaluated at 3 months corrected age using the Bayley Scales of Infant Development and Early Infancy Temperament Questionnaire [22].
• Risk factors for infant development are considered in three areas: infant temperament, postpartum depression, and prenatal cocaine exposure [23].
• Vision screening at 8 and 18 months. Steering Committee of Oxford Region Child Development Project [24].

Anatomical context of Child Development

• PATIENTS AND METHODS: Forty-seven children treated with SCT for malignant or nonmalignant disorders who had no previous cranial radiation therapy, no central nervous system tumors, and were aged birth to 16 years were administered the Bayley Scales of Infant Development or IQ test before SCT and an intelligence test 1 and 2 years after SCT [25].
• Docosahexaenoic acid (DHA), a 22-carbon long-chain polyunsaturated fatty acid of the omega-3 family, is a major structural component of neural membranes and is a particularly important nutrient during infant development [26].

Gene context of Child Development

• CONCLUSIONS: These findings provide additional evidence for the role of the dopamine D4 receptor in ADHD during the course of child development [27].
• These hepatic P450 CYPs come "on line" at different times during fetal and infant development, and each one is discussed in that temporal sequence [28].
• CONCLUSION: No impact of child development on TPMT activity could be evidenced, suggesting that TPMT activity is already mature at birth [29].
• MAIN OUTCOME MEASURES: The Mental Development Index from the Bayley Scales of Infant Development was the main outcome measure for T1 and T2 [30].
• The CDI General Development Developmental Quotient was compared with the Clinical Adaptive Test/Clinical Linguistic and Auditory Milestone Scale (CAT/CLAMS) and the Bayley Scales of Infant Development, 2nd Edition (BSID-II) [31].

Analytical, diagnostic and therapeutic context of Child Development

• Of all the children born, 12.2% (439/3618) in the ICSI group and 11.9% (207/1738) in the IVF group underwent a formal developmental assessment using the Bayley Scale of Infant Development (mental scale) by a paediatrician blinded to the type of treatment [32].
• Obstetric analgesia and infant outcome in monkeys: infant development after intrapartum exposure to meperidine or alfentanil [33].
• The predictive value of the Neonatal Neurological Examination (NNE) adapted from Prechtl (1977) and the Infant Motor Screen (IMS) from Nickel (1989) at 4 months was studied in severely jaundiced infants in Zimbabwe. Fifty infants were examined with the NNE, 41 with the IMS and 43 with the Bayley Scales of Infant Development (BSID) (Bayley 1969) [34].
• However, intervention studies with term infants that have attempted to improve the DHA supply of infant formula and hence infant development have not yielded consistent results [35].
• RESULTS: KAP scores of the intervention group were higher than the scores of the control group, suggesting that the prevention program helped mothers acquire greater knowledge and more appropriate attitudes and practices about child development [36].

References