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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Retinal Neovascularization

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Disease relevance of Retinal Neovascularization


High impact information on Retinal Neovascularization


Chemical compound and disease context of Retinal Neovascularization


Biological context of Retinal Neovascularization


Anatomical context of Retinal Neovascularization


Gene context of Retinal Neovascularization


Analytical, diagnostic and therapeutic context of Retinal Neovascularization


  1. Selective stimulation of VEGFR-1 prevents oxygen-induced retinal vascular degeneration in retinopathy of prematurity. Shih, S.C., Ju, M., Liu, N., Smith, L.E. J. Clin. Invest. (2003) [Pubmed]
  2. Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy. Al-Shabrawey, M., Bartoli, M., El-Remessy, A.B., Platt, D.H., Matragoon, S., Behzadian, M.A., Caldwell, R.W., Caldwell, R.B. Am. J. Pathol. (2005) [Pubmed]
  3. Leptin stimulates ischemia-induced retinal neovascularization: possible role of vascular endothelial growth factor expressed in retinal endothelial cells. Suganami, E., Takagi, H., Ohashi, H., Suzuma, K., Suzuma, I., Oh, H., Watanabe, D., Ojima, T., Suganami, T., Fujio, Y., Nakao, K., Ogawa, Y., Yoshimura, N. Diabetes (2004) [Pubmed]
  4. Effects of insulin-like growth factor-1 on retinal endothelial cell glucose transport and proliferation. DeBosch, B.J., Baur, E., Deo, B.K., Hiraoka, M., Kumagai, A.K. J. Neurochem. (2001) [Pubmed]
  5. Selective suppression of pathologic, but not physiologic, retinal neovascularization by blocking the angiotensin II type 1 receptor. Nagai, N., Noda, K., Urano, T., Kubota, Y., Shinoda, H., Koto, T., Shinoda, K., Inoue, M., Shiomi, T., Ikeda, E., Tsubota, K., Suda, T., Oike, Y., Ishida, S. Invest. Ophthalmol. Vis. Sci. (2005) [Pubmed]
  6. Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity. Brooks, P.C., Silletti, S., von Schalscha, T.L., Friedlander, M., Cheresh, D.A. Cell (1998) [Pubmed]
  7. Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor. Smith, L.E., Shen, W., Perruzzi, C., Soker, S., Kinose, F., Xu, X., Robinson, G., Driver, S., Bischoff, J., Zhang, B., Schaeffer, J.M., Senger, D.R. Nat. Med. (1999) [Pubmed]
  8. Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization. Hammes, H.P., Brownlee, M., Jonczyk, A., Sutter, A., Preissner, K.T. Nat. Med. (1996) [Pubmed]
  9. Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Dawson, D.W., Volpert, O.V., Gillis, P., Crawford, S.E., Xu, H., Benedict, W., Bouck, N.P. Science (1999) [Pubmed]
  10. Essential role of growth hormone in ischemia-induced retinal neovascularization. Smith, L.E., Kopchick, J.J., Chen, W., Knapp, J., Kinose, F., Daley, D., Foley, E., Smith, R.G., Schaeffer, J.M. Science (1997) [Pubmed]
  11. c-abl is required for the development of hyperoxia-induced retinopathy. Nunes, I., Higgins, R.D., Zanetta, L., Shamamian, P., Goff, S.P. J. Exp. Med. (2001) [Pubmed]
  12. Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy. Robinson, G.S., Pierce, E.A., Rook, S.L., Foley, E., Webb, R., Smith, L.E. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  13. Loss of p53 compensates for alpha v-integrin function in retinal neovascularization. Strömblad, S., Fotedar, A., Brickner, H., Theesfeld, C., Aguilar de Diaz, E., Friedlander, M., Cheresh, D.A. J. Biol. Chem. (2002) [Pubmed]
  14. Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina. Kramerov, A.A., Saghizadeh, M., Pan, H., Kabosova, A., Montenarh, M., Ahmed, K., Penn, J.S., Chan, C.K., Hinton, D.R., Grant, M.B., Ljubimov, A.V. Am. J. Pathol. (2006) [Pubmed]
  15. Regulation of vascular endothelial growth factor expression by insulin-like growth factor I. Punglia, R.S., Lu, M., Hsu, J., Kuroki, M., Tolentino, M.J., Keough, K., Levy, A.P., Levy, N.S., Goldberg, M.A., D'Amato, R.J., Adamis, A.P. Diabetes (1997) [Pubmed]
