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Chemical Compound Review

Mepyramine maleate     but-2-enedioic acid; N-[(4...

Synonyms: Antihist, Histatex, Histosol, Minihist, Bimaleate, ...
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Disease relevance of Pyranisamine


High impact information on Pyranisamine


Chemical compound and disease context of Pyranisamine


Biological context of Pyranisamine


Anatomical context of Pyranisamine


Associations of Pyranisamine with other chemical compounds


Gene context of Pyranisamine

  • The encoded protein, denoted mE6(1-120)/mE7(1-60), comprises 120 N-terminus amino acids of E6 and 60 N-terminus amino acids of E7 plus a histine tag, was purified on an affinity column, and subsequently characterized by Western blotting [23].


  1. The processive endocellulase CelF, a major component of the Clostridium cellulolyticum cellulosome: purification and characterization of the recombinant form. Reverbel-Leroy, C., Pages, S., Belaich, A., Belaich, J.P., Tardif, C. J. Bacteriol. (1997) [Pubmed]
  2. Association of fever with late-onset pulmonary hypersensitivity responses in the guinea pig. Thorne, P.S., Karol, M.H. Toxicol. Appl. Pharmacol. (1989) [Pubmed]
  3. Microbial transformation of the antihistamine pyrilamine maleate. Formation of potential mammalian metabolites. Hansen, E.B., Cerniglia, C.E., Korfmacher, W.A., Miller, D.W., Heflich, R.H. Drug Metab. Dispos. (1987) [Pubmed]
  4. Chronic toxicity tests of pyrilamine maleate and methapyrilene hydrochloride in F344 rats. Lijinsky, W. Food Chem. Toxicol. (1984) [Pubmed]
  5. The relation between skin histamine concentration, histamine sensitivity, and the resistance of cattle to the tick, Boophilus microplus. Willadsen, P., Wood, G.M., Riding, G.A. Zeitschrift für Parasitenkunde (Berlin, Germany) (1979) [Pubmed]
  6. Interactions of eosinophil granule proteins with skin: limits of detection, persistence, and vasopermeabilization. Davis, M.D., Plager, D.A., George, T.J., Weiss, E.A., Gleich, G.J., Leiferman, K.M. J. Allergy Clin. Immunol. (2003) [Pubmed]
  7. Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species. Arlt, W., Martens, J.W., Song, M., Wang, J.T., Auchus, R.J., Miller, W.L. Endocrinology (2002) [Pubmed]
  8. Effect of histamine on proliferation of normal human adult lung fibroblasts. Jordana, M., Befus, A.D., Newhouse, M.T., Bienenstock, J., Gauldie, J. Thorax (1988) [Pubmed]
  9. Formation of ovarian follicular cysts and corpora lutea after treatment with antihistamine or indomethacin in prepubertal gilts. Hall, J.A., Meisterling, E.M., Lewis, P.E., Dailey, R.A. Biol. Reprod. (1989) [Pubmed]
  10. Pharmacological studies of sensitized canine pulmonary blood vessels. Kong, S.K., Stephens, N.L. J. Pharmacol. Exp. Ther. (1981) [Pubmed]
  11. Effect of some drugs on the skin response of tick-resistant cattle to an allergenic extract of larval Rhipicephalus appendiculatus. Binta, M.G., Cunningham, M.P., Mushi, E.Z. Vet. Res. Commun. (1984) [Pubmed]
  12. Negligible potency of acetylcholine in increasing vascular permeability. Kawana, S., Katori, M. Archives internationales de pharmacodynamie et de thérapie. (1980) [Pubmed]
  13. Suppression by mepyramine maleate of the increased vascular permeability in passive cutaneous anaphylaxis in the chicken. Pillai, A.G., Awadhiya, R.P., Vegad, J.L. Vet. Res. Commun. (1988) [Pubmed]
  14. Characterization of DNA repair elicited by carcinogens and drugs in the hepatocyte primary culture/DNA repair test. McQueen, C.A., Williams, G.M. Journal of toxicology and environmental health. (1981) [Pubmed]
  15. Histosol: a clearing agent for hard tissue histology and special staining technics. Roy, M., Wishe, H.I., Piliero, S.J. Journal of oral medicine. (1983) [Pubmed]
  16. Metabolism of pyrilamine maleate in Fischer 344 rats, Part I: Activity excretion profiles. Thompson, H.C., Holder, C.L., Siitonen, P.H., Rowland, K.L., Gosnell, A.B., Cmarik, J.L. Journal of analytical toxicology. (1987) [Pubmed]
  17. Studies in experimental eosinophilia. XI. Dependence of eosinophilia, apparently induced by histamine, on acidity. Litt, M. Int. Arch. Allergy Appl. Immunol. (1976) [Pubmed]
  18. Effect of mepyramine on the untoward side-effects of impromidine. Bank, L., Marks, I.N., Lipschitz, E., Bortz, D. S. Afr. Med. J. (1984) [Pubmed]
  19. Fibrin-derived vasoactive peptides release histamine. Eriksson, M., Saldeen, K., Saldeen, T., Strandberg, K., Wallin, R. International journal of microcirculation, clinical and experimental / sponsored by the European Society for Microcirculation. (1983) [Pubmed]
  20. Regulation by prostaglandin E2 and histamine of angiogenesis in inflammatory granulation tissue. Ghosh, A.K. Yakugaku Zasshi (2003) [Pubmed]
  21. Interaction between histamine and adenosine in human cerebromicrovascular endothelial cells: modulation of second messengers. Stanimirovic, D.B., Bertrand, N., Merkel, N., Bembry, J., Spatz, M. Metabolic brain disease. (1994) [Pubmed]
  22. Effect of antioxidants, anti-inflammatory drugs, and histamine antagonists on sparfloxacin-induced phototoxicity in mice. Shimoda, K., Nomura, M., Kato, M. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1996) [Pubmed]
  23. Efficient expression of modified human papillomavirus 16 e6/e7 fusion protein and the antitumor efficacy in a mouse model. Zhou, X., Qian, X., Zhao, Q., Lu, Y., Xiong, M. Biol. Pharm. Bull. (2004) [Pubmed]
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