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Chemical Compound Review

KMTB     4-methylsulfanyl-2-oxo- butanoic acid

Synonyms: AG-K-68154, CHEBI:33574, HMDB01553, AC1Q5RHU, CTK5A8242, ...
 
 
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Disease relevance of S-Methyl-alpha-ketobutyric acid

 

High impact information on S-Methyl-alpha-ketobutyric acid

 

Biological context of S-Methyl-alpha-ketobutyric acid

 

Anatomical context of S-Methyl-alpha-ketobutyric acid

 

Associations of S-Methyl-alpha-ketobutyric acid with other chemical compounds

 

Gene context of S-Methyl-alpha-ketobutyric acid

 

Analytical, diagnostic and therapeutic context of S-Methyl-alpha-ketobutyric acid

References

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  2. Tyrosine aminotransferase catalyzes the final step of methionine recycling in Klebsiella pneumoniae. Heilbronn, J., Wilson, J., Berger, B.J. J. Bacteriol. (1999) [Pubmed]
  3. BRANCHED-CHAIN AMINOTRANSFERASE4 Is Part of the Chain Elongation Pathway in the Biosynthesis of Methionine-Derived Glucosinolates in Arabidopsis. Schuster, J., Knill, T., Reichelt, M., Gershenzon, J., Binder, S. Plant Cell (2006) [Pubmed]
  4. Methylthioadenosine phosphorylase regulates ornithine decarboxylase by production of downstream metabolites. Subhi, A.L., Diegelman, P., Porter, C.W., Tang, B., Lu, Z.J., Markham, G.D., Kruger, W.D. J. Biol. Chem. (2003) [Pubmed]
  5. A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K. Stevens, J.L., Robbins, J.D., Byrd, R.A. J. Biol. Chem. (1986) [Pubmed]
  6. Ferric iron and superoxide ions are required for the killing of cultured hepatocytes by hydrogen peroxide. Evidence for the participation of hydroxyl radicals formed by an iron-catalyzed Haber-Weiss reaction. Starke, P.E., Farber, J.L. J. Biol. Chem. (1985) [Pubmed]
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  8. Oxidative decarboxylation of 4-methylthio-2-oxobutyrate by branched-chain 2-oxo acid dehydrogenase complex. Jones, S.M., Yeaman, S.J. Biochem. J. (1986) [Pubmed]
  9. Methional derived from 4-methylthio-2-oxobutanoate is a cellular mediator of apoptosis in BAF3 lymphoid cells. Quash, G., Roch, A.M., Chantepie, J., Michal, Y., Fournet, G., Dumontet, C. Biochem. J. (1995) [Pubmed]
  10. Kinetics and effects of trace elements and electron complexes on 2-keto-4-methylthiobutyric acid-dependent biosynthesis of ethylene in soil. Arshad, M., Nazli, Z.H., Khalid, A., Zahir, Z.A. Lett. Appl. Microbiol. (2004) [Pubmed]
  11. Nutritional aspect of methionine isomers studied by pulmonary exhalation of dimethyl sulfide and urinary excretion of alpha-keto-gamma-methiolbutyrate in humans. Kaji, H., Saito, N., Hisamura, M., Murao, M., Ishimoto, M., Kondo, H., Saito, K. Jpn. J. Med. (1983) [Pubmed]
  12. The decarboxylation of alpha-keto-gamma-methiolbutyrate in rat liver mitochondria. Dixon, J.L., Benevenga, N.J. Biochem. Biophys. Res. Commun. (1980) [Pubmed]
  13. Oxidation of methionine and 2-hydroxy 4-methylthiobutanoic acid stereoisomers in chicken tissues. Dupuis, L., Saunderson, C.L., Puigserver, A., Brachet, P. Br. J. Nutr. (1989) [Pubmed]
  14. The generation of hydroxyl and alkoxyl radicals from the interaction of ferrous bipyridyl with peroxides. Winston, G.W., Harvey, W., Berl, L., Cederbaum, A.I. Biochem. J. (1983) [Pubmed]
  15. Lactoferrin-catalysed hydroxyl radical production. Additional requirement for a chelating agent. Winterbourn, C.C. Biochem. J. (1983) [Pubmed]
  16. Effects on plasma amino acid concentrations and hepatic branched-chain alpha-keto acid dehydrogenase activity of feeding rats diets containing 9 or 50% casein. Dixon, J.L., Harper, A.E. J. Nutr. (1984) [Pubmed]
  17. Cysteine conjugate beta-lyase of rat kidney cytosol: characterization, immunocytochemical localization, and correlation with hexachlorobutadiene nephrotoxicity. MacFarlane, M., Foster, J.R., Gibson, G.G., King, L.J., Lock, E.A. Toxicol. Appl. Pharmacol. (1989) [Pubmed]
  18. Glutamine metabolism in isolated perfused rat liver. The transamination pathway. Häussinger, D., Stehle, T., Gerok, W. Biol. Chem. Hoppe-Seyler (1985) [Pubmed]
  19. Identification of 2-keto-4-methylthiobutyrate as an intermediate compound in methionine synthesis from 5'-methylthioadenosine. Backlund, P.S., Chang, C.P., Smith, R.A. J. Biol. Chem. (1982) [Pubmed]
 
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