Gene Review:
DLL1 - delta-like 1 (Drosophila)
Homo sapiens
Synonyms:
DELTA1, DL1, Delta, Delta-like protein 1, Delta1, ...
- The Notch pathway in ovarian carcinomas and adenomas. Hopfer, O., Zwahlen, D., Fey, M.F., Aebi, S. Br. J. Cancer (2005)
- A novel cell line derived from de novo acute myeloblastic leukaemia with trilineage myelodysplasia which proliferates in response to a Notch ligand, Delta-1 protein. Tohda, S., Sakano, S., Ohsawa, M., Murakami, N., Nara, N. Br. J. Haematol. (2002)
- Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloid leukemia cell lines. Murata-Ohsawa, M., Tohda, S., Nara, N. Int. J. Mol. Med. (2004)
- Delta-1 negatively regulates the transition from prehypertrophic to hypertrophic chondrocytes during cartilage formation. Crowe, R., Zikherman, J., Niswander, L. Development (1999)
- Identification of a protein kinase associated with the cytoplasmic domain of the p60 tumor necrosis factor receptor. Darnay, B.G., Reddy, S.A., Aggarwal, B.B. J. Biol. Chem. (1994)
- Sequence-specific DNA-binding dominated by dehydration. Lundbäck, T., Härd, T. Proc. Natl. Acad. Sci. U.S.A. (1996)
- The cholinergic REM sleep induction test with pilocarpine in mildly depressed patients and normal controls. Lauriello, J., Kenny, W.M., Sutton, L., Golshan, S., Ruiz, C., Kelsoe, J., Rapaport, M., Gillin, J.C. Biol. Psychiatry (1993)
- Interactions between hypoglycemia and sleep architecture in children with type 1 diabetes mellitus. Pillar, G., Schuscheim, G., Weiss, R., Malhotra, A., McCowen, K.C., Shlitner, A., Peled, N., Shehadeh, N. J. Pediatr. (2003)
- Rethinking the Psoriasis Area and Severity Index: the impact of area should be increased. Jacobson, C.C., Kimball, A.B. Br. J. Dermatol. (2004)
- Patterns of antischistosomal drug usage in Qalyubia Governorate of the Nile Delta. McNeeley, D.F., Habib, M.A., El Alamy, M.A., Cline, B.L. Am. J. Trop. Med. Hyg. (1982)
- Plant biomarkers in aerosols record isotopic discrimination of terrestrial photosynthesis. Conte, M.H., Weber, J.C. Nature (2002)
- Isolation of an HTLV-III-related retrovirus from macaques with simian AIDS and its possible origin in asymptomatic mangabeys. Murphey-Corb, M., Martin, L.N., Rangan, S.R., Baskin, G.B., Gormus, B.J., Wolf, R.H., Andes, W.A., West, M., Montelaro, R.C. Nature (1986)
- A T cell-specific transcriptional enhancer within the human T cell receptor delta locus. Redondo, J.M., Hata, S., Brocklehurst, C., Krangel, M.S. Science (1990)
- Modulation of developmental signals by endocytosis: different means and many ends. Piddini, E., Vincent, J.P. Curr. Opin. Cell Biol. (2003)
- Zidovudine resensitization and dual HIV-1 resistance to zidovudine and lamivudine in the delta lamivudine roll-over study. Masquelier, B., Descamps, D., Carrière, I., Ferchal, F., Collin, G., Denayrolles, M., Ruffault, A., Chanzy, B., Izopet, J., Buffet-Janvresse, C., Schmitt, M.P., Race, E., Fleury, H.J., Aboulker, J.P., Yeni, P., Brun-Vézinet, F. Antivir. Ther. (Lond.) (1999)
- Arsenic trioxide induces apoptosis in human T-cell leukemia virus type 1- and type 2-infected cells by a caspase-3-dependent mechanism involving Bcl-2 cleavage. Mahieux, R., Pise-Masison, C., Gessain, A., Brady, J.N., Olivier, R., Perret, E., Misteli, T., Nicot, C. Blood (2001)
- Insulin-like growth factor-I regulates glucose-induced mitochondrial depolarization and apoptosis in human neuroblastoma. Leinninger, G.M., Russell, J.W., van Golen, C.M., Berent, A., Feldman, E.L. Cell Death Differ. (2004)
- ACE inhibitors to prevent end-stage renal disease: when to start and why possibly never to stop: a post hoc analysis of the REIN trial results. Ramipril Efficacy in Nephropathy. Ruggenenti, P., Perna, A., Remuzzi, G. J. Am. Soc. Nephrol. (2001)
- Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 envelope glycoprotein gB induces the integrin-dependent focal adhesion kinase-Src-phosphatidylinositol 3-kinase-rho GTPase signal pathways and cytoskeletal rearrangements. Sharma-Walia, N., Naranatt, P.P., Krishnan, H.H., Zeng, L., Chandran, B. J. Virol. (2004)
- Delta-1 activation of notch-1 signaling results in HES-1 transactivation. Jarriault, S., Le Bail, O., Hirsinger, E., Pourquié, O., Logeat, F., Strong, C.F., Brou, C., Seidah, N.G., Isra l, A. Mol. Cell. Biol. (1998)
- Extrathymic generation of tumor-specific T cells from genetically engineered human hematopoietic stem cells via Notch signaling. Zhao, Y., Parkhurst, M.R., Zheng, Z., Cohen, C.J., Riley, J.P., Gattinoni, L., Restifo, N.P., Rosenberg, S.A., Morgan, R.A. Cancer Res. (2007)
- Altered Notch ligand expression in human liver disease: further evidence for a role of the Notch signaling pathway in hepatic neovascularization and biliary ductular defects. Nijjar, S.S., Wallace, L., Crosby, H.A., Hubscher, S.G., Strain, A.J. Am. J. Pathol. (2002)
