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Chemical Compound Review

Noltran     dimethoxy-sulfanylidene- (3,5,6...

Synonyms: Zertell, Reldan, Tumar, Dowco 214, OMS-1155, ...
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Disease relevance of Trichlormethylfos


High impact information on Trichlormethylfos


Chemical compound and disease context of Trichlormethylfos


Biological context of Trichlormethylfos


Anatomical context of Trichlormethylfos

  • Chlorpyrifos-methyl dissipation in a small adjacent water body following application to citrus [13].
  • Uterine and vaginal weight, uterine epithelial cell height were not affected by the treatment of CPM (2, 10, 50, 250 mg/kg) [2].
  • Substantial amounts (0.615-4.15 mg/L) of chlorpyrifos-methyl were detected in all blood samples, and the order of its concentrations was as follows: pulmonary vessel blood > thoracic inferior vena caval blood > blood in the right cardiac chambers > blood in the left cardiac chambers approximately thoracic aortic blood > right femoral venous blood [14].
  • In conclusion, CPM dose not show estrogenic and anti-estrogenic activity in immature female rats, but it represents anti-androgenic activity by inhibition of the TP-stimulated increase of the weight of accessory sex organs [2].
  • While CPM induced the increase of relative adrenal gland weight, CPM 50mg/kg decreased the weights of CV/CG, VP, CG and LABC without change of GP without changing of GP when it was treated with TP [2].

Associations of Trichlormethylfos with other chemical compounds


Gene context of Trichlormethylfos

  • Longevity and lifetime fecundity were significantly reduced after topical application of LC10, LC20, and LC60's of chlorpyrifos-methyl to 2-d-old female German cockroaches, Blattella germanica (L.). Low concentrations (LC10 and LC20) often resulted in failure of the first ootheca to hatch [20].
  • BACKGROUND & OBJECTIVES: Indoor residual spraying of Reldan 40% EC @ 0.5 and 1 g/m2 was done in Tatarpur and Chauna villages, respectively in Dhaulana PHC, Distt [21].

