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Chemical Compound Review

SureCN133366     ethyl 3-aminobenzoate

Synonyms: E10505_ALDRICH, AG-C-10939, ACMC-209m38, ANW-32898, NSC-39593, ...
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Disease relevance of Tricaine


Psychiatry related information on Tricaine


High impact information on Tricaine


Biological context of Tricaine


Anatomical context of Tricaine

  • Two experimental sets of rainbow trout microsomes were tested; one representing in vivo or surgical tricaine exposures and the other representing in vitro tissue/organ collection tricaine exposures [13].
  • Transient use of tricaine to remove the telencephalon has no residual effects on physiological recordings of supramedullary/dorsal neurons of the cunner, Tautogolabrus adspersus [14].
  • Anesthesia with tricaine (MS222) and exposure of the pericardium for blood sampling from the ventral aorta affected plasma ANP and VNP levels [15].
  • We analyze the effect of a common anesthetic, tricaine (MS-222), on the metabolism of foreign compounds in the liver and duodenum of the splake [16].
  • 1. Glucose production by freshly isolated hepatocytes from rainbow trout was studied after anaesthesia of the animals with 2-phenoxy ethanol (2PE) or tricaine methanesulphonate (MS222) [17].

Associations of Tricaine with other chemical compounds


Analytical, diagnostic and therapeutic context of Tricaine


  1. Studies on the comparative pharmacology and selective toxicity of tricaine methanesulfonate: metabolism as a basis of the selective toxicity in poikilotherms. Wayson, K.A., Downes, H., Lynn, R.K., Gerber, N. J. Pharmacol. Exp. Ther. (1976) [Pubmed]
  2. Exhaustive exercise, animal stress, and environmental hypercapnia on motility of sperm of steelhead trout (Oncorhynchus mykiss). Zuccarelli, M.D., Ingermann, R.L. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. (2007) [Pubmed]
  3. Comparative efficacy of tricaine methanesulfonate and clove oil for use as anesthetics in red pacu (Piaractus brachypomus). Sladky, K.K., Swanson, C.R., Stoskopf, M.K., Loomis, M.R., Lewbart, G.A. Am. J. Vet. Res. (2001) [Pubmed]
  4. Muscle weakness during tricaine anesthesia. Herr, V.D., Sonnenburg, D.C., Courogen, P.M., Fiamengo, S.A., Downes, H. Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. (1995) [Pubmed]
  5. Molecular forms of acetylcholinesterase in Xenopus muscle. Lappin, R.I., Rubin, L.L. Dev. Biol. (1985) [Pubmed]
  6. Muscle activity and the loss of electrical coupling between striated muscle cells in Xenopus embryos. Armstrong, D.L., Turin, L., Warner, A.E. J. Neurosci. (1983) [Pubmed]
  7. In vivo development of cholinesterase at a neuromuscular junction in the absence of motor activity in Xenopus laevis. Cohen, M.W., Greschner, M., Tucci, M. J. Physiol. (Lond.) (1984) [Pubmed]
  8. Excitatory and inhibitory effects of tricaine (MS-222) on fictive breathing in isolated bullfrog brain stem. Hedrick, M.S., Winmill, R.E. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2003) [Pubmed]
  9. The interaction of Candida boidinii formate dehydrogenase with a new family of chimeric biomimetic dye-ligands. Labrou, N.E., Clonis, Y.D. Arch. Biochem. Biophys. (1995) [Pubmed]
  10. Retinal toxicity associated with occupational exposure to the fish anesthetic MS-222. Bernstein, P.S., Digre, K.B., Creel, D.J. Am. J. Ophthalmol. (1997) [Pubmed]
  11. Differential effects of anesthetics on electrical properties of the rainbow trout (Oncorhynchus mykiss) heart. Cotter, P.A., Rodnick, K.J. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. (2006) [Pubmed]
  12. Hepatic microsomes from freshwater fish--II. Reduction of benzo(a)pyrene metabolism by the fish anesthetics quinaldine sulfate and tricaine. Fabacher, D.L. Comp. Biochem. Physiol. C, Comp. Pharmacol. (1982) [Pubmed]
  13. Effects of anesthesia (tricaine methanesulfonate, MS222) on liver biotransformation in rainbow trout (Oncorhynchus mykiss). Kolanczyk, R.C., Fitzsimmons, P.N., McKim, J.M., Erickson, R.J., Schmieder, P.K. Aquat. Toxicol. (2003) [Pubmed]
  14. Transient use of tricaine to remove the telencephalon has no residual effects on physiological recordings of supramedullary/dorsal neurons of the cunner, Tautogolabrus adspersus. Zottoli, S.J., Burton, O.T., Chambers, J.A., Eseh, R., Gutiérrez, L.M., Kron, M.M. Biol. Bull. (2003) [Pubmed]
  15. Atrial and ventricular natriuretic peptide concentrations in plasma of freshwater- and seawater-adapted eels. Kaiya, H., Takei, Y. Gen. Comp. Endocrinol. (1996) [Pubmed]
  16. Tricaine (MS-222) induced modification on the metabolism of foreign compounds in the liver and duodenal mucosa of the splake (Salvelinus fontinalis X Salvelinus namaycush). Laitinen, M., Nieminen, M., Pasanen, P., Hietanen, E. Acta pharmacologica et toxicologica. (1981) [Pubmed]
  17. Inhibitory effect of anaesthesia with 2-phenoxyethanol as compared to MS222 on glucose release in isolated hepatocytes from rainbow trout (Salmo gairdneri). Pucéat, M., Garin, D., Fréminet, A. Comparative biochemistry and physiology. A, Comparative physiology. (1989) [Pubmed]
  18. The effects of tricaine methanesulfonate (MS-222) on plasma nonesterified fatty acids in rainbow trout, Oncorhynchus mykiss. Harrington, A.J., Russell, K.A., Singer, T.D., Ballantyne, J.S. Lipids (1991) [Pubmed]
  19. Effects of tricaine methane sulphonate (M.S. 222) on the blood glucose levels in adult salamanders (Diemictylus viridescens). Vethamany-Globus, S., Globus, M., Fraser, I. Experientia (1977) [Pubmed]
  20. A scanning electron-microscopic study of tongue development in the frog Rana pipiens. Paulson, R.B., Alley, K.E., Salata, L.J., Whitmyer, C.C. Arch. Oral Biol. (1995) [Pubmed]
  21. Tricaine (MS-222): effects on ionic conductances of squid axon membranes. Frazier, D.T., Narahashi, T. Eur. J. Pharmacol. (1975) [Pubmed]
  22. Determination of residues of tricaine in fish using liquid chromatography tandem mass spectrometry. Scherpenisse, P., Bergwerff, A.A. Anal. Chim. Acta (2007) [Pubmed]
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