- The Notch signaling pathway is related to neurovascular progression of pancreatic cancer. Büchler, P., Gazdhar, A., Schubert, M., Giese, N., Reber, H.A., Hines, O.J., Giese, T., Ceyhan, G.O., Müller, M., Büchler, M.W., Friess, H. Ann. Surg. (2005)
- Effects of Delta1 and Jagged1 on early human hematopoiesis: correlation with expression of notch signaling-related genes in CD34+ cells. Neves, H., Weerkamp, F., Gomes, A.C., Naber, B.A., Gameiro, P., Becker, J.D., Lúcio, P., Clode, N., van Dongen, J.J., Staal, F.J., Parreira, L. Stem Cells (2006)
- Notch ligands, Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines. Tohda, S., Murata-Ohsawa, M., Sakano, S., Nara, N. Int. J. Oncol. (2003)
- Distribution of presenilin 1 and 2 and their relation to Notch receptors and ligands in human embryonic/foetal central nervous system. Kostyszyn, B., Cowburn, R.F., Seiger, A., Kjaeldgaard, A., Sundström, E. Brain Res. Dev. Brain Res. (2004)
- Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation. Jaleco, A.C., Neves, H., Hooijberg, E., Gameiro, P., Clode, N., Haury, M., Henrique, D., Parreira, L. J. Exp. Med. (2001)
- Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1. Ohishi, K., Varnum-Finney, B., Flowers, D., Anasetti, C., Myerson, D., Bernstein, I.D. Blood (2000)
- Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor. Gupta-Rossi, N., Six, E., LeBail, O., Logeat, F., Chastagner, P., Olry, A., Israël, A., Brou, C. J. Cell Biol. (2004)
- Tumour necrosis factor (TNF) gene polymorphism in Crohn's disease (CD): influence on disease behaviour? Louis, E., Peeters, M., Franchimont, D., Seidel, L., Fontaine, F., Demolin, G., Croes, F., Dupont, P., Davin, L., Omri, S., Rutgeerts, P., Belaiche, J. Clin. Exp. Immunol. (2000)
- The Notch ligand, Delta-1, alters retinoic acid (RA)-induced neutrophilic differentiation into monocytic and reduces RA-induced apoptosis in NB4 cells. Murata-Ohsawa, M., Tohda, S., Kogoshi, H., Sakano, S., Nara, N. Leuk. Res. (2005)
- Ornithine decarboxylase prevents tumor necrosis factor alpha-induced apoptosis by decreasing intracellular reactive oxygen species. Liu, G.Y., Hung, Y.C., Hsu, P.C., Liao, Y.F., Chang, W.H., Tsay, G.J., Hung, H.C. Apoptosis (2005)
- Proneural bHLH and Brn Proteins Coregulate a Neurogenic Program through Cooperative Binding to a Conserved DNA Motif. Castro, D.S., Skowronska-Krawczyk, D., Armant, O., Donaldson, I.J., Parras, C., Hunt, C., Critchley, J.A., Nguyen, L., Gossler, A., G??ttgens, B., Matter, J.M., Guillemot, F. Dev. Cell (2006)
- FGF-dependent Notch signaling maintains the spinal cord stem zone. Akai, J., Halley, P.A., Storey, K.G. Genes Dev. (2005)
- The Notch ligand, Delta-1, partially inhibits GM-CSF-induced differentiation and apoptosis along with reducing the cleavage of PARP in U937 cells. Murata-Ohsawa, M., Tohda, S., Sakano, S., Nara, N. Int. J. Mol. Med. (2004)
- ICAM-3, the third LFA-1 counterreceptor, is a co-stimulatory molecule for both resting and activated T lymphocytes. Hernandez-Caselles, T., Rubio, G., Campanero, M.R., del Pozo, M.A., Muro, M., Sanchez-Madrid, F., Aparicio, P. Eur. J. Immunol. (1993)
- Gamma delta T cells in rhesus monkeys and their response to simian immunodeficiency virus (SIV) infection. Gan, Y.H., Pauza, C.D., Malkovsky, M. Clin. Exp. Immunol. (1995)
- Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation. Shimizu, K., Chiba, S., Saito, T., Kumano, K., Takahashi, T., Hirai, H. J. Biol. Chem. (2001)
- The Notch ligand, Delta-1, reduces TNF-alpha-induced growth suppression and apoptosis by decreasing activation of caspases in U937 cells. Murata-Ohsawa, M., Tohda, S., Kogoshi, H., Nara, N. Int. J. Mol. Med. (2004)
- Effects of human yolk sac endothelial cells on supporting expansion of hematopoietic stem/progenitor cells from cord blood. Hu, L., Cheng, L., Wang, J., Zhao, H., Duan, H., Lu, G. Cell Biol. Int. (2006)
- Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells. Karanu, F.N., Murdoch, B., Miyabayashi, T., Ohno, M., Koremoto, M., Gallacher, L., Wu, D., Itoh, A., Sakano, S., Bhatia, M. Blood (2001)
- Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood. Haddad, R., Guardiola, P., Izac, B., Thibault, C., Radich, J., Delezoide, A.L., Baillou, C., Lemoine, F.M., Gluckman, J.C., Pflumio, F., Canque, B. Blood (2004)
- Bone marrow-derived hemopoietic precursors commit to the T cell lineage only after arrival in the thymic microenvironment. Heinzel, K., Benz, C., Martins, V.C., Haidl, I.D., Bleul, C.C. J. Immunol. (2007)
- Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling. Varnum-Finney, B., Wu, L., Yu, M., Brashem-Stein, C., Staats, S., Flowers, D., Griffin, J.D., Bernstein, I.D. J. Cell. Sci. (2000)