Chemical Compound Review:
Anodynin 1,5-dimethyl-2-phenyl- pyrazol-3-one
Synonyms:
Auralgan, Azophene, Fenazona, Fenazone, Methozin, ...
- Effect of age on antipyrine metabolism in patients with gastric cancer. Higuchi, T., Nakamura, T., Uchino, H. J. Natl. Cancer Inst. (1980)
- Drug metabolism in liver disease. Identification of patients with impaired hepatic drug metabolism. Farrell, G.C., Cooksley, W.G., Hart, P., Powell, L.W. Gastroenterology (1978)
- Induction of hepatic microsomal enzymes after brief administration of rifampicin in man. Miguet, J.P., Mavier, P., Soussy, C.J., Dhumeaux, D. Gastroenterology (1977)
- Spironolactone and enzyme induction in patients with alcoholic cirrhosis. Miguet, J.P., Vuitton, D., Thebault-Lucas, A., Joanne, C., Dhumeaux, D. Gastroenterology (1980)
- Prophylaxis of neonatal jaundice with maternal antipyrine treatment. Lewis, P.J., Friedman, L.A. Lancet (1979)
- Influence of short-term water deprivation on antipyrine disposition. Prasad, P., Jung, D., Niazi, S. Journal of pharmaceutical sciences. (1985)
- Relationships among liver and kidney volumes, lean body mass and drug clearance. Nawaratne, S., Brien, J.E., Seeman, E., Fabiny, R., Zalcberg, J., Cosolo, W., Angus, P., Morgan, D.J. British journal of clinical pharmacology. (1998)
- Hepatic antipyrine metabolism in athletes. Orioli, S., Bandinelli, I., Birardi, A., Chieca, R., Buzzelli, G., Chiarantini, E. The Journal of sports medicine and physical fitness. (1990)
- Phase I and pharmacologic studies of topotecan in patients with impaired hepatic function. O'Reilly, S., Rowinsky, E., Slichenmyer, W., Donehower, R.C., Forastiere, A., Ettinger, D., Chen, T.L., Sartorius, S., Bowling, K., Smith, J., Brubaker, A., Lubejko, B., Ignacio, V., Grochow, L.B. J. Natl. Cancer Inst. (1996)
- Verapamil favorably influences hepatic microvascular exchange and function in rats with cirrhosis of the liver. Reichen, J., Le, M. J. Clin. Invest. (1986)
- Polymorphism of theophylline metabolism in man. Miller, C.A., Slusher, L.B., Vesell, E.S. J. Clin. Invest. (1985)
- Direct evidence for the intact hepatocyte theory in patients with liver cirrhosis. Kawasaki, S., Imamura, H., Bandai, Y., Sanjo, K., Idezuki, Y. Gastroenterology (1992)
- Accelerated improvement of alcoholic liver disease with enteral nutrition. Kearns, P.J., Young, H., Garcia, G., Blaschke, T., O'Hanlon, G., Rinki, M., Sucher, K., Gregory, P. Gastroenterology (1992)
- Relationship between metabolic clearance rate of antipyrine and hepatic microsomal drug-oxidizing enzyme activities in humans without liver disease. Vuitton, D., Miguet, J.P., Camelot, G., Delafin, C., Joanne, C., Bechtel, P., Gillet, M., Carayon, P. Gastroenterology (1981)
- Glucuronidation of oxazepam is not spared in patients with hepatic encephalopathy. Sonne, J., Andreasen, P.B., Loft, S., Døssing, M., Andreasen, F. Hepatology (1990)
- Proceedings: Antipyrine, lingocaine and paracetamol metabolism in chronic liver disease. Forrest, J.A., Finlayson, N.D., Adjepon-Yamoah, K.K., Prescott, L.F. Gut (1975)
- Hepatic clearances of antipyrine, indocyanine green, and galactose in normal subjects and in patients with chronic liver diseases. Kawasaki, S., Sugiyama, Y., Iga, T., Hanano, M., Beppu, T., Sugiura, M., Sanjo, K., Idezuki, Y. Clin. Pharmacol. Ther. (1988)
- Plasma clearance of propranolol and sotalol and hepatic drug-metabolizing enzyme activity. Sotaniemi, E.A., Anttila, M., Pelkonen, R.O., Järvensivu, P., Sundquist, H. Clin. Pharmacol. Ther. (1979)
- Ursodeoxycholic acid in primary biliary cirrhosis: results of a controlled double-blind trial. Leuschner, U., Fischer, H., Kurtz, W., Güldütuna, S., Hübner, K., Hellstern, A., Gatzen, M., Leuschner, M. Gastroenterology (1989)
- Alprazolam kinetics in the elderly. Relation to antipyrine disposition. Greenblatt, D.J., Divoll, M., Abernethy, D.R., Moschitto, L.J., Smith, R.B., Shader, R.I. Arch. Gen. Psychiatry (1983)
- Impairment of antipyrine clearance in humans by propranolol. Greenblatt, D.J., Franke, K., Huffman, D.H. Circulation (1978)