  16. The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. SanGiovanni, J.P., Chew, E.Y. Progress in retinal and eye research. (2005) [Pubmed]
  17. Conditional knockdown of tubedown-1 in endothelial cells leads to neovascular retinopathy. Wall, D.S., Gendron, R.L., Good, W.V., Miskiewicz, E., Woodland, M., Leblanc, K., Paradis, H. Invest. Ophthalmol. Vis. Sci. (2004) [Pubmed]
  18. Prolactins are natural inhibitors of angiogenesis in the retina. Aranda, J., Rivera, J.C., Jeziorski, M.C., Riesgo-Escovar, J., Nava, G., López-Barrera, F., Quiróz-Mercado, H., Berger, P., Martínez de la Escalera, G., Clapp, C. Invest. Ophthalmol. Vis. Sci. (2005) [Pubmed]
  19. The urokinase/urokinase receptor system in retinal neovascularization: inhibition by A6 suggests a new therapeutic target. McGuire, P.G., Jones, T.R., Talarico, N., Warren, E., Das, A. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  20. Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization. Kondo, T., Vicent, D., Suzuma, K., Yanagisawa, M., King, G.L., Holzenberger, M., Kahn, C.R. J. Clin. Invest. (2003) [Pubmed]
  21. Loss of the antiangiogenic pigment epithelium-derived factor in patients with angiogenic eye disease. Spranger, J., Osterhoff, M., Reimann, M., Möhlig, M., Ristow, M., Francis, M.K., Cristofalo, V., Hammes, H.P., Smith, G., Boulton, M., Pfeiffer, A.F. Diabetes (2001) [Pubmed]
  22. EphrinA1 inhibits vascular endothelial growth factor-induced intracellular signaling and suppresses retinal neovascularization and blood-retinal barrier breakdown. Ojima, T., Takagi, H., Suzuma, K., Oh, H., Suzuma, I., Ohashi, H., Watanabe, D., Suganami, E., Murakami, T., Kurimoto, M., Honda, Y., Yoshimura, N. Am. J. Pathol. (2006) [Pubmed]
  23. Vascular endothelial growth factor is present in glial cells of the retina and optic nerve of human subjects with nonproliferative diabetic retinopathy. Amin, R.H., Frank, R.N., Kennedy, A., Eliott, D., Puklin, J.E., Abrams, G.W. Invest. Ophthalmol. Vis. Sci. (1997) [Pubmed]
  24. PKC/MAPK signaling suppression by retinal pericyte conditioned medium prevents retinal endothelial cell proliferation. Kondo, T., Hosoya, K., Hori, S., Tomi, M., Ohtsuki, S., Terasaki, T. J. Cell. Physiol. (2005) [Pubmed]
  25. Basic fibroblast growth factor is neither necessary nor sufficient for the development of retinal neovascularization. Ozaki, H., Okamoto, N., Ortega, S., Chang, M., Ozaki, K., Sadda, S., Vinores, M.A., Derevjanik, N., Zack, D.J., Basilico, C., Campochiaro, P.A. Am. J. Pathol. (1998) [Pubmed]
  26. Blockade of nitric-oxide synthase reduces choroidal neovascularization. Ando, A., Yang, A., Nambu, H., Campochiaro, P.A. Mol. Pharmacol. (2002) [Pubmed]
  27. Potential role of the angiopoietin/tie2 system in ischemia-induced retinal neovascularization. Takagi, H., Koyama, S., Seike, H., Oh, H., Otani, A., Matsumura, M., Honda, Y. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  28. Role of NF-kappaB-mediated interleukin-8 expression in intraocular neovascularization. Yoshida, A., Yoshida, S., Khalil, A.K., Ishibashi, T., Inomata, H. Invest. Ophthalmol. Vis. Sci. (1998) [Pubmed]
  29. Adult human hematopoietic cells provide functional hemangioblast activity. Cogle, C.R., Wainman, D.A., Jorgensen, M.L., Guthrie, S.M., Mames, R.N., Scott, E.W. Blood (2004) [Pubmed]
  30. Angiopoietin-2 enhances retinal vessel sensitivity to vascular endothelial growth factor. Oshima, Y., Deering, T., Oshima, S., Nambu, H., Reddy, P.S., Kaleko, M., Connelly, S., Hackett, S.F., Campochiaro, P.A. J. Cell. Physiol. (2004) [Pubmed]
  31. Retinal ischemia with neovascularization in cisplatin related retinal toxicity. Kwan, A.S., Sahu, A., Palexes, G. Am. J. Ophthalmol. (2006) [Pubmed]
  32. Unilateral retinal vasculitis, branch retinal artery occlusion and subsequent retinal neovascularization in Crohn's disease. Saatci, O.A., Koçak, N., Durak, I., Ergin, M.H. International ophthalmology. (2001) [Pubmed]
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