Analytical, diagnostic and therapeutic context of Trichlormethylfos


  1. Investigation of acute toxicity of chlorpyrifos-methyl on Nile tilapia (Oreochromis niloticus L.) larvae. Gül, A. Chemosphere (2005) [Pubmed]
  2. Chlropyrifos-methyl shows anti-androgenic activity without estrogenic activity in rats. Kang, H.G., Jeong, S.H., Cho, J.H., Kim, D.G., Park, J.M., Cho, M.H. Toxicology (2004) [Pubmed]
  3. Monitoring of insecticides resistance in main malaria vectors in a malarious area of Kahnooj district, Kerman province, southeastern Iran. Vatandoost, H., Mashayekhi, M., Abaie, M.R., Aflatoonian, M.R., Hanafi-Bojd, A.A., Sharifi, I. Journal of vector borne diseases. (2005) [Pubmed]
  4. The relationship of urinary metabolites of carbaryl/naphthalene and chlorpyrifos with human semen quality. Meeker, J.D., Ryan, L., Barr, D.B., Herrick, R.F., Bennett, D.H., Bravo, R., Hauser, R. Environ. Health Perspect. (2004) [Pubmed]
  5. Nucleophilic substitution of phosphorothionate ester pesticides with bisulfide (HS-) and polysulfides (S(n)2-). Wu, T., Gan, Q., Jans, U. Environ. Sci. Technol. (2006) [Pubmed]
  6. Nucleophilic substitution reactions of chlorpyrifos-methyl with sulfur species. Wu, T., Jans, U. Environ. Sci. Technol. (2006) [Pubmed]
  7. Changes in cross-resistance spectrum resulting from methyl parathion selection of Culex tarsalis Coq. Apperson, C.S., Georghiou, G.P. Am. J. Trop. Med. Hyg. (1975) [Pubmed]
  8. Thyroid hormones in relation to urinary metabolites of non-persistent insecticides in men of reproductive age. Meeker, J.D., Barr, D.B., Hauser, R. Reprod. Toxicol. (2006) [Pubmed]
  9. Acute toxicity of several organophosphorous insecticides and protection by cholinergic antagonists and 2-PAM on Artemia salina larvae. Sánchez-Fortún, S., Sanz, F., Barahona, M.V. Arch. Environ. Contam. Toxicol. (1996) [Pubmed]
  10. Insecticidal, acaricidal and synergistic effects of soosan, Pancratium maritimum extracts and constituents. Abbassy, M.A., el-Gougary, O.A., el-Hamady, S., Sholo, M.A. Journal of the Egyptian Society of Parasitology. (1998) [Pubmed]
  11. Vapor phase toxicity of plant essential oils to Cadra cautella (Lepidoptera: Pyralidae). Sim, M.J., Choi, D.R., Ahn, Y.J. J. Econ. Entomol. (2006) [Pubmed]
  12. Reaction of chlorpyrifos-methyl in aqueous hydrogen sulfide/bisulfide solutions. Jans, U., Miah, M.H. J. Agric. Food Chem. (2003) [Pubmed]
  13. Chlorpyrifos-methyl dissipation in a small adjacent water body following application to citrus. Padovani, L., Capri, E. Chemosphere (2005) [Pubmed]
  14. Pitfalls when determining tissue distributions of organophosphorus chemicals: sodium fluoride accelerates chemical degradation. Moriya, F., Hashimoto, Y., Kuo, T.L. Journal of analytical toxicology. (1999) [Pubmed]
  15. Bioavailability and biological activity of wheat-bound chlorpyrifos-methyl residues in rats. Neskovic, N.K., Karan, V., Budimir, M., Vojinovic, V., Gasic, S., Vitorovic, S.L. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. (1992) [Pubmed]
  16. The hydrolysis rate of chlorpyrifos, O-O-diethyl O-(3,5,6-trichloro-2-pyridyl) phosphorothioate, and its dimethyl analog, chlorpyrifos-methyl, in dilute aqueous solution. Meikle, R.W., Youngson, C.R. Arch. Environ. Contam. Toxicol. (1978) [Pubmed]
  17. Evaluation of temephos and chlorpyrifos-methyl against Culex pipiens (Diptera: Culicidae) larvae in septic tanks in Antalya, Turkey. Cetin, H., Yanikoglu, A., Kocak, O., Cilek, J.E. J. Med. Entomol. (2006) [Pubmed]
  18. Biochemical mechanisms of resistance in strains of Oryzaephilus surinamensis (Coleoptera: Silvanidae) resistant to malathion and chlorpyrifos-methyl. Lee, S.E., Lees, E.M. J. Econ. Entomol. (2001) [Pubmed]
  19. Biological monitoring of exposure to organophosphorus insecticides by assay of urinary alkylphosphates: influence of protective measures during manual operations with treated plants. Aprea, C., Sciarra, G., Sartorelli, P., Desideri, E., Amati, R., Sartorelli, E. International archives of occupational and environmental health. (1994) [Pubmed]
  20. Sublethal effects of chlorpyrifos-methyl on reproduction in female German cockroaches (Dictyoptera: Blattellidae). Hamilton, R.L., Schal, C. J. Econ. Entomol. (1990) [Pubmed]
  21. Impact of residual spraying of Reldan against Anopheles culicifacies in selected villages of District Ghaziabad (Uttar pradesh), India. Ansari, M.A., Razdan, R.K. Journal of vector borne diseases. (2004) [Pubmed]
  22. Toxicological interactions of chlorpyrifos and methyl mercury in the amphipod, Hyalella azteca. Steevens, J.A., Benson, W.H. Toxicol. Sci. (1999) [Pubmed]
  23. Electrochemical bioassay for the investigation of chlorpyrifos-methyl in vine samples. Del Carlo, M., Mascini, M., Pepe, A., Compagnone, D., Mascini, M. J. Agric. Food Chem. (2002) [Pubmed]
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