- Acetaminophen-induced hypothermia in mice is mediated by a prostaglandin endoperoxide synthase 1 gene-derived protein. Ayoub, S.S., Botting, R.M., Goorha, S., Colville-Nash, P.R., Willoughby, D.A., Ballou, L.R. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Genetic variation in rates of antipyrine metabolite formation: a study in uninduced twins. Penno, M.B., Dvorchik, B.H., Vesell, E.S. Proc. Natl. Acad. Sci. U.S.A. (1981)
- Isolation of a novel endogenous opiate analgesic from human blood. Pert, C.B., Pert, A., Tallman, J.F. Proc. Natl. Acad. Sci. U.S.A. (1976)
- High-pressure liquid chromatographic analysis of benzo(a)pyrene metabolism by human lymphocytes from donors of different aryl hydrocarbon hydroxylase inducibility and antipyrine half-lives. Gurtoo, H.L., Vaught, J.B., Marinello, A.J., Paigen, B., Gessner, T., Bolanowska, W. Cancer Res. (1980)
- Renal sodium retention in cirrhosis: tubular site and relation to hepatic dysfunction. Wood, L.J., Massie, D., McLean, A.J., Dudley, F.J. Hepatology (1988)
- Alterations in transfer and lipid distribution of arachidonic acid in placentas of diabetic pregnancies. Kuhn, D.C., Crawford, M.A., Stuart, M.J., Botti, J.J., Demers, L.M. Diabetes (1990)
- Antipyrine disposition in milk and saliva of lactating women. Berlin, C.M., Vesell, E.S. Clin. Pharmacol. Ther. (1982)
- COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Chandrasekharan, N.V., Dai, H., Roos, K.L., Evanson, N.K., Tomsik, J., Elton, T.S., Simmons, D.L. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Unresponsiveness of hepatic nitrogen metabolism to glucagon infusion in patients with cirrhosis: dependence on liver cell failure. Fabbri, A., Marchesini, G., Bianchi, G., Bugianesi, E., Bortoluzzi, L., Zoli, M., Pisi, E. Hepatology (1993)
- Factors affecting epirubicin pharmacokinetics and toxicity: evidence against using body-surface area for dose calculation. Gurney, H.P., Ackland, S., Gebski, V., Farrell, G. J. Clin. Oncol. (1998)
- Kinetic evidence for heterogeneous responsiveness of mixed function oxidase isozymes to inhibition and induction by allylisopropylacetamide in chick embryo liver. Rifkind, A.B., Troeger, M., Muschick, H. J. Biol. Chem. (1982)
- Antipyrine as a probe for human oxidative drug metabolism: identification of the cytochrome P450 enzymes catalyzing 4-hydroxyantipyrine, 3-hydroxymethylantipyrine, and norantipyrine formation. Engel, G., Hofmann, U., Heidemann, H., Cosme, J., Eichelbaum, M. Clin. Pharmacol. Ther. (1996)
- Effect of zidovudine therapy in patients with HIV infection on endogenous interferon plasma levels and the hepatic cytochrome P450 enzyme system. Brockmeyer, N.H., Barthel, B., Mertins, L., Goos, M. Chemotherapy. (1998)
- Evaluation of the influence of diabetes mellitus on antipyrine metabolism and CYP1A2 and CYP2D6 activity. Matzke, G.R., Frye, R.F., Early, J.J., Straka, R.J., Carson, S.W. Pharmacotherapy (2000)
- Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure. Carcillo, J.A., Doughty, L., Kofos, D., Frye, R.F., Kaplan, S.S., Sasser, H., Burckart, G.J. Intensive care medicine. (2003)
- Lack of enzyme induction with oxcarbazepine (600 mg daily) in healthy subjects. Larkin, J.G., McKee, P.J., Forrest, G., Beastall, G.H., Park, B.K., Lowrie, J.I., Lloyd, P., Brodie, M.J. British journal of clinical pharmacology. (1991)
- Metabolic disposition of antipyrine in patients with lung cancer. Tschanz, C., Hignite, C.E., Huffman, D.H., Azarnoff, D.L. Cancer Res. (1977)
- Drug metabolism in hepatosplenic schistosomiasis in the Sudan: a study with antipyrine. Homeida, M., Salih, S.Y., Branch, R.A. Gut (1978)
- Altered elimination of antipyrine in patients with acute viral hepatitis. Burnett, D.A., Barak, A.J., Tuma, D.J., Sorrell, M.F. Gut (1976)
- Comparative evaluation of the effects of isradipine and diltiazem on antipyrine and indocyanine green clearances in elderly volunteers. Klockowski, P.M., Lener, M.E., Sirgo, M.A., Rocci, M.L. Clin. Pharmacol. Ther. (